VEGF165 gene-mediated arteriogenesis and cardioprotection in large mammals with acute myocardial infarction. Confirmation of previous results from other authors

Circulation Research

Volumn 100, Issue 4, 2007, Pages

  Crottogini, Alberto ^a   Laguens, Rubén ^a  

^a FAVALORO UNIVERSITY   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; PLASMID DNA; VASCULOTROPIN 165; CARDIOTONIC AGENT; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL GROWTH FACTOR A, HUMAN; VASCULOTROPIN A;

ANGIOGENESIS; APOPTOSIS; CELL PROLIFERATION; CELL VIABILITY; CYTOKINESIS; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; GENE EXPRESSION; GENE TRANSFER; HEART INFARCTION; HEART PROTECTION; LETTER; MITOSIS; MITOSIS INDEX; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; TISSUE REPAIR; UPREGULATION; VIRAL GENE THERAPY; ANIMAL; ARTERIOLE; CYTOLOGY; DOG; GENE THERAPY; GENETICS; GROWTH, DEVELOPMENT AND AGING; HEART MUSCLE CELL; HUMAN; METABOLISM; METHODOLOGY; NOTE; PHYSIOLOGY;

ANIMALS; ARTERIOLES; CARDIOTONIC AGENTS; DOGS; GENE THERAPY; HUMANS; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33947517101     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000259103.78029.09     Document Type: Letter

References (5)

1. Ferrarini M, Arsic N, Recchia FA, Zentilin L, Zacchigna S, Xu X, Linke A, Giacca M, Hintze TH. Adeno-associated virus-mediated tansduction of VEGF165 improves cardiac tissue viability and functional recovery after permanent coronary occlusion in conscious dogs. Circ Res. 2006;98:954-961.
2. Crottogini A, Meckert PC, Vera Janavel G, Lascano E, Negroni J, Del Valle H, Dulbecco E, Werba P, Cuniberti L, Martinez V, De Lorenzi A, Telayna J, Mele A, Fernandez JL, Marangunich L, Criscuolo M, Capogrossi MC, Laguens R. Arteriogenesis induced by intramyocardial vascular endothelial growth factor 165 gene transfer in chronically ischemic pigs. Hum Gene Ther. 2003;14:1307-1318.
3. Laguens R, Cabeza Meckert P, Vera Janavel G, Del Valle H, Lascano E, Negroni J, Werba P, Cuniberti L, Martinez V, Melo C, Papouchado M, Ojeda R, Criscuolo M, Crottogini A. Entrance in mitosis of adult cardiomyocytes in ischemic pig hearts after plasmid-mediated rhVEGF165 gene transfer. Gene Ther. 2002;9:1676-1681.
4. Laguens R, Cabeza Meckert P, Vera Janavel G, De Lorenzi A, Lascano E, Negroni J, Del Valle H, Cuniberti L, Martinez V, Dulbecco E, Melo C, Fernandez N, Criscuolo M, Crottogini A. Cardiomyocyte hyperplasia after plasmid-mediated vascular endothelial growth factor gene transfer in pigs with chronic myocardial ischemia. J Gene Med. 2004;6:222-227.
5. Vera Janavel G, Crottogini A, Cabeza Meckert P, Cuniberti L, Mele A, Papouchado M, Fernandez N, Bercovich A, Criscuolo M, Melo C, Laguens R. Plasmid-mediated VEGF gene transfer induces cardiomyogenesis and reduces myocardial infarct size in sheep. Gene Ther. 2006;13:1133-1142.