Preparation of ion-activated in situ gel systems of scopolamine hydrobromide and evaluation of its antimotion sickness efficacy

Acta Pharmacologica Sinica

Volumn 28, Issue 4, 2007, Pages 584-590

  Cao, Shi Lei ^a   Zhang, Qi Zhi ^a   Jiang, Xin Guo ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Gellan gum; Motion sickness; Nasal ciliotoxicity; Nasal delivery; Residence time; Scopolamine

Indexed keywords

SCOPOLAMINE BROMIDE; TECHNETIUM 99M;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG FORMULATION; GEL; ION TRANSPORT; MALE; MOTION SICKNESS; NONHUMAN; RABBIT; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; VISCOSITY;

ADMINISTRATION, INTRANASAL; ANIMALS; ANTIEMETICS; CHEMISTRY, PHARMACEUTICAL; CILIA; EXCIPIENTS; GELS; MALE; MOTION SICKNESS; NASAL MUCOSA; POLYSACCHARIDES, BACTERIAL; RATS; RATS, WISTAR; SCOPOLAMINE; VISCOSITY;

EID: 33947699809     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2007.00540.x     Document Type: Article

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