Glycomacropeptide and α-lactalbumin supplementation of infant formula affects growth and nutritional status in infant rhesus monkeys

American Journal of Clinical Nutrition

Volumn 77, Issue 5, 2003, Pages 1261-1268

  Kelleher, Shannon L ^a   Chatterton, Dereck ^b   Nielsen, Karin ^b   Lönnerdal, Bo ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Arla Foods   (Denmark)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Amino acids; Formula; Glycomacropeptide; Infants; Monkeys; Trace minerals; lactalbumin

Indexed keywords

ALPHA LACTALBUMIN; AMINO ACID; CALCIUM; GLYCOPROTEIN; INSULIN; IRON; TRACE ELEMENT; UREA; ZINC; CASEIN; GLYCOPEPTIDE; LACTALBUMIN;

AMINO ACID BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; BREAST FEEDING; CALCIUM ABSORPTION; CALCIUM BLOOD LEVEL; CONTROLLED STUDY; DIET SUPPLEMENTATION; FOOD INTAKE; GROWTH CURVE; HEMATOCRIT; INSULIN BLOOD LEVEL; IRON BLOOD LEVEL; NONHUMAN; NUTRITIONAL STATUS; RHESUS MONKEY; UREA BLOOD LEVEL; ZINC BLOOD LEVEL; ANIMAL; ANIMAL MODEL; BABY FOOD; BLOOD; BREAST MILK; CHEMISTRY; CHILD DEVELOPMENT; DRUG EFFECT; GROWTH, DEVELOPMENT AND AGING; HUMAN; INFANT; INFANT NUTRITION; INTESTINE ABSORPTION; MACACA; METABOLISM; MILK; NEWBORN; UREA NITROGEN BLOOD LEVEL;

BOS TAURUS; MACACA MULATTA;

AMINO ACIDS; ANIMALS; BLOOD UREA NITROGEN; CALCIUM; CASEINS; CHILD DEVELOPMENT; DIETARY SUPPLEMENTS; GLYCOPEPTIDES; HUMANS; INFANT; INFANT FOOD; INFANT NUTRITION PHYSIOLOGY; INFANT, NEWBORN; INTESTINAL ABSORPTION; IRON; LACTALBUMIN; MACACA MULATTA; MILK; MILK, HUMAN; MODELS, ANIMAL; NUTRITIONAL STATUS; TRACE ELEMENTS; ZINC;

EID: 0038474028     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/77.5.1261     Document Type: Article

References (28)

