Sodium hydride mediated cascade reaction towards the synthesis of 1,5-disubstituted uracil from cyanamides derived from Baylis-Hillman adducts

Synthesis

Volumn , Issue 6, 2007, Pages 0911-0917

  Nag, S ^a   Yadav, G P ^a   Maulik, P R ^a   Batra, S ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

1,5 disubstituted uracil; Baylis Hillman reaction; Cascade reaction; Heterocycles; Ring closure

Indexed keywords

BAYLIS HILLMAN REACTION; CASCADE REACTION; RING CLOSURE; URACIL;

AMIDES; CHEMICAL BONDS; CYCLIZATION; ESTERS; REACTION KINETICS; SODIUM COMPOUNDS;

CRYSTAL STRUCTURE;

1 BENZYL 5 (2 CHLOROBENZYL)PYRIMIDINE 2,4(1H,3H) DIONE; 1 BENZYL 5 (2 CHLOROBENZYLIDENE) 5,6 DIHYDROPYRIMIDINE 2,4(1H,3H) DIONE 2 OXIME; 1 BENZYL 5 [METHOXY(PHENYL)METHYL] 5,6 DIHYDROPYRIMIDINE 2,4(1H,3H) DIONE 2 OXIME; 1 BENZYL 5 BENZYLIDENE 5,6 DIHYDROPYRIMIDINE 2,4(1H,3H) DIONE 2 OXIME; 1 BUTYL 5 (2 CHLOROBENZYL)PYRIMIDINE 2,4(1H,3H) DIONE; 1,5 DIBENZYLPYRIMIDINE 2,4(1H,3H) DIONE; 5 (2 CHLOROBENZYL) 1 CYCLOHEXYLPYRIMIDINE 2,4(1H,3H) DIONE; 5 (2 CHLOROBENZYLIDENE) 1 CYCLOHEXYL 5,6 DIHYDROPYRIMIDINE 2,4(1H,3H) DIONE 2 OXIME; 5 BENZYL 1 BUTYLPYRIMIDINE 2,4(1H,3H) DIONE; 5 BENZYL 1 CYCLOHEXYLPYRIMIDINE 2,4(1H,3H) DIONE; 5 BENZYL 1 PHENYLPYRIMIDINE 2,4(1H,3H) DIONE; 5 BENZYLIDENE 1 CYCLOHEXYL 5,6 DIHYDROPYRIMIDINE 2,4(1H,3H) DIONE 2 OXIME; CYANAMIDE; ETHYL 2 [(1 BENZYLUREIDO)METHYL] 3 (2 CHLOROPHENYL)ACRYLATE; ETHYL 2 [(1 BENZYLUREIDO)METHYL] 3 PHENYLACRYLATE; ETHYL 2 [(BENZYLAMINO)METHYL] 3 (2 CHLOROPHENYL) 3 HYDROXYPROPIONATE; ETHYL 2 [[BENZYL(CYANO)AMINO]METHYL] 3 (2 CHLOROPHENYL) 3 HYDROXYPROPIONATE; ETHYL 2 [[BENZYL(CYANO)AMINO]METHYL] 3 HYDROXY 3 PHENYL PROPIONATE; ETHYL 2 [[BUTYL(CYANO)AMINO]METHYL] 3 (2 CHLOROPHENYL) 3 HYDROXYPROPIONATE; ETHYL 2 [[CYANO(CYCLOHEXYL)AMINO]METHYL] 3 HYDROXY 3 PHENYLPROPIONATE; METHYL 2 [(1 BENZYLUREIDO)METHYL] 3 PHENYLACRYLATE; UNCLASSIFIED DRUG; URACIL;

ARTICLE; BAYLIS HILLMAN REACTION; CYCLIZATION; MOLECULAR MECHANICS; REACTOR CASCADE; SUBSTITUTION REACTION;

EID: 33947591173     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-965931     Document Type: Article

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