-
1
-
-
25144488564
-
Approval summary for erlotinib for treatment of patients with locally advanced or metastatic non-small cell lung cancer after failure of at least one prior chemotherapy regimen
-
Johnson JR, Cohen M, Sridhara R, et al. Approval summary for erlotinib for treatment of patients with locally advanced or metastatic non-small cell lung cancer after failure of at least one prior chemotherapy regimen. Clin Cancer Res 2005;11:6414-21.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6414-6421
-
-
Johnson, J.R.1
Cohen, M.2
Sridhara, R.3
-
2
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
Shepherd FA, Rodrigues Pereira J, Ciuleanu T, et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005;353:123-32.
-
(2005)
N Engl J Med
, vol.353
, pp. 123-132
-
-
Shepherd, F.A.1
Rodrigues Pereira, J.2
Ciuleanu, T.3
-
3
-
-
1842772526
-
Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck
-
Soulieres D, Senzer NN, Vokes EE, Hidalgo M, Agarwala SS, Siu LL. Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck. J Clin Oncol 2004;22:77-85.
-
(2004)
J Clin Oncol
, vol.22
, pp. 77-85
-
-
Soulieres, D.1
Senzer, N.N.2
Vokes, E.E.3
Hidalgo, M.4
Agarwala, S.S.5
Siu, L.L.6
-
4
-
-
27244447373
-
Phase II study of erlotinib (OSI-774) in patients with advanced hepatocellular cancer
-
Philip PA, Mahoney MR, Allmer C, et al. Phase II study of erlotinib (OSI-774) in patients with advanced hepatocellular cancer. J Clin Oncol 2005;23:6657-63.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6657-6663
-
-
Philip, P.A.1
Mahoney, M.R.2
Allmer, C.3
-
5
-
-
28944439741
-
Efficacy and safety of erlotinib HCl, an epidermal growth factor receptor (HER1/EGFR) tyrosine kinase inhibitor, in patients with advanced ovarian carcinoma: Results from a phase II multicenter study
-
Gordon AN, Finkler N, Edwards RP, et al. Efficacy and safety of erlotinib HCl, an epidermal growth factor receptor (HER1/EGFR) tyrosine kinase inhibitor, in patients with advanced ovarian carcinoma: results from a phase II multicenter study. Int J Gynecol Cancer 2005;15:785-92.
-
(2005)
Int J Gynecol Cancer
, vol.15
, pp. 785-792
-
-
Gordon, A.N.1
Finkler, N.2
Edwards, R.P.3
-
6
-
-
31544474851
-
Phase 1 study of erlotinib HCL alone and combined with temozolomide in patients with stable or recurrent malignant glioma
-
Prados MD, Lamborn KR, Chang S, et al. Phase 1 study of erlotinib HCL alone and combined with temozolomide in patients with stable or recurrent malignant glioma. Neuro-oncol 2006;8:67-78.
-
(2006)
Neuro-oncol
, vol.8
, pp. 67-78
-
-
Prados, M.D.1
Lamborn, K.R.2
Chang, S.3
-
7
-
-
33646143020
-
Phase II study of erlotinib (OSI-774) in patients with metastatic colorectal cancer
-
Townsley CA, Major P, Siu LL, et al. Phase II study of erlotinib (OSI-774) in patients with metastatic colorectal cancer. Br J Cancer 2006;94:1136-43.
-
(2006)
Br J Cancer
, vol.94
, pp. 1136-1143
-
-
Townsley, C.A.1
Major, P.2
Siu, L.L.3
-
8
-
-
33745970752
-
Phase II study of erlotinib in patients with advanced biliary cancer
-
Philip PA, Mahoney MR, Allmer C, et al. Phase II study of erlotinib in patients with advanced biliary cancer. J Clin Oncol 2006;24:3069-74.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3069-3074
-
-
Philip, P.A.1
Mahoney, M.R.2
Allmer, C.3
-
9
-
-
0035398631
-
Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies
-
Hidalgo M, Siu LL, Nemunaitis J, et al. Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies. J Clin Oncol 2001;19:3267-79.
-
(2001)
J Clin Oncol
, vol.19
, pp. 3267-3279
-
-
Hidalgo, M.1
Siu, L.L.2
Nemunaitis, J.3
-
10
-
-
4143149763
-
Evaluation of biologic end points and pharmacokinetics in patients with metastatic breast cancer after treatment with erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor
-
Tan AR, Yang X, Hewitt SM, et al. Evaluation of biologic end points and pharmacokinetics in patients with metastatic breast cancer after treatment with erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor. J Clin Oncol 2004;22:3080-90.
-
(2004)
J Clin Oncol
, vol.22
, pp. 3080-3090
-
-
Tan, A.R.1
Yang, X.2
Hewitt, S.M.3
-
11
-
-
33344461165
-
Metabolism and excretion of erlotinib, a small molecule inhibitor of epidermal growth factor receptor tyrosine kinase, in healthy male volunteers
-
Ling J, Johnson KA, Miao Z, et al. Metabolism and excretion of erlotinib, a small molecule inhibitor of epidermal growth factor receptor tyrosine kinase, in healthy male volunteers. Drug Metab Dispos 2006; 34:420-6.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 420-426
-
-
Ling, J.1
Johnson, K.A.2
Miao, Z.3
-
12
-
-
27744506881
-
Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: Tissue analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01
-
Lassman AB, Rossi MR, Raizer JJ, et al. Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: tissue analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01. Clin Cancer Res 2005;11:7841-50.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7841-7850
-
-
Lassman, A.B.1
Rossi, M.R.2
Raizer, J.J.3
-
13
-
-
0142059544
-
Specific method for determination of OSI-774 and its metabolite OSI-420 in human plasma by using liquid chromatography-tandem mass spectrometry
-
Zhao M, He P, Rudek MA, Hidalgo M, Baker SD. Specific method for determination of OSI-774 and its metabolite OSI-420 in human plasma by using liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2003; 793:413-20.
