Prevalence of Toxocara-induced liver granulomas, detected by immunohistochemistry, in a series of autopsies at a Children's Reference Hospital in Vitoria, ES, Brazil

Virchows Archiv

Volumn 450, Issue 4, 2007, Pages 411-417

  Musso, Carlos ^a   Castelo, Jane S ^b   Tsanaclis, Ana M C ^c   Pereira, Fausto E L ^a  

^a FEDERAL UNIVERSITY OF ESPÍRITO SANTO   (Brazil)

^b Hospital Infantil NS da Gloria   (Brazil)

^c UNIVERSITÉ DE SHERBROOKE   (Canada)

Author keywords

Eosinophil rich granulomas; Hepatic granulomas; Toxocara; Toxocariasis; Visceral larva migrans

Indexed keywords

ADOLESCENT; ANTIBODY DETECTION; ANTIGEN DETECTION; ARTICLE; AUTOPSY; CHILD; CONTROLLED STUDY; EPITHELIOID CELL; FEMALE; GIANT CELL; GRANULOMATOUS HEPATITIS; HOSPITAL ADMISSION; HUMAN; IMMUNOHISTOCHEMISTRY; INFANT; INFECTION PREVENTION; LIVER GRANULOMA; MALE; MORBIDITY; PRIORITY JOURNAL; SEROLOGY; STAINING; TOXOCARA; VISCERAL LARVA MIGRANS SYNDROME;

ADOLESCENT; ANIMALS; AUTOPSY; BRAZIL; CHILD; CHILD, PRESCHOOL; FEMALE; GRANULOMA; HUMANS; IMMUNE SERA; IMMUNOHISTOCHEMISTRY; INFANT; LARVA MIGRANS, VISCERAL; LIVER DISEASES; MALE; PREVALENCE; RABBITS; TOXOCARA; TOXOCARA CANIS;

EID: 33947525999     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-007-0388-5     Document Type: Article

References (19)

1. Beaver PC (1956) Larva migrans. Exp Parasitol 5:587-621
2. Chandrashekar R, Curtis KC, Weil GJ (1995) Molecular characterization of a parasite antigen in sera from onchocerciasis patients that is immunologically cross-reactive with human keratin. J Infect Dis 171:1586-1592
3. De Brito T, Chieffi PP, Peres BA, Santos RP, Gayotto LCC, Vianna MR, Porta G, Alves VA (1994) Immunohistochemical detection of Toxocara antigen in human biopsies. Int J Surg Pathol 2:117-124
4. Despommier D (2003) Toxocariasis: clinical aspects, epidemiology, medical ecology, and molecular aspects. Clin Microbiol Rev 16:265-272
5. Fuchs E, Marchuk D (1983) Type I and type II keratins have evolved from lower eukaryotes to form the epidermal intermediate filaments in mammalian skin. Proc Natl Acad Sci USA 80:5857-5861
6. Gems D, Ferguson CJ, Robertson BD, Nieves R, Page AP, Blaxter ML, Maizels RM (1995) An abundant, trans-spliced mRNA from Toxocara canis infective larvae encodes a 26-kDa protein with homology to phosphatidylethanolamine- binding proteins. Biol Chem 270:18517-18522
7. Kaplan KJ, Goodman ZD, Ishak KG (2001) Eosinophilic granuloma of the liver: a characteristic lesion with relationship to visceral larva migrans. Am J Surg Pathol 25:1316-1321
8. Masuoka J, Guthrie LN, Hazen KC (2002) Complications in cell-surface labelling by biotinylation of Candida albicans due to avidin conjugate binding to cell-wall proteins. Microbiology 148 (Pt 4):1073-1090
9. Moreira-Silva SF, Leao ME, Mendonca HF, Pereira FE (1998) Prevalence of anti-Toxocara antibodies in a random sample of inpatients at a children's hospital in Vitoria, Espirito Santo, Brazil. Rev Inst Med Trop Sao Paulo 40:259-261
10. Moreira-Silva SF, Leite AL, Brito EF, Pereira FE (2002) Nematode infections are risk factors for staphylococcal infection in children. Mem Inst Oswaldo Cruz 97:395-399
11. Moreira-Silva SF, Pereira FE (2000) Intestinal nematodes, Toxocara infection, and pyogenic liver abscess in children: a possible association. J Trop Pediatr 46:167-172
12. Musso C, Lemos EM, Tsanaclis AMC, Pereira FEL (2006) Toxocara infection is not associated with viral or bacterial central nervous system infection in children. Neuropediatrics 37:126-129
13. Musso C, Castelo JS, Tsanaclis AMC, Pereira FE (2006) Visceral larva migrans granulomas in liver and central nervous system of children who died of bacterial or viral meningitis. Clin Neuropathol 25:288-290
14. Nichols RL (1956) The etiology of visceral larva migrans. I. Diagnostic morphology of infective second-stage Toxocara larvae. J Parasitol 42:349-362
15. Pawlowski Z (2001) Toxocariasis in humans: clinical expression and treatment dilemma. J Helminthol 75(4):299-305
16. Pereira FE, Musso C, Castelo JS (1999) Pathology of pyogenic liver abscess in children. Pediatr Dev Pathol 2:537-543
17. Salfelder K, De Liscano TR, De Mendelovici M (1973) Visceral eosinophilic granulomas. Beitr Pathol 149:420-428
18. Smith HV, Quinn R, Bruce RG, Girdwood WA (1982) Development of the serological response in rabbits infected with Toxocara canis and Toxascaris leonina. Trans R Soc Trop Med Hyg 76:89-94
19. Taylor MR, Keane CT, O'Connor P, Mulvihill E, Holland C (1988) The expanded spectrum of toxocaral disease. Lancet 1:692-695