Visible light affects mitochondrial function and induces neuronal death in retinal cell cultures

Vision Research

Volumn 47, Issue 9, 2007, Pages 1191-1201

  Lascaratos, Gerassimos ^a   Ji, Dan ^a   Wood, John P M ^a   Osborne, Neville N ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Apoptosis; Glaucoma; Mitochondria; Retinal neurons; Visible light

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 4 AMINOBUTYRIC ACID; BENZENE DERIVATIVE; CASPASE 3; REACTIVE OXYGEN METABOLITE; TROLOX C;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; AUTORADIOGRAPHY; CELL COUNT; CELL CULTURE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENERGY; IMMUNOREACTIVITY; LABELING INDEX; LIGHT; LIGHT DARK CYCLE; LIGHT EXPOSURE; LIVER; MITOCHONDRION; NERVE CELL NECROSIS; NERVE FIBER; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; RETINA; SERUM; STAINING;

ANIMALS; APOPTOSIS; CASPASE 3; CELL SURVIVAL; CELLS, CULTURED; DNA DAMAGE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GAMMA-AMINOBUTYRIC ACID; GLAUCOMA; IN SITU NICK-END LABELING; MITOCHONDRIA, LIVER; RADIATION DOSAGE; RADIATION INJURIES; RATS; REACTIVE OXYGEN SPECIES; RETINAL GANGLION CELLS;

EID: 33947603822     PISSN: 00426989     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.visres.2006.12.014     Document Type: Article

References (61)

