Evaluation of the efficacy of whey protein to ameliorate the toxic effects of aflatoxins in rats

International Dairy Journal

Volumn 17, Issue 7, 2007, Pages 854-859

  Saleh, Zeinab A ^a   El Garawany, Gamaal A ^a   Assem, Fayza ^a   El Shibiny, Safinaz ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Aflatoxins; Malondialdehyde glutathione; Whey protein

Indexed keywords

AFLATOXINS; CONTAMINATION; DAIRY PRODUCTS; PARAMETER ESTIMATION; RATS; TOXICITY;

AFLATOXICOSIS; CASEIN DIET; MALONDIALDEHYDE GLUTATHIONE; WHEY PROTEINS;

PROTEINS;

RATTUS;

EID: 33947648501     PISSN: 09586946     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.idairyj.2006.09.014     Document Type: Article

References (52)

1. Alias C., and Jolles P. Etude comparee des caseinoglycopeptides formes par action de la presure sur les caseines de vache, de brebis et de chevre. II. Etude de la partie non-peptidique. (Studies comparing caseinoglycopeptides formed from cow, sheep, and goat milk casein. II. Studies on the non-peptide fractions). Biochimica et Biophysica Acta 51 (1961) 315-322
2. Ammerman C.B., Chapman M.L., Bouwman G.W., Pontenol J.P., Blagley C.P., and Moxan A.L. Effect of supplemental selenium for beef cows on the performance and tissue selenium concentrations of caws and suckling calves. Journal of Animal Science 51 (1980) 1381-1386
3. Anderson P.H., Berret S., and Patterson D.S.P. Glutathione peroxidase activity in erythrocytes and muscle in cattle and sheep and its relationship to selenium. Journal of Comparative Pathology 88 (1978) 181-189
4. Belfield A., and Goldberg D.M. Revised assay for serum phenyl phosphatase activity using 4-amino-antipyrine. Enzyme 12 (1971) 561-573
5. Bounous G. Whey protein concentrate (WPC) and glutathione modulation in cancer treatment. Anticancer Research 20 6C (2000) 4785-4792
6. Bounous G., Gervais F., Amer V., Batist G., and Gold P. The influence of dietary whey protein on tissue glutathione and disease of aging. Clinical and Investigative Medicine 12 (1989) 343-349
7. Bounous G., Batist G., and Gold P. Whey proteins in cancer prevention. Cancer Letters 5 (1991) 91-94
8. Brunner J.R. Milk protein. In: Whitaker J.R., and Tannenbaum S.R. (Eds). Food protein (1977), AVI, Co, Westport, CT, USA 175-204
9. Buetler E., Duron O., and Kelly B.M. Improved method for the determination of blood glutathione. Journal of Laboratory and Clinical Medicine 61 (1963) 882-890
10. Caffin J.P., Poutrel B., and Rainard P. Physiological and pathological functions influencing bovine alpha-lactalbumin and beta-lactoglobulin concentrations in milk. Journal of Dairy Science 68 (1985) 1087-1094
11. CAST. Mycotoxins: Economic and health risks (1989), Council for Agricultural Science and Technology, Ames, IA, USA
12. Cook W.O., Van Alstine W.G., and Osweiler G.D. Aflatoxicosis in Iowa swine: Eight cases (1983-1985). Journal of the American Veterinary Medical Association 194 (1989) 554-558
13. Czuczejko J., Zachara B.A., Staubach-Topczewska E., Halota W., and Kedziora J. Selenium, glutathione and glutathione peroxidase in blood of patients with liver diseases. Acta Biochimica Polonica 50 (2003) 1147-1154
14. 1 by Aspergillus flavus in a semisynthetic medium. Applied Microbiology 14 (1966) 378-380
15. Duncan D.B. Multiple range and multiple F-tests. Biometrics 11 (1955) 1-12
16. Eaton D.L., and Gallagher E.P. Mechanisms of aflatoxin carcinogensis. Annual Review of Pharmacology and Toxicology 34 (1994) 135-172
17. Fernandez A., Hernandez M., Verde M.T., and Sanz M. Effect of aflatoxin on performance, hematology, and clinical immunology in lambs. Canadian Journal of Veterinary Research 64 (2000) 53-58
18. Glahn R.P., Van Campen D., and Dousa T.P. Aflatoxin B1 reduces Na(+)-P(i) co-transport in proximal renal epithelium: Studies in opossum kidney (OK) cells. Toxicology 92 (1994) 91-100
19. Gindler E.M., and Heath D.A. Colorimetric determination with bound calmagite of magnesium in human blood serum. Clinical Chemistry 17 (1971) 662
20. Gindler E.M., and King J.D. Rapid colorimetric determination of calcium in biologic fluids with methylthymol blue. American Journal of Clinical Pathology 58 (1972) 376-382
21. Gradelet S., Astorg P., LeBon A.M., Berges R., and Suschetet M. Modulation of Aflatoxin B1 carcinogenicity, genotoxicity and metabolism in rat liver by dietary carotinoids: Evidence for a protective effect of CYP!A inducers. Cancer Letters 114 (1997) 221-223
22. Groopman J.D., Cain L.G., and Kensler T.W. Aflatoxin exposure in human population: Measurements in relation to cancer. CRC Critical Review in Toxicology 19 (1988) 113-145
23. Harvey R.B., Kubena L.F., Huff W.E., Corrier D.E., and Phillips T.D. Progression of aflatoxicosis in growing barrows. American Journal of Veterinary Research 49 (1988) 482-487
