A liquid chromatography-mass spectrometry assay method for simultaneous determination of amiodarone and desethylamiodarone in rat specimens

Biomedical Chromatography

Volumn 21, Issue 3, 2007, Pages 284-290

  Shayeganpour, Anooshirvan ^a   Somayaji, Vishwa ^a   Brocks, Dion R ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Amiodarone; Antiarrhythmics; LC MS; Pharmacokinetics

Indexed keywords

DRUG PRODUCTS; KETONES; LIQUID CHROMATOGRAPHY; RATS; TISSUE; TISSUE ENGINEERING;

AMIODARONE; ANALYTES; ANTIARRHYTHMIC; ASSAY METHODS; LIQUID CHROMATOGRAPHIC-MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; LIQUID-LIQUID EXTRACTION; MICROMASS; SIMULTANEOUS DETERMINATIONS; SPECTROMETRY SYSTEMS;

MASS SPECTROMETRY;

AMIODARONE; DEETHYLAMIODARONE; DRUG METABOLITE; FORMIC ACID; HEXANE; METHANOL; PROFENAMINE; SABEX; UNCLASSIFIED DRUG;

ANALYTICAL ERROR; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG STRUCTURE; DRUG TISSUE LEVEL; ELUTION; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; MASS SPECTROMETRY; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; SEPARATION TECHNIQUE; VALIDATION PROCESS;

RATTUS;

EID: 33947588884     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.754     Document Type: Article

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