Effects of tamoxifen and toremifene on urinary excretion of pyridinoline and deoxypyridinoline and bone density in postmenopausal patients with breast cancer

Calcified Tissue International

Volumn 65, Issue 5, 1999, Pages 365-368

  Marttunen, M B ^a   Hietanen, P ^a   Titinen, A ^a   Roth, H J ^b   Viinikka, L ^a   Ylikorkala, O ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b Laboratory Group   (Germany)

Author keywords

Breast cancer; Deoxypyridinoline; Osteoporosis; Pyridinoline; Tamoxifen; Toremifene

Indexed keywords

ANTIESTROGEN; DEOXYPYRIDINOLINE; PYRIDINOLINE; TAMOXIFEN; TOREMIFENE;

ADULT; ARTICLE; BONE DENSITY; BONE MINERAL; BREAST CANCER; CANCER ADJUVANT THERAPY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR; HUMAN; LUMBAR SPINE; OSTEOLYSIS; POSTMENOPAUSE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; URINARY EXCRETION;

AMINO ACIDS; BIOLOGICAL MARKERS; BONE DENSITY; BREAST NEOPLASMS; COHORT STUDIES; ESTROGEN ANTAGONISTS; FEMALE; HUMANS; MIDDLE AGED; POSTMENOPAUSE; TAMOXIFEN; TIME FACTORS; TOREMIFENE;

EID: 0032722761     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002239900714     Document Type: Article

References (17)

1. Calvo MS, Eyre DR, Gundberg CM (1996) Molecular basis and clinical application of biological markers of bone turnover. Endocr Rev 17:333-368
2. Uebelhart D, Schlemmer A, Johansen JS, Gineyts E, Christiansen C, Delmas P (1991) Effect of menopause and hormone replacement therapy on the urinary excretion of pyridinum cross-links. J Clin Endocrinol Metab 72:367-373
3. Ebeling PR, Atley LM, Guthrie JR, Burger HG, Dennerstein L, Hopper JL, Wark JD (1996) Bone turnover markers and bone density across the menopausal transition. J Clin Endocrinol Metab 81:3366-3371
4. Hashimoto K, Nozaki M, Inoue Y, Sano M, Nakano H (1995) The chronological change of vertebral bone loss following oophorectomy using dual energy X-ray absorptiometry: the correlation with specific markers of bone metabolism. Maturitas 22:185-192
5. Seibel MJ, Cosman F, Shen V, Gordon S, Dempster DW, Ratcliffe A, Lindsay R (1993) Urinary hydroxypyridinum crosslinks of collagen as markers of bone resorption and estrogen efficacy in postmenopausal osteoporosis. J Bone Miner Res 8:881-889
6. Garnero P, Gineyts E, Arbault P, Christiansen C, Delmas PD (1995) Different effects of bisphosphonate and estrogen therapy on free and peptide-bound bone cross-links excretion. J Bone Miner Res 10:641-649
7. Kushida K, Takahashi M, Kwana K, Inoue T (1995) Comparison of markers for bone formation and resorption in premenopausal and postmenopausal subjects, and osteoporosis patients. J Clin Endocrinol Metab 80:2447-2451
8. Howell A, Downey S, Anderson E (1996) New endocrine therapies for breast cancer. Eur J Cancer 32A:576-588
9. Kenny AM, Prestwood KM, Pilbeam CC, Raisz LG (1995) The short-term effects of tamoxifen on bone turnover in older women. J Clin Endocrinol Metab 80:3287-3291
10. Homesley HD, Shemano I, Gams RA, Harry DS, Hickox PG, Rebar RW, Bump RC, Mullin TJ, Colston Wentz A, O'Toole RV, Lovelace JV, Lyden C (1993) Antiestrogenic potency of toremifene and tamoxifen in postmenopausal women. Am J Oncol 16:117-122
11. Pyrhönen S, Valavaara R, Modig H (1997) Comparison of toremifene and tamoxifen in postmenopausal patients with advanced breast cancer: a randomized double-blind, the 'nordic' phase III study. Br J Cancer 76:270-277
12. Garnero P, Shin WJ, Gineyts E, Karpf DB, Delmas P (1994) Comparison of new biochemical markers of bone turnover in late postmenopausal osteoporotic women in response to alendronate treatment. J Clin Endocrinol Metab 79:1693-1700
13. De Boer H, Blok GJ, Van Lingen A, Teule GJJ, Lips P, Van Der Veen EA (1994) Consequences of childhood-onset growth hormone deficiency for adult bone mass. J Bone Miner Res 9:1319-1326
14. Marttunen MB, Hietanen P, Tiitinen A, Ylikorkala O (1998) Comparison of effects of tamoxifen and toremifene on bone biochemistry and bone mineral density in postmenopausal breast cancer patients. J Clin Endocrinol Metab 83:1158-1162
15. Riggs BL, Wahner HW, Melton LM III, Richelson LS, Judd HL, Offord KP (1986) Rates of bone loss in the appendicular and axial skeletons of women. J Clin Invest 77:1487-1491
16. Lindsay R (1996) The oestrogen receptor in bone - evolution of our knowledge. Br J Obst Gyn 1035:16-19
17. Väänänen HK, Härkönen PL (1996) Estrogen and bone metabolism. 23S:65-69