Peptides derived from the C2 domain of protein kinase Cε (εPKC) modulate εPKC activity and identify potential protein-protein interaction surfaces

Journal of Biological Chemistry

Volumn 282, Issue 6, 2007, Pages 4113-4123

  Brandman, Relly ^a   Disatnik, Marie Hélène ^a   Churchill, Eric ^a   Mochly Rosen, Daria ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C2 DOMAIN; HEART TRANSPLANTATION; ISCHEMIC DAMAGE; ISOZYME-SELECTIVE ACTIVATOR; PKC-MODULATING ACTIVITIES; PROTEIN-PROTEIN INTERACTION SURFACES;

AMINO ACIDS; CARDIOVASCULAR SYSTEM; DISEASE CONTROL; ENZYME INHIBITION; MEDICAL PROBLEMS; PHOSPHORYLATION;

PEPTIDES;

ALANINE; ISOENZYME; PROTEIN KINASE C ACTIVATOR; PROTEIN KINASE C EPSILON; PROTEIN KINASE C EPSILON[112 118]; PROTEIN KINASE C EPSILON[119 124]; PROTEIN KINASE C EPSILON[125 131]; PROTEIN KINASE C EPSILON[14 21]; PROTEIN KINASE C EPSILON[28 35]; PROTEIN KINASE C EPSILON[36 41]; PROTEIN KINASE C EPSILON[4 12]; PROTEIN KINASE C EPSILON[40 47]; PROTEIN KINASE C EPSILON[49 53]; PROTEIN KINASE C EPSILON[54 60]; PROTEIN KINASE C EPSILON[62 67]; PROTEIN KINASE C EPSILON[68 73]; PROTEIN KINASE C EPSILON[74 79]; PROTEIN KINASE C EPSILON[79 84]; PROTEIN KINASE C EPSILON[85 92]; PROTEIN KINASE C INHIBITOR; UNCLASSIFIED DRUG; PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHO CELL; CONTROLLED STUDY; DRUG EFFECT; DRUG SELECTIVITY; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; EX VIVO STUDY; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART PROTECTION; IN VIVO STUDY; MOUSE; MYRISTYLATION; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RAT; STRUCTURE ACTIVITY RELATION; AMINO ACID SEQUENCE; ANIMAL; CELL CULTURE; CRICETULUS; DISEASE MODEL; ENZYME SPECIFICITY; ENZYMOLOGY; HAMSTER; METABOLISM; MOLECULAR GENETICS; MOUSE MUTANT; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN ANALYSIS; PROTEIN TERTIARY STRUCTURE; SYNTHESIS; WISTAR RAT;

MUS;

AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; CHO CELLS; CRICETINAE; CRICETULUS; DISEASE MODELS, ANIMAL; ISOENZYMES; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; MYOCARDIAL ISCHEMIA; PEPTIDES; PHOSPHORYLATION; PROTEIN INTERACTION MAPPING; PROTEIN KINASE C-EPSILON; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RATS; RATS, WISTAR; SUBSTRATE SPECIFICITY;

EID: 33947522817     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M608521200     Document Type: Article

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