1. Picciano MF. Human milk: nutritional aspects of a dynamic food. Biol Neonate 1998;74:84-93.
2. Knudsen E, Sandström B, Anderson O. Zinc and manganese bioavailability from human milk and infant formula used for very low birthweight infants evaluated in a rat pup model. Biol Trace Elem Res 1995;49:53-65.
3. Jochum F, Fuchs A, Cser A, Menzel H, Lombeck I. Trace mineral status of full term infants fed human milk, milk-based formula or partially hydrolyzed whey protein formula. Analyst 1995;120:905-9.
4. Goldman AS. The immune system of human milk: antimicrobial, antiinflammatory and immunomodulating properties. Pediatr Infect Dis J 1993;12:664-672.
5. Alais C, Jolles P. Etude comparee des caseinoglycopeptides formes par action de la presure sur les caseines de vache, de brebis et de chevre. II. Etude de la partie non-peptidique. (Studies comparing caseinoglycopeptides formed from cow, sheep, and goat milk casein. II. Studies on the non-peptide fraction.) Biochim Biophys Acta 1961;51:315-22 (in French).
6. Caffin JP, Poutrel B, Rainard P. Physiological and pathological functions influencing bovine alpha-lactalbumin and beta-lactoglobulin concentrations in milk. J Dairy Sci 1985;68:1087-94.
7. Ren J. Alpha-lactalbumin possesses a distinct zinc binding site. J Biol Chem 1993;268:19292-8.
8. +2-dependent. Biophys J 1998;75:2195-204.
9. Darling PB, Dunn M, Sarwar G, Brookes S, Ball RO, Pencharz PB. Threonine kinetics in preterm infants fed their mother's milk or formula with various ratios of whey to casein. Am J Clin Nutr 1999;69:105-14.
10. Karlsland Äkeson PM, Axelsson IEM, Räihä NCR. Protein and amino acid metabolism in three- to twelve-month-old infants fed human milk or formulas with varying protein concentrations. J Pediatr Gastroenterol Nutr 1998;26:297-304.
11. Heine W, Radke M, Wutzke KD, Peters E, Kundt G. Alpha-lactalbumin- enriched low-protein infant formulas: a comparison to breast milk feeding. Acta Paediatr 1996;85:1024-8.
12. Chatterton DE, Henrik HH. A process for preparing a kappa-caseino glycomacropeptide or a derivative thereof. Viby, Denmark: MD Foods AMBA, 1999.
13. Holt C, McPhail D, Nevison I, et al. Apparent chemical composition of nine commercial or semi-commercial whey protein concentrates, isolates and fractions. Int J Food Sci 1999;34:543-56.
14. Picone TA, Benson JD, Moro G, et al. Growth, serum biochemistries, and amino acids of term infants fed formulas with amino acid and protein concentrations similar to human milk. J Pediatr Gastroenterol Nutr 1989;351-60.
15. Lönnerdal B, Keen CL, Glazier CE, Anderson J. A longitudinal study of rhesus monkey (Macaca mulatta) milk composition: trace elements, minerals, protein, carbohydrate and fat. Pediatr Res 1984;18:911-4.
16. Clegg MS, Keen CL, Lönnerdal B, Hurley LS. Influence of ashing techniques on the concentration of trace elements in animal tissues. 1. Wet ashing. Biol Trace Elem Res 1981;3:107-15.
17. Moore D, Spackman E, Stein R. The use of ion exchange chromatography in amino acid analysis. Anal Chem 1958;30:1185-8.
18. Greger JL, Mulvaney J. Absorption and tissue distribution of zinc, iron and copper by rats fed diets containing lactalbumin, soy and supplemental sulfur-containing amino acids. J Nutr 1985;115:200-10.
19. Wellinghausen N, Rink L. The significance of zinc for leukocyte biology. J Leukoc Biol 1998;64:571-7.
20. Piela Z, Szuber M, Mach B, Janniger CK. Zinc deficiency in exclusively breast fed infants. Cutis 1998;31:197-200.
21. Stevens J, Lubitz L. Symptomatic zinc deficiency in breast fed term and premature infants. J Paediatr Child Health 1998;34:97-100.
22. Krebs N, Reidinger CJ, Miller LV, Hambige KM. Zinc homeostasis in breast fed infants. Pediatr Res 1996;39:661-5.
23. Boehm G, Cervantes H, Georgi G, et al. Effect of increasing dietary threonine intakes on amino acid metabolism of the central nervous system and peripheral tissues in growing rats. Pediatr Res 1998;44:900-6.
24. Lönnerdal B, Hernell O. Effects of feeding ultra-high-temperature (UHT)-treated infant formula with different protein concentrations or powdered formula, as compared with breast feeding, on plasma amino acids, hematology, and trace element status. Am J Clin Nutr 1998;68:350-6.
25. Heinig MJ, Nommsen LA, Peerson JM, Lönnerdal B, Dewey KG. Intake and growth of breast fed and formula-fed infants in relation to the timing of the introduction of complementary foods: the DARLING study. Davis Area Research on Lactation, Infant Nutrition and Growth. Acta Paediatr 1993;82:999-1006.
26. Heinig MJ, Nommsen LA, Peerson JM, Lönnerdal B, Dewey KG. Energy and protein intakes of breast fed and formula-fed infants during the first year of life and their association with growth velocity: the DARLING study. Am J Clin Nutr 1993;58:152-61.
27. Dewey KG, Heinig MJ, Nommsen LA, Peerson JM, Lönnerdal B. breast fed infants are leaner than formula-fed infants at 1 y of age: the DARLING study. Am J Clin Nutr 1993;57:140-5.
28. Dewey KG. Growth characteristics of breast fed compared to formula-fed infants. Biol Neonate 1998;74:94-105.