Analysis of the -844C > T polymorphism in the promoter region of FASLgene in a cohort of Spanish HCV patients

Journal of Viral Hepatitis

Volumn 14, Issue 4, 2007, Pages 293-294

  Ruiz Ferrer, M ^a   Antinolo G ^a   Aguilar Reina, J ^a  

^a HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

Author keywords

Apoptosis; Genetics; Hepatitis C virus infection; Susceptibility factor

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; FAS LIGAND; GAMMA INTERFERON; STAT1 PROTEIN;

COHORT ANALYSIS; CONTROLLED STUDY; GENE EXPRESSION; GENE FREQUENCY; GENETIC SUSCEPTIBILITY; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN TISSUE; LETTER; LIVER BIOPSY; MAJOR CLINICAL STUDY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM;

APOPTOSIS; FAS LIGAND PROTEIN; FEMALE; HEPACIVIRUS; HEPATITIS C; HUMANS; LIVER CIRRHOSIS; MALE; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS);

EID: 33947406875     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/j.1365-2893.2006.00821.x     Document Type: Letter

References (10)

1. Poynard T, Bedossa P, Opolon P. Natural history of liver fibrosis progression in patients with chronic hepatitis C. Lancet 1997; 349: 825-832.
2. Hayashi N, Mita E. Fas system and apoptosis in viral hepatitis. J Gastroenterol Hepatol 1997; 12: 223-226.
3. Hiramatsu N, Hayashi N, Katayama K et al. Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis C. Hepatology 1994; 19: 1354-1359.
4. Suda T, Takahashi T, Golstein P, Nagata S. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 1993; 75: 1169-1178.
5. Aguilar-Reina J, Ruiz-Ferrer M, Pizarro MA, Antinolo G. The -670A > G polymorphism in the promoter region of the FAS gene is associated with necrosis in periportal areas in patients with chronic hepatitis C. J Viral Hepat 2005; 12: 568-573.
6. Huang QR, Morris D, Manolios N. Identification and characterization of polymorphisms in the promoter region of the human Apo-1/Fas (CD95) gene. Mol Immunol 1997; 34: 577-582.
7. Wu J, Metz C, Xu X et al. A novel polymorphic CAAT/enhancer- binding protein beta element in the FasL gene promoter alters Fas ligand expression: a candidate background gene in African American systemic lupus erythematosus patients. J Immunol 2003; 170: 132-138.
8. Knodell RG, Ishak KG, Black WC et al. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1981; 1: 431-435.
9. Dracapoly NH, Seidman CE, Seidman JG, Smith DR. Current Protocols in Human Genetics, Vol. 1. New York: John Wilet & Sons, 1996.
10. Ramji DP, Foka P. CCAAT/enhancer-binding proteins: structure, function and regulation. Biochem J 2002; 365: 561-575.