Association study between the dopamine receptor D4 gene and obsessive-compulsive disorder

European Neuropsychopharmacology

Volumn 17, Issue 6-7, 2007, Pages 406-409

  Camarena, Beatriz ^a   Loyzaga, Cristina ^a   Aguilar, Alejandro ^a   Weissbecker, Karen ^b   Nicolini, Humberto ^c,d  

^a INSTITUTO NACIONAL DE PSIQUIATRÍA RAMÓN DE LA FUENTE MUÑIZ   (Mexico)

^b TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^c Grupo Medico Carracci   (Mexico)

^d UNIVERSIDAD AUTÓNOMA DE LA CIUDAD DE MÉXICO   (Mexico)

Author keywords

Dopamine D4 receptor gene; ; Gender; ; OCD; ; Tics

Indexed keywords

DOPAMINE 4 RECEPTOR;

ADULT; ARTICLE; CONTROLLED STUDY; DRD4 GENE; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROANATOMY; OBSESSIVE COMPULSIVE DISORDER; PATHOGENESIS; PRIORITY JOURNAL; RECEPTOR GENE;

FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; MALE; MEXICO; OBSESSIVE-COMPULSIVE DISORDER; POLYMORPHISM, GENETIC; RECEPTORS, DOPAMINE D4; REFERENCE VALUES;

EID: 33947666627     PISSN: 0924977X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2006.08.001     Document Type: Article

References (28)

1. Ardlie K.G., Lunetta K.L., and Seielstad M. Testing for population subdivision and association in four case-control studies. Am. J. Hum. Genet. 71 (2002) 304-311
2. Baker R.W., Chengappa K.N., Baird J.W., Steingard S., Christ M.A., and Schooler N.R. Emergence of obsessive compulsive symptoms during treatment with clozapine. J. Clin. Psychiatry 53 (1992) 439-442
3. Ben-Pazi A., Szechtman H., and Eilam D. The morphogenesis of motor rituals in rats treated chronically with the dopamine agonist quinpirole. Behav. Neurosci. 115 (2001) 1301-1317
4. Billett E.A., Richter M.A., Sam F., Swinson R.P., Dai X.Y., King N., Badri F., Sasaki T., Buchanan J.A., and Kennedy J.L. Investigation of dopamine system genes in obsessive-compulsive disorder. Psychiatr. Genet. 8 (1998) 163-169
5. Camarena B., Rinetti G., Cruz C., Gomez A., de La Fuente J.R., and Nicolini H. Additional evidence that genetic variation of MAO-A gene supports a gender subtype in obsessive-compulsive disorder. Am. J. Med. Genet. 105 (2001) 279-282
6. Caraveo J., González C., and Ramos L. Concurrent validity of the DIS experience with psychiatric patient in Mexico City. Hispanic J. Behav. Sci. 13 (1991) 63-67
7. 4 receptor gene in patients with obsessive-compulsive disorder with tics. Neurosci. Lett. 231 (1997) 1-4
8. Derogatis L.R., Lipman R.S., and Covi L. SCL-90: an outpatient psychiatric rating scale - preliminary report. Psychopharmacol. Bull. 9 (1973) 13-28
9. 2 receptor binding in obsessive-compulsive disorder. Biol. Psychiatry 55 (2004) 1041-1045
10. Denys D., Zohar J., and Wastenberg H.G.M. The role of dopamine in obsessive-compulsive disorder: preclinical and clinical evidence. J. Clin. Psychiatry 65 suppl 14 (2004) 11-17
11. Di Giovanni G., Di Matteo V., Di Mascio M., and Esposito E. Preferential modulation of mesolimbic vs nigrostriatal dopaminergic function by serotonin (2C/2B) receptor agonists: a combined in vivo electrophysiological and microdialysis study. Synapse 35 (2000) 53-61
12. 2A promoter polymorphism with obsessive-compulsive disorder. Biol. Psychiatry 49 (2001) 385-388
13. Ghaemi S.N., Zarate Jr. C.A., Popli A.P., Pillay S.S., and Cole J.O. Is there a relationship between clozapine and obsessive-compulsive disorder? A retrospective chart review. Comp. Psychiatry 36 (1995) 267-270
14. Hemmings S.M., Kinnear C.J., Lochner C., Niehaus D.J., Knowles J.A., Moolman-Smook J.C., Corfield V.A., and Stein D.J. Early- versus late-onset obssesive-compulsive disorder: investigating genetic and clinical correlates. Psychiatry Res. 128 (2004) 175-182
15. Karayiorgou M., Sobin C., Blundell M.L., Galke B.L., Malinova L., Goldberg P., Ott J., and Gogos J.A. Family-based association studies support a sexually dimorphic effect of COMT and MAOA on genetic susceptibility to obsessive-compulsive disorder. Biol. Psychiatry 45 (1999) 1178-1189
16. Lazzeroni L., and Lange K. A conditional inference framework for extending the transmission/disequilibrium test. Hum. Hered. 48 (1998) 67-81
17. Lechman J.F., Riddle M.A., Hardin M.T., Ort S.I., Swartz K.L., Stevenson J., and Cohen D.J. The Yale Global Tic Severity Scale: initial testing of a clinician-rated scale of tic severity. J. Am. Acad. Child Adolesc. Psych. 28 (1989) 566-573
18. 4) gene. Hum. Mol. Genet. 2 (1993) 767-773
19. Lochner C., Hemmings S.M., Kinnear C.J., Moolman-Smook J.C., Corfield V.A., Knowles J.A., Niehaus D.J., and Stein D.J. Gender in obsessive-compulsive disorder: clinical and genetic findings. Eur. Neuropsychopharmacol. 14 (2004) 105-113
20. 4) gene and obsessive-compulsive disorder. Am. J. Med. Genet. 116B (2003) 55-59
21. Nestadt G., Lan T., Samuels J., Riddle M., Bienvenu III O.J., Liang K.Y., Hoehn-Saric R., Cullen B., Grados M., Beaty T.H., and Shugart Y.Y. Complex segregation analysis provides compelling evidence for a major gene underlying obsessive-compulsive disorder and for heterogeneity by sex. Am. J. Hum. Genet. 67 (2000) 1611-1616
22. Nicolini H., Orozco B., Sánchez de Carmona M., Páez F., Loreido G., and de la Fuente J.R. Estudio de traducción y confiabilidad de la escala Yale-Brown en español para el trastorno obsesivo-compulsivo. Salud Ment. 19 Suppl. 3 (1996) 13-16
23. Risch N., and Teng J. The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases: I. DNA pooling. Genome Res. 8 (1998) 1273-1288
24. Sham P.C., and Curtis D. An extended transmission/disequilibrium test (TDT) for multi-allelle marker loci. Ann. Hum. Genet. 59 (1995) 323-336
25. 11C]raclopride and PET in normal human subjects. Am. J. Psychiatry 154 (1997) 490-496
26. Stahl S.M. Basal ganglia neuropharmacology and obsessive-compulsive disorder: the obsessive-compulsive disorder hypothesis of basal ganglia dysfunction. Psychopharmacol. Bull. 24 (1988) 370-374
27. Sullivan R.M., Talangbayan H., Einat H., and Szechtman H. Effects of quinpirole on central dopamine systems in sensitized and non-sensitized rats. Neuroscience 83 (1998) 781-789
28. Szechtman H., Sulis W., and Eilam D. Quinpirole induces compulsive checking behavior in rats: a potential animal model of obsessive-compulsive disorder (OCD). Behav. Neurosci. 112 (1998) 1475-1485