1. Abu-Amero K.K., Morales J., and Bosley T.M. Mitochondrial abnormalities in patients with primary open-angle glaucoma. Investigative Ophthalmology and Visual Science 47 (2006) 2533-2541
2. Algvere P.V., Marshall J., and Seregard S. Age-related maculopathy and the impact of blue light hazard. Acta Ophthalmologica Scandinavica 84 (2006) 4-15
3. Beale R., Hall N.R., and Osborne N.N. Rat retinal cells cultured in a serum-free medium. Biochemical Society Transactions 10 (1982) 411
4. Beale R., Neuhoff N.R., and Osborne N.N. The characterisation of cell cultures of neonatal retina. In: Clayton R.M. (Ed). Problems of normal and genetically abnormal retinas (1982), Academic Press, Oxford 9-18
5. Beale R., Nicholas D., Neuhoff V., and Osborne N.N. The binding of tetanus toxin to retinal cells. Brain Research 248 (1982) 141-149
6. Berridge M.V., and Tan A.S. Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction. Archives of Biochemistry and Biophysics 303 (1993) 474-482
7. Boulton M., Rozanowska M., and Rozanowski B. Retinal photodamage. Journal of Photochemistry and Photobiology B 64 (2001) 144-161
8. Boulton M., Docchio F., Dayhaw-Barker P., Ramponi R., and Cubeddu R. Age-related changes in the morphology, absorption and fluorescence of melanosomes and lipofuscin granules of the retinal pigment epithelium. Vision Research 30 (1990) 1291-1303
9. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72 (1976) 248-254
10. Carelli V., Ross-Cisneros F.N., and Sadun A.A. Mitochondrial dysfunction as a cause of optic neuropathies. Progress in Retinal and Eye Research 23 (2004) 53-89
11. Carter W.O., Narayanan P.K., and Robinson J.P. Intracellular hydrogen peroxide and superoxide anion detection in endothelial cells. Journal of Leukocyte Biology 55 (1994) 253-258
12. Chen E. Inhibition of cytochrome oxidase and blue-light damage in rat retina. Graefes Archive for Clinical and Experimental Ophthalmology 231 (1993) 416-423
13. Chen E., Soderberg P.G., and Lindstrom B. Cytochrome oxidase activity in rat retina after exposure to 404 nm blue light. Current Eye Research 11 (1992) 825-831
14. Chen Q., Vazquez E.J., Moghaddas S., Hoppel C.L., and Lesnefsky E.J. Production of reactive oxygen species by mitochondria: central role of complex III. Journal of Biological Chemistry 278 (2003) 36027-36031
15. Egorov S.Y., Krasnovsky Jr. A.A., Bashtanov M.Y., Mironov E.A., Ludnikova T.A., et al. Photosensitization of singlet oxygen formation by pterins and flavins. Time-resolved studies of oxygen phosphorescence under laser excitation. Biochemistry (Moscow) 64 (1999) 1117-1121
16. Ernest J.T. Optic disc blood flow. Transactions of the Ophthalmological Societies of the United Kingdom 96 (1976) 348-351
17. Fink S.L., and Cookson B.T. Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells. Infection and Immunity 73 (2005) 1907-1916
18. Flammer J., and Orgul S. Optic nerve blood-flow abnormalities in glaucoma. Progress in Retinal and Eye Research 17 (1998) 267-289
19. Gavrieli Y., Sherman Y., and Ben Sasson S.A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. Journal of Cell Biology 119 (1992) 493-501
20. Godley B.F., Shamsi F.A., Liang F.Q., Jarrett S.G., Davies S., and Boulton M. Blue light induces mitochondrial DNA damage and free radical production in epithelial cells. Journal of Biological Chemistry 280 (2005) 21061-21066
21. Grunwald J.E., Piltz J., Hariprasad S.M., and DuPont J. Optic nerve and choroidal circulation in glaucoma. Investigative Ophthalmology and Visual Science 39 (1998) 2329-2336
22. Hell J.W., Maycox P.R., and Jahn R. Energy dependence and functional reconstitution of the gamma-aminobutyric acid carrier from synaptic vesicles. Journal of Biological Chemistry 265 (1990) 2111-2117
23. 2 in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America 96 (1999) 6255-6260
24. Jung J., Kim H., and Cho M. Action spectra for the generation of singlet oxygen from mitochondrial membranes from soybean (Glycine max) hypocotyls. Photochemistry and Photobiology 51 (1990) 561-566
25. Kerr J., Nelson P., and O'Brien C. A comparison of ocular blood flow in untreated primary open-angle glaucoma and ocular hypertension. American Journal of Ophthalmology 126 (1998) 42-51
26. King A., Gottlieb E., Brooks D.G., Murphy M.P., and Dunaief J.L. Mitochondria-derived reactive oxygen species mediate blue light-induced death of retinal pigment epithelial cells. Photochemistry and Photobiology 79 (2004) 470-475
27. Koeppen A.H., and Riley K.M. Effect of free malonate on the utilization of glutamate by rat brain mitochondria. Journal of Neurochemistry 48 (1987) 1509-1515
28. Kortuem K., Geiger L.K., and Levin L.A. Differential susceptibility of retinal ganglion cells to reactive oxygen species. Investigative Ophthalmology and Visual Science 41 (2000) 3176-3182
29. Kroemer G., Petit P., Zamzami N., Vayssiere J.L., and Mignotte B. The biochemistry of programmed cell death. FASEB Journal 9 (1995) 1277-1287
30. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
31. Lippold H.J. Quantitative succinic dehydrogenases histochemistry. A comparison of different tetrazolium salts. Histochemistry 76 (1982) 381-405
32. Mancini M., Nicholson D.W., Roy S., Thornberry N.A., Peterson E.P., Casciola-Rosen L.A., et al. The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling. Journal of Cell Biology 140 (1998) 1485-1495
33. Margrain T.H., Boulton M., Marshall J., and Sliney D.H. Do blue light filters confer protection against age-related macular degeneration?. Progress in Retinal and Eye Research 23 (2004) 523-531