24. Hayes J.D., Judah D.J., and Neal G.E. Resistance to aflatoxin B1 is associated with the expression of a novel aldo-keto reductase which has catalytic activity towards a cytotoxic aldehyde-containing metabolite of the toxin. Cancer Research 53 (1993) 3887-3894
25. Horton, B. (1997). The whey processing industry. Into the 21st Century. In: Proceedings of the Second International whey conference, Chicago, USA, 27-29 October. International Dairy Federation. pp. 12-25.
26. 1. Journal of Applied Toxicology 4 (1984) 241-245
27. Kelleher S.L., Chatterton D., Nielsen K., and Lnnerdal B. Glycomacropeptide and α-lactalbumin supplementation of infant formula affects growth and nutritional status in infant rhesus monkeys. American Journal of Clinical Nutrition 77 (2003) 1261-1268
28. Kent K.D., Harper W.J., and Bomser J.A. Effect of whey protein isolate on intracellular glutathione and oxidant-induced cell death in human prostate epiothelial cells. Toxicology In Vitro 17 (2003) 27-33
29. 1. Free Radical Research Communication 10 (1990) 137-142
30. Lynch G.P., Shalkop W.T., Jacoby N.M., Smith D.F., and Miller R.W. Responses of dairy calves to oral doses of aflatoxin. Journal of Dairy Science 54 (1971) 1688-1698
31. Marshall K. Therapeutic applications of whey protein. Alternative Medicine Review 9 (2004) 136-156
32. McIntosh G.H., Regester G.O., LeLeu R.K., Royle P.J., and Smithers G.W. Dietary proteins protect against dimethylhydrazine-induced intestinal cancer in rats. Journal of Nutrition 125 (1995) 809-816
33. Mclntosh G.H., Royle P.J., LeLeu R.K., Regester G.O., Johnson M.A., Grinsted R.L., et al. Whey proteins as functional food ingredients. International Dairy Journal 8 (1998) 425-434
34. Monroe D.H., and Eaton D.L. Comparative effects of butylated hydroxyanisole on hepatic in vivo DNA binding and in vitro biotransformation of aflatoxin B1 in the rat and mouse. Toxicology and Applied Pharmacology 90 (1987) 401-409
35. Monroe D.H., and Eaton D.L. Effect of modulation of hepatic glutatione on biotransformation and covalent binding of AFB1 to DNA in the mouse. Toxicology and Applied Pharmacology 94 (1988) 118-127
36. Moron M.S., Depierre J.W., and Mannervik B. Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver. Biochimica et Biophysica Acta 582 (1979) 67-78
37. Morr C.V., and Ha E.Y.W. Whey protein concentrates and isolate processing and functional properties. Critical Reviews in Food Science and Nutrition 33 (1993) 431-476
38. Reeves P.G., Nielson F.H., and Fahey Jr. G.C. AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition Ad Hoc writing committee on the reformulation of the AIN-76A rodent diet. Journal of Nutrition 123 (1993) 1939-1951
39. Reitman S., and Frankel S. Colorimetric method for aspartate and alanine amino transferases. American Journal of Clinical Pathology 28 (1957) 56-63
40. Ren J. Alpha-lactalbumin possesses a distinct zinc binding site. Journal of Biological Chemistry 268 (1993) 19292-19298
41. Saleh Z.A., Abdel-kader M.M., El-Shobaki F.A., and El-Hawary Z.M. The Influence of vitamins with reducing characters on toxicity of aflatoxin contaminated diet. The Medical Journal of Cairo University 68 Suppl. (2000) 187-196
42. Satoh K. Serum lipid peroxide in cerbrovascular disorders determinated by a new colorimetric method. Clinica Chimica Acta 20 (1978) 37-43
43. 1 in mixed feeds. Journal Association of Analytical Chemistry 66 (1983) 582-586
44. 1-induced lipid peroxidation in rat liver. Toxicology and Applied Pharmacology 127 (1994) 145-150
45. 1. Free Radical Biology and Medicine 21 (1996) 139-146
46. Smith A.K., and Circle S.J. Soybeans: Chemistry and technology, Vol. I, proteins (pp. 213-216) (1971), AVI Publishing Company, Inc., Wesport, CT, USA
47. Snedecor G.W., and Cochran W.G. Statistical methods, Vol. IA. seventh ed. (1980), Iowa State University Press, Ames, IA, USA
48. Sunderman Jr. F.W., and Sunderman F.W. Studies in serum electrolytes. XXII. A rapid, reliable method for serum potassium using tetraphenylboron. American Journal of Clinical Pathology 29 (1958) 95-103
49. Vanderheeren G., Hanssens I., Noyelle K., Dael H.V., and Joniau M. The perturbations of the native state of goat alpha-lactalbumin induced by 1,1_bis(4-anilino-5-naphthalenesulfonate) are Ca+2-dependent. Biophysical Journal 75 (1998) 2195-2204
50. Walzem R.L., Dillard C.J., and German J.B. Whey components: Millennia of evolution create functionalities for mammalian nutrition: What we know and what we may be overlooking. Critical Reviews in Food Science and Nutrition 42 (2002) 353-375
51. Watanabe A., Okada K., Shimizu Y., Wakabayashi H., Higuchi K., Niiya K., et al. Nutritional therapy of chronic hepatitis by whey protein (non-heated). Journal of Medicine 31 (2000) 283-302
52. Wogan G.N. Mycotoxins. Annual Review of Pharmacology 15 (1975) 437-451