Expression of transmembrane protein tyrosine phosphatase gamma (PTPγ) in normal and neoplastic human tissues

Histopathology

Volumn 50, Issue 5, 2007, Pages 615-628

  Vezzalini, M ^a   Mombello, A ^a   Menestrina, F ^a   Mafficini, A ^a   Della Peruta, M ^a   Van Niekerk, C ^b   Barbareschi, M ^c   Scarpa, A ^a   Sorio, C ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c SANTA CHIARA HOSPITAL   (Italy)

Author keywords

Cancer; Endocrine; Immunohistochemistry; Tumour suppressor gene; Tyrosine phosphatase

Indexed keywords

ANTIBODY; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE GAMMA; UNCLASSIFIED DRUG;

ADRENAL MEDULLA; ARTICLE; ASTROCYTOMA; BRAIN NERVE CELL; BRAIN TISSUE; BREAST TUMOR; CELL MEMBRANE; CONTROLLED STUDY; CYTOPLASM; ENDOCRINE CELL; EPITHELIUM CELL; GASTROINTESTINAL TRACT; GLIA CELL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; LUNG TUMOR; LYMPHOMA; OVARY TUMOR; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; THYROID FOLLICLE CELL; TISSUE DISTRIBUTION;

DOWN-REGULATION; ENDOCRINE SYSTEM; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOENZYME TECHNIQUES; IN SITU HYBRIDIZATION; MALE; NEOPLASMS; NERVE TISSUE PROTEINS; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, CELL SURFACE; RNA, MESSENGER; RNA, NEOPLASM; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 33947698314     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/j.1365-2559.2007.02661.x     Document Type: Article

References (19)

1. Barnea G, Silvennoinen O, Shaanan B et al. Identification of a carbonic anhydrase-like domain in the extracellular region of RPTP gamma defines a new subfamily of receptor tyrosine phosphatases. Mol. Cell. Biol. 1993; 13; 1497-1506.
2. Tsukamoto T, Takahashi T, Ueda R, Hibi K, Saito H. Molecular analysis of the protein tyrosine phosphatase gamma gene in human lung cancer cell lines. Cancer Res. 1992; 52; 3506-3509.
3. Shintani T, Maeda N, Noda M. Receptor-like protein tyrosine phosphatase gamma (RPTPgamma), but not PTPzeta/RPTP-beta, inhibits nerve-growth-factor- induced neurite outgrowth in PC12D cells. Dev. Neurosci. 2001; 23; 55-69.
4. Sorio C, Melotti P, D'Arcangelo D et al. Receptor protein tyrosine phosphatase gamma, Ptp gamma, regulates hematopoietic differentiation. Blood 1997; 90; 49-57.
5. LaForgia S, Morse B, Levy J et al. Receptor protein-tyrosine phosphatase gamma is a candidate tumor suppressor gene at human chromosome region 3p21. Proc. Natl Acad. Sci. USA 1991; 88; 5036-5040.
6. van Niekerk CC, Poels LG. Reduced expression of protein tyrosine phosphatase gamma in lung and ovarian tumors. Cancer Lett. 1999; 137; 61-73.
7. Liu S, Sugimoto Y, Sorio C, Tecchio C, Lin YC. Function analysis of estrogenically regulated protein tyrosine phosphatase gamma (PTPgamma) in human breast cancer cell line MCF-7. Oncogen 2004; 23; 1256-1262.
8. Wang Z, Shen D, Parsons DW et al. Mutational analysis of the tyrosine phosphatome in colorectal cancers. Science 2004; 304; 1164-1166.
9. van Doorn R, Zoutman WH, Dijkman R et al. Epigenetic profiling of cutaneous T-cell lymphoma: promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73. J. Clin. Oncol. 2005; 23; 3886-3896.
10. Zheng J, Kulp SK, Zhang Y et al. 17 beta-estradiol-regulated expression of protein tyrosine phosphatase gamma gene in cultured human normal breast and breast cancer cells. Anticancer Res. 2000; 20 (1A); 11-19.
11. Sorio C, Mendrola J, Lou Z, LaForgia S, Croce CM, Huebner K. Characterization of the receptor protein tyrosine phosphatase gene product PTP gamma: binding and activation by triphosphorylated nucleosides. Cancer Res. 1995; 55; 4855-4864.
12. Young ID, Ailles L, Deugau K, Kisilevsky R. Transcription of cRNA for in situ hybridization from polymerase chain reaction-amplified DNA. Lab. Invest. 1991; 64; 709-712.
13. Lissandrini D, Vermi W, Vezzalini M et al. Receptor-type protein tyrosine phophastase gamma (PTPgamma), a new identifier for myeloid dendritic cells and specialized macrophages. Blood 2006; 108; 4223-4231.
14. Kappert K, Peters KG, Bohmer FD, Ostman A. Tyrosine phosphatases in vessel wall signaling. Cardiovasc. Res. 2005; 65; 587-598.
15. Freiss G, Vignon F. Protein tyrosine phosphatases and breast cancer. Crit. Rev. Oncol. Hematol. 2004; 52; 9-17.
16. Pitterle DM, Jolicoeur EM, Bepler G. Hot spots for molecular genetic alterations in lung cancer. In Vivo 1998; 12; 643-658.
17. Liu S, Sugimoto Y, Kulp SK et al. Estrogenic down-regulation of protein tyrosine phosphatase gamma (PTP gamma) in human breast is associated with estrogen receptor alpha. Anticancer Res. 2002; 22; 3917-3923.
18. Molina R, Barak V, van Dalen A et al. Tumor markers in breast cancer - European Group on Tumor Markers recommendations. Tumour Biol. 2005; 26; 281-293.
19. Gee JM, Robertson JF, Gutteridge E et al. Epidermal growth factor receptor/HER2/insulin-like growth factor receptor signalling and oestrogen receptor activity in clinical breast cancer. Endocr. Relat. Cancer 2005; 12 (Suppl. 1); S99-S111.