Low-dose recombinant activated factor VII in massively transfused trauma patients with coagulopathy [4]

Transfusion

Volumn 47, Issue 4, 2007, Pages 749-751

  Bauzá, Graciela ^a   Hirsch, Erwin ^a   Burke, Peter ^a   Quillen, Karen ^a  

^a BOSTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FRESH FROZEN PLASMA; RECOMBINANT BLOOD CLOTTING FACTOR 7A;

ADOLESCENT; ADULT; AGED; BLEEDING; BLOOD CLOTTING DISORDER; BLOOD TRANSFUSION; BLUNT TRAUMA; CLINICAL ARTICLE; ERYTHROCYTE TRANSFUSION; FALLING; HEART INFARCTION; HEMOSTASIS; HUMAN; INJURY SEVERITY; INTERNATIONAL NORMALIZED RATIO; KIDNEY INJURY; LETTER; LIVER INJURY; LOW DRUG DOSE; LUNG INJURY; PELVIS FRACTURE; PLASMA TRANSFUSION; POSTOPERATIVE HEMORRHAGE; PROTHROMBIN TIME; SPLEEN INJURY; THROMBOCYTE TRANSFUSION; TRAFFIC ACCIDENT; TREATMENT INDICATION;

ADOLESCENT; ADULT; AGED; BLOOD COAGULATION DISORDERS; BLOOD COMPONENT TRANSFUSION; DOSE-RESPONSE RELATIONSHIP, DRUG; FACTOR VII; FACTOR VIIA; HEMORRHAGE; HUMANS; INTERNATIONAL NORMALIZED RATIO; MIDDLE AGED; RECOMBINANT PROTEINS; TIME FACTORS; TREATMENT OUTCOME; WOUNDS AND INJURIES;

EID: 33947386217     PISSN: 00411132     EISSN: 15372995     Source Type: Journal    
DOI: 10.1111/j.1537-2995.2007.01182.x     Document Type: Letter

References (6)

1. Boffard KD, Riou B, Warren B, et al. Recombinant factor VIIa as adjunctive therapy for bleeding control in severely injured trauma patients: two parallel randomized, placebo-controlled, double-blind clinical trials. J Trauma 2005;59:8-16.
2. Harrison TD, Laskosky J, Jazaeri O, et al. "Low-dose" recombinant activated factor VII results in less blood and blood product use in traumatic hemorrhage. J Trauma 2005;59:150-4.
3. Mariani G, Testa MG, Di PT, et al. Use of recombinant, activated factor VII in the treatment of congenital factor VII deficiencies. Vox Sang 1999;77:131-6.
4. Deveras RA, Kessler CM. Reversal of warfarin-induced excessive anticoagulation with recombinant human factor VIIa concentrate. Ann Intern Med 2002;137:884-8.
5. Friederich PW, Henny CP, Messelink EJ, et al. Effect of recombinant activated factor VII on perioperative blood loss in patients undergoing retropubic prostatectomy: a double-blind placebo-controlled randomised trial. Lancet 2003;361:201-5.
6. Romagnoli S, Bevilacqua S, Gelsomino S, et al. Small-dose recombinant activated factor VII in cardiac surgery. Anesth Analg 2006;102:1320-6.