34. Marshall J. Radiation and the ageing eye. Ophthalmic and Physiological Optics 5 (1985) 241-263
35. McConkey D.J., Orrenius S., and Jondal M. Cellular signalling in programmed cell death (apoptosis). Immunology Today 11 (1990) 120-121
36. Moragon A.C., De Lucas Garcia N., Encarnacion Lopez Fernandez M., Rodriguez-Manzaneque A.S., and Jimenez Fraile J.A. Antioxidant enzymes, occupational stress and burnout in workers of a prehospitalary emergency service. European Journal of Emergency Medicine 12 (2005) 111-115
37. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of Immunology Methods 65 (1983) 55-63
38. Noell W.K., Walker V.S., Kang B.S., and Berman S. Retinal damage by light in rats. Investigative Ophthalmology and Visual Science 5 (1966) 450-473
39. Osborne N.N., Wood J., and Groome N. The occurrence of three calcium-independent protein kinase C subspecies (delta, epsilon and zeta) in retina of different species. Brain Research 637 (1994) 156-162
40. Osborne N.N., Lascaratos G., Bron A.J., Chidlow G., and Wood J.P. A hypothesis to suggest that light is a risk factor in glaucoma and the mitochondrial optic neuropathies. British Journal of Ophthalmology 90 (2006) 237-241
41. Osborne N.N., Wood J.P.M., Chidlow G., Bae J.H., Melena J., and Nash M.S. Ganglion cell death in glaucoma: What do we really know?. British Journal of Ophthalmology 83 (1999) 980-986
42. Putting B.J., Van Best J.A., Vrensen G.F., and Oosterhuis J.A. Blue-light-induced dysfunction of the blood-retinal barrier at the pigment epithelium in albino versus pigmented rabbits. Experimental Eye Research 58 (1994) 31-40
43. Putting B.J., Zweypfenning R.C., Vrensen G.F., Oosterhuis J.A., and van Best J.A. Blood-retinal barrier dysfunction at the pigment epithelium induced by blue light. Investigative Ophthalmology and Visual Science 33 (1992) 3385-3393
44. Riordan-Eva P., Sanders M.D., Govan G.G., Sweeney M.G., Da Costa J., and Harding A.E. The clinical features of Leber's hereditary optic neuropathy defined by the presence of a pathogenic mitochondrial DNA mutation. Brain 118 Pt 2 (1995) 319-337
45. Sandbach J.M., Coscun P.E., Grossniklaus H.E., Kokoszka J.E., Newman N.J., and Wallace D.C. Ocular pathology in mitochondrial superoxide dismutase (Sod2)-deficient mice. Investigative Ophthalmology and Visual Science 42 (2001) 2173-2178
46. Seiler M.J., Liu O.L., Cooper N.G., Callahan T.L., Petry H.M., and Aramant R.B. Selective photoreceptor damage in albino rats using continuous blue light. A protocol useful for retinal degeneration and transplantation research. Graefes Archive for Clinical and Experimental Ophthalmology 238 (2000) 599-607
47. Semo M., Lupi D., Peirson S.N., Butler J.N., and Foster R.G. Light-induced c-fos in melanopsin retinal ganglion cells of young and aged rodless/coneless (rd/rd cl) mice. European Journal of Neuroscience 18 (2003) 3007-3017
48. Sievers J., Hausmann B., Unsicker K., and Berry M. Fibroblast growth factors promote the survival of adult rat retinal ganglion cells after transection of the optic nerve. Neuroscience Letters 76 (1987) 157-162
49. Sparrow J.R., Zhou J., Ben-Shabat S., Vollmer H., Itagaki Y., and Nakanishi K. Involvement of oxidative mechanisms in blue-light-induced damage to A2E-laden RPE. Investigative Ophthalmology and Visual Science 43 (2002) 1222-1227
50. Toimela T., and Tahti H. Mitochondrial viability and apoptosis induced by aluminum, mercuric mercury and methylmercury in cell lines of neural origin. Archives of Toxicology 78 (2004) 565-574
51. Towbin H., Staehelin T., and Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proceedings of the National Academy of Sciences of the United States of America 76 (1979) 4350-4354
52. van Best J.A., Putting B.J., Oosterhuis J.A., Zweypfenning R.C., and Vrensen G.F. Function and morphology of the retinal pigment epithelium after light-induced damage. Microscopy Research and Technique 36 (1997) 77-88
53. van Norren D., and Schellekens P. Blue light hazard in rat. Vision Research 30 (1990) 1517-1520
54. Votruba M. Molecular genetic basis of primary inherited optic neuropathies. Eye 18 (2004) 1126-1132
55. Wang L., Dong J., Cull G., Fortune B., and Cioffi G.A. Varicosities of intraretinal ganglion cell axons in human and nonhuman primates. Investigative Ophthalmology and Visual Science 44 (2003) 2-9
56. Wang X. The expanding role of mitochondria in apoptosis. Genes & Development 15 (2001) 2922-2933
57. Wood J., and Osborne N. Induction of apoptosis in cultured human retinal pigmented epithelial cells: the effect of protein kinase C activation and inhibition. Neurochemistry International 31 (1997) 261-274
58. Wood J.P., Chidlow G., Graham M., and Osborne N.N. Energy substrate requirements for survival of rat retinal cells in culture: the importance of glucose and monocarboxylates. Journal of Neurochemistry 93 (2005) 686-697
59. Wood J.P., Schmidt K.G., Melena J., Chidlow G., Allmeier H., and Osborne N.N. The beta-adrenoceptor antagonists metipranolol and timolol are retinal neuroprotectants: comparison with betaxolol. Experimental Eye Research 76 (2003) 505-516
60. Wyllie A.H., Kerr J.F., and Currie A.R. Cell death: the significance of apoptosis. International Review of Cytology 68 (1980) 251-306
61. Yamazaki S., Inoue Y., and Yoshikawa K. Peripapillary fluorescein angiographic findings in primary open angle glaucoma. British Journal of Ophthalmology 80 (1996) 812-817