Local irradiation alone for peripheral stage I lung cancer: Could we omit the elective regional nodal irradiation?

International Journal of Radiation Oncology Biology Physics

Volumn 34, Issue 2, 1996, Pages 297-302

  Krol, Augustinus D G ^a   Aussems, Peter ^a   Noordijk, Evert M ^a   Hermans, Jo ^b   Leer, Jan W H ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURVIVAL; DOSIMETRY; DRUG MEGADOSE; FEMALE; HUMAN; IRRADIATION; LUNG CANCER; LUNG NON SMALL CELL CANCER; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RADIATION DOSE; TREATMENT FAILURE;

EID: 0030042604     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/0360-3016(95)00227-8     Document Type: Article

References (20)

1. Cox, J. D.; Azarnia, N.; Byhardt, R. W.; Shin, K. H.; Emami, B.; Pajak, T. F. A randomized phase I/II trial of hyperfractionated radiation therapy with total doses of 60.0 Gy to 79.2 Gy: Possible survival benefit with ≥ 69.6 Gy in favourable patients with Radiation Therapy Oncology Group Stage III nonsmall cell lung carcinoma: Report of Radiation Therapy Oncology Group 83-11. J. Clin. Oncol. 8:1543-1555; 1990.
2. Coy, P.; Kennelly, G. M. The role of curative radiotherapy in the treatment of lung cancer. Cancer 45:698-702; 1980.
3. Dosoretz, D. E.; Katin, M. J.; Blitzer, P. H. Radiation therapy in the management of medically inoperable carcinoma of the lung: Results and implications for future treatment strategies. Int. J. Radiat. Biol. Phys. 24:3-9; 1992.
4. Dosoretz, D. E.; Galmarini, D.; Rubenstein, J. H.; Karin, M. J.; Blitzer, D. H.; Salenius, S. A.; Dosani, R. A.; Rashid, M.; Mestas, G.; Hannan, S. E.; Chadha, T. T.; Bhat, S. B.; Siegel, A. D.; Chandrahasa, T.; Metke, M. P. Local control in medically inoperable lung cancer: An analysis of its importance in outcome and factors determining the probability of tumor eradication. Int. J. Radiat. Biol. Phys. 27:507-516; 1993.
5. Haffty, B. G. Is radiation therapy a viable alternative to surgery in early stage lung cancer? (Editorial.) Int. J. Radiat. Oncol. Biol. Phys. 19:223-224; 1990.
6. Haffty, B. G.; Goldberg, N. B.; Gerstley, J.; Fischer, D. B.; Peschel, R. E. Results of radical radiation therapy in clinical Stage I, technically operable nonsmall cell lung cancer. Int. J. Radiat. Oncol. Biol. Phys. 15:69-73; 1988.
7. Hilton, G. Present position relating to cancer of the lung; results with radiotherapy alone. Thorax 15:17-18; 1960.
8. Holsti, L. R.; Mattson, K. A randomized study of split course radiotherapy of lung cancer: Long term results. Int. J. Radiat. Biol. Phys. 6:977-981; 1980.
9. Kaskowitz, L.; Graham, M. V.; Emami, B.; Halverson, K. J.; Rush, C. Radiation therapy alone for stage I nonsmall cell lung cancer. Int. J. Radiat. Biol. Phys. 27:517-523; 1993.
10. Lee, R. E.; Carr, D. T.; Childs, D. S. Comparison of split course radiation therapy and continuous radiation therapy for unresectable bronchogenic carcinoma: 5 year results. Am. J. Roentgenol. 126:116-122; 1976.
11. Levitt, S. H.; Bogardus, C. R.; Ladd, G. Split dose intensive radiation therapy in the treatment of advanced lung cancer: A randomized study. Radiology 88:1159-1169; 1967.
12. Noordijk, E. M.; van der Poest, Clement E.; Hermans, J.; Wever, A. M. J.; Leer, J. W. H. Radiotherapy as an alternative to surgery in elderly patients with resectable lung cancer. Radiother. Oncol. 13:83-89; 1988.
13. Perez, C. A.; Stanley, K.; Hanson, W.; Rubin, P.; Kramer, S.; Brady, L. W.; Marks, J. E.; Perez-Tanayo, R.; Brown, G. S.; Concannon, J. P.; Rotman, M. Impact of irradiation technique and tumor extent in tumor control and survival of patients with unresectable noncat cell carcinoma of the lung. Cancer 50:1091-1099; 1982.
14. Perez, C. A.; Pajak, T. F.; Rubin, P.; Simpson, J. R.; Mohiuddin, M.; Brady, L. W.; Perez-Tamayo, R.; Rotman, M. Long-term observations of the patterns of failure in patients with unresectable noncat cell carcinoma of the lung treated with definitive radiotherapy. Report by the Radiation Therapy Oncology Group. Cancer 59:1874-1881; 1987.
15. Sandler, H. M.; Curran, W. J.; Turrisi, A. T. The influence of tumor size and pretreatment staging on outcome following radiation therapy alone for Stage I nonsmall cell lung cancer. Int. J. Radiat. Oncol. Biol. Phys. 19:9-13; 1990.
16. Slotman, B. J.; Njo, K. H.; Karim, A. B. M. Curative radiotherapy for technically operable stage I nonsmall cell lung cancer. Int. J. Radiat. Biol. Phys. 29:33-37; 1994.
17. Smart, J. Can lung cancer be cured by irradiation alone? J. Am. Med. Assoc. 195:1034-1035; 1965.
18. Talton, B. M.; Constable, W. C.; Kersh, C. R. Curative radiotherapy in nonsmall cell carcinoma of the lung. Int. J. Radiat. Oncol. Biol. Phys. 19:15-21; 1990.
19. Würschmidt, F.; Bünemann, H.; Bemann, C.; Beck-Bornholdt, H. P.; Heilmann, H. P. Inoperable nonsmall cell lung cancer: A retrospective analysis of 427 patients treated with high dose radiotherapy. Int. J. Radiat. Biol. Phys. 28:583-588; 1994.
20. Zhang, H. X.; Yin, W. B.; Zhang, L. J.; Yang, Z. Y.; Zhang, X. X.; Wang, M.; Chen, D. F.; Gu, X. Z. Curative radiotherapy of early operable nonsmall cell lung cancer. Radiother. Oncol. 14:89-94; 1989.