Simulation of cholinesterase status at different scenarios of nerve agent exposure

Toxicology

Volumn 233, Issue 1-3 SPEC. ISS., 2007, Pages 155-165

  Worek, Franz ^a   Eyer, Peter ^b   Szinicz, Ladislaus ^a   Thiermann, Horst ^a  

^a BUNDESWEHR INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Acetylcholinesterase; Carbamates; Human; Model; Organophosphates; Oximes

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; ANTIDOTE; ATROPINE; CARBAMIC ACID DERIVATIVE; CHOLINESTERASE; CHOLINESTERASE REACTIVATOR; METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; MUSCARINIC RECEPTOR BLOCKING AGENT; NERVE GAS; NEUROTOXIN; OBIDOXIME; ORGANOPHOSPHATE; OXIME DERIVATIVE; PRALIDOXIME; PYRIDOSTIGMINE; SARIN; SOMAN; TABUN;

ARTICLE; CHEMICAL WARFARE; COMPUTER MODEL; DRUG ACTIVITY; DRUG EFFICACY; DRUG RESEARCH; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; ENZYME REACTIVATION; ERYTHROCYTE; HOMICIDE; HUMAN; MEDICAL ETHICS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; SIMULATION; SPECIES DIFFERENCE; TERRORISM; TOXICOKINETICS;

ANIMALS; CHEMICAL WARFARE AGENTS; CHOLINESTERASE REACTIVATORS; CHOLINESTERASES; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MODELS, BIOLOGICAL; NEUROTOXICITY SYNDROMES; ORGANOTHIOPHOSPHORUS COMPOUNDS; OXIMES; PREMEDICATION; TIME FACTORS;

ANIMALIA;

EID: 33947627229     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2006.07.002     Document Type: Article

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