The effect of the postnatal environment on altered fetal programming of adult vascular function in mice that lack endothelial nitric oxide synthase

American Journal of Obstetrics and Gynecology

Volumn 196, Issue 4, 2007, Pages 354.e1-354.e7

  Clark, Shannon M ^a   Makhlouf, Michel ^a   Hankins, Gary D V ^a   Anderson, Garland D ^a   Saade, George R ^a   Longo, Monica ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

cross fostering; fetal programming; hypertension; vascular reactivity

Indexed keywords

ACETYLCHOLINE; CALCIUM; ISOPRENALINE; N(G) NITROARGININE METHYL ESTER; PHENYLEPHRINE;

ALLELE; ANALYSIS OF VARIANCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL FUNCTION; BLOOD VESSEL REACTIVITY; CAROTID ARTERY; CHEMOSENSITIVITY; CONTROLLED STUDY; CROSS FOSTERING; ENZYME DEFICIENCY; FEMALE; FETUS; FETUS DISEASE; GENETIC PREDISPOSITION; HETEROZYGOSITY; HOMOZYGOSITY; HYPERTENSION; KNOCKOUT GENE; MALE; MOUSE; MUSCLE ISOMETRIC CONTRACTION; NEWBORN; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; VASODILATATION;

EID: 33947686617     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2007.01.031     Document Type: Article

References (17)

1. Barker D.J.P., and Osmond C. Infant mortality, childhood nutrition and ischaemic heart disease in England and Wales. Lancet 1 (1986) 1077-1081
2. Barker D.J.P. In utero programming of cardiovascular disease. Theriogenology 53 (2000) 555-574
3. Moore T. Genetic conflict, genomic imprinting and establishment of the epigenotype in relation to growth. Reproduction 122 (2001) 185-193
4. Wu K.K. Inducible cyclooxygenase and nitric oxide synthase. Adv Pharmacol 33 (1995) 179-207
5. Forstermann U., and Kleinert H. Nitric oxide synthase: expression and expressional control of the three isoforms. Naunyn Schmiedebergs Arch Pharmacol 352 (1995) 351-364
6. Maul H., Longo M., Saade G.R., and Garfield R.E. Nitric oxide and its role during pregnancy: from ovulation to delivery. Curr Pharmacol Des 9 (2003) 359-380
7. Longo M., Jain V., Anderson G., Vedernikov Y., Garfield R.E., and Saade G.R. Effect of in-utero environment and genetic imprinting on future vascular reactivity in transgenic mice lacking a functional endothelial nitric oxide synthase. Am J Obstet Gynecol 186 suppl (2002) S19
8. Longo M., Jain V., Langenveld J., et al. Embryo transfer prevents development of abnormal vascular function in offspring of endothelial nitric oxide synthase knockout mice. [abstract]. J Soc Gynecol Investig 11 suppl (2004) 294A
9. Hurst L.D. Is multiple paternity necessary for the evolution of genomic imprinting?. Genetics 153 (1999) 112-124
10. Tycko B., and Morrison I.M. Physiological functions of imprinted genes. J Cell Physiol 192 (2002) 245-258
11. Rotmensch S., Liberati M., Luo J.S., et al. Color Doppler flow patterns and velocity waveforms of the intraplacental fetal circulation in growth-retarded fetuses. Am J Obstet Gynecol 171 (1994) 1257-1264
12. Henrikson T., and Clausen T. The fetal origins hypothesis: placental insufficiency and inheritance versus maternal malnutrition in well-nourished populations. Acta Obstet Gynecol Scand 81 (2002) 112-124
13. McCarty R., and Lee J.H. Maternal influences on adult blood pressure of SHRs: a single pup cross-fostering study. Physiol Behav 59 (1996) 71-76
14. Winslow J.T., Hearn E.F., Ferguson J., Young L.J., Matzuk M.M., and Insel T. Infant vocalization, adult aggression and fear behavior of an oxytocin null mutant mice. Horm Behav 37 (2000) 145-155
15. Longo M., Jain V., Vedernikov Y., et al. Fetal origins of adult vascular dysfunction in mice lacking endothelial nitric oxide synthase. Am J Physiol Regul Integr Comp Physiol 288 (2004) R1114-R1121
16. Kodja G., Laursen J., Ramasamy S., et al. Protein expression, vascular reactivity and soluble guanylate cyclase activity in mice lacking the endothelial cell nitric oxide synthase: contributions of NOS isoforms to blood pressure and heart rate control. Cardiovasc Res 42 (1999) 206-213
17. Cook S., Hugli O., Egli M., et al. Partial gene deletion of endothelial nitric oxide synthase predisposes to exaggerated high-fat diet-induced insulin resistance and arterial hypertension. Diabetes 53 (2004) 2067-2072