Chronic thyroxine treatment activates the 5-HT2A serotonin receptor in the mouse brain

Neuroscience Letters

Volumn 416, Issue 3, 2007, Pages 307-309

  Kulikov, A V ^a   Zubkov, E A ^b  

^a INSTITUTE OF CYTOLOGY AND GENETICS   (Russian Federation)

^b NOVOSIBIRSK STATE UNIVERSITY   (Russian Federation)

Author keywords

5 HT2A receptor mRNA; DOI induced head twitch; Mice; Thyroxine

Indexed keywords

4 IODO 2,5 DIMETHOXYAMPHETAMINE; MESSENGER RNA; SEROTONIN 2A RECEPTOR; THYROID HORMONE; THYROXINE;

AKR MOUSE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FRONTAL CORTEX; HEAD TWITCH; LONG TERM CARE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR GENE; REGULATORY MECHANISM;

AMPHETAMINES; ANALYSIS OF VARIANCE; ANIMALS; BRAIN; DRUG ADMINISTRATION SCHEDULE; DRUG INTERACTIONS; GENE EXPRESSION REGULATION; MALE; MICE; MICE, INBRED AKR; RECEPTOR, SEROTONIN, 5-HT2A; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEROTONIN AGONISTS; THYROXINE;

EID: 33947588840     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.02.018     Document Type: Article

References (20)

1. Barnes N., and Sharp T. A review of central 5-HT receptors and their function. Neuropharmacology 38 (1999) 1083-1152
2. Barykina N.N., Chuguy V.F., Alekhina T.A., Kolpakov V.G., Maksiutova A.V., and Kulikov A.V. Effects of thyroid hormone deficiency on behavior in rat strains with different predisposition to catalepsy. Physiol. Behav. 75 (2002) 733-737
3. Bauer M., and Whybrow P.C. Rapid cycling bipolar affective disorders. II. Treatment of refractory rapid cycling with high-dose levothyroxine: a preliminary study. Arch. Gen. Psychiatry 47 (1990) 435-440
4. Bauer M., Heinz A., and Whybrow P.C. Thyroid hormones, serotonin and mood: of synergy and significance in the adult brain. Mol. Psychiatry 7 (2002) 140-156
5. Bauer M., London E.D., Silverman D.H.S., Rasgon N., Kirchheiner J., and Whybrow P.C. Thyroid, bran and mood modulation in affective disorder: insights from molecular research and functional brain imaging. Pharmacopsychiatry 36 (2003) S215-S221
6. Clear A.J., McGregor A., Chambers S.M., Dawling S., and O'Keane V. Thyroxine replacement increases central 5-hydroxytryptamine activity and reduces depressive symptoms in hypothyroidism. Neuroendocrinology 64 (1996) 65-69
7. 2A receptors: a review of in vivo studies. Behav. Brain Res. 73 (1996) 177-181
8. 2 sites in cortex and amygdala. Brain Res. 614 (1993) 37-44
9. Joffe R.T., Sokolov T.H., and Singer W. Thyroid hormone treatment of depression. Thyroid 5 (1995) 235-239
10. Kirkegaard C., and Faber J. The role of thyroid hormones in depression. Eur. J. Endocrinol. 138 (1998) 1-9
11. Kulikov A.V., Maksyutova A.V., Ivanova E.A., Khvorostov I.B., and Popova K.N. The effect of thyroidectomy on the expression of the mRNA of 5-HT2A serotonin receptors in the rat frontal cortex. Dokld. Biochem. Biophys. 383 (2002) 116-118
12. 2A uptake sites and tryptophan hydroxilase activity in mature rat brain. Neuroendocrinology 69 (1999) 453-459
13. 2A serotonin receptor mRNA using genomic DNA as an external standard. J. Neurosci. Methods 141 (2005) 97-101
14. 2 receptors, roles and regulation. Ann. N.Y. Acad. Sci. 600 (1990) 183-191
15. Muller Y., and Closs J. L'hormone thyroidienne est-elle un donneur de temps au cours du developpement du system nerveux central. Medecine/Sciences 13 (1997) 116-122
16. Musselman D.L., and Nemeroff C.B. Depression and endocrine disorders: focus on the thyroid and adrenal system. Br. J. Psychiatry 168 (1996) 123-128
17. Pandey G.N., Dwivedi Y., Rizavi H.S., Ren X., Pandey S.C., Pesold C., Roberts R.C., Conley R.R., and Tamminga C.A. Higher expression of serotonin 5-HT2A receptors in the postmortem brains of teenage suicide victims. Am. J. Psychiatry 159 (2002) 419-429
18. Prange A.J. Novel uses of thyroid hormones in patient with affective disorders. Thyroid 6 (1996) 537-543
19. Ruiz-Marcos A., Sanches-Toskano F., Escobar del Rey F., and Morreale de Escobar G. Reversible morphological alteration of cortical neurons in juvenile and adult hypothyroidism in the rat. Brain Res. 185 (1980) 91-102
20. 2A receptors and behavior in rats with experimental thyroid disturbances. Pharmacol. Biochem. Behav. 82 (2005) 506-514