-
(2003)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.793
, pp. 413-420
-
-
Zhao, M.1
He, P.2
Rudek, M.A.3
Hidalgo, M.4
Baker, S.D.5
-
15
-
-
0004062826
-
-
University of Southern California. Los Angeles: Biomedical Simulation Resource;
-
D'Argenio DZ, Schumitzky A. ADAPT II User's Guide, University of Southern California. Los Angeles: Biomedical Simulation Resource; 1990.
-
(1990)
ADAPT II User's Guide
-
-
D'Argenio, D.Z.1
Schumitzky, A.2
-
16
-
-
0030774045
-
Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase
-
Moyer JD, Barbacci EG, Iwata KK, et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res 1997;57:4838-48.
-
(1997)
Cancer Res
, vol.57
, pp. 4838-4848
-
-
Moyer, J.D.1
Barbacci, E.G.2
Iwata, K.K.3
-
17
-
-
0037224320
-
ERBB2 up-regulates S100A4 and several other prometastatic genes in medulloblastoma
-
Hernan R, Fasheh R, Calabrese C, et al. ERBB2 up-regulates S100A4 and several other prometastatic genes in medulloblastoma. Cancer Res 2003;63: 140-8.
-
(2003)
Cancer Res
, vol.63
, pp. 140-148
-
-
Hernan, R.1
Fasheh, R.2
Calabrese, C.3
-
18
-
-
19944427851
-
Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer
-
Amann J, Kalyankrishna S, Massion PP, et al. Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer. Cancer Res 2005;65:226-35.
-
(2005)
Cancer Res
, vol.65
, pp. 226-235
-
-
Amann, J.1
Kalyankrishna, S.2
Massion, P.P.3
-
19
-
-
30844446711
-
Complete response to erlotinib treatment in brain metastases from recurrent NSCLC
-
Lai CS, Boshoff C, Falzon M, Lee SM. Complete response to erlotinib treatment in brain metastases from recurrent NSCLC. Thorax 2006;61:91.
-
(2006)
Thorax
, vol.61
, pp. 91
-
-
Lai, C.S.1
Boshoff, C.2
Falzon, M.3
Lee, S.M.4
-
20
-
-
4143110253
-
Gefitinib in patients with brain metastases from non-small-cell lung cancer: A prospective trial
-
Ceresoli GL, Cappuzo F, Gregorc V, Bartolini S, Crino L, Villa E. Gefitinib in patients with brain metastases from non-small-cell lung cancer: a prospective trial. Ann Oncol 2004;15:1042-7.
-
(2004)
Ann Oncol
, vol.15
, pp. 1042-1047
-
-
Ceresoli, G.L.1
Cappuzo, F.2
Gregorc, V.3
Bartolini, S.4
Crino, L.5
Villa, E.6
-
21
-
-
17144385106
-
Gefitinib as a first-line therapy of advanced or metastatic adenocarcinoma of the lung in never-smokers
-
Lee DH, Han JY, Lee HG, et al. Gefitinib as a first-line therapy of advanced or metastatic adenocarcinoma of the lung in never-smokers. Clin Cancer Res 2005;11: 3032-7.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 3032-3037
-
-
Lee, D.H.1
Han, J.Y.2
Lee, H.G.3
-
22
-
-
33744481276
-
EGFR mutations in patients with brain metastases from lung cancer: Association with the efficacy of gefitinib
-
Shimato S, Mitsudomi T, Kosaka T, et al. EGFR mutations in patients with brain metastases from lung cancer: association with the efficacy of gefitinib. Neuro-oncol 2006;8:137-44.
-
(2006)
Neuro-oncol
, vol.8
, pp. 137-144
-
-
Shimato, S.1
Mitsudomi, T.2
Kosaka, T.3
-
23
-
-
33745183568
-
Phase I trial of erlotinib with radiation therapy in patients with glioblastoma multiforme: Results of North Central Cancer Treatment Group protocol NO177
-
Krishnan S, Brown PD, Ballman KV, et al. Phase I trial of erlotinib with radiation therapy in patients with glioblastoma multiforme: results of North Central Cancer Treatment Group protocol NO177. Int J Radiat Oncol Biol Phys 2006;65: 1192-9.
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.65
, pp. 1192-1199
-
-
Krishnan, S.1
Brown, P.D.2
Ballman, K.V.3
-
24
-
-
33746807790
-
Pilot study of the combination of EGFR and mTOR inhibitors in recurrent malignant gliomas
-
Doherty L, Gigas DC, Kesari S, et al. Pilot study of the combination of EGFR and mTOR inhibitors in recurrent malignant gliomas. Neurology 2006;67: 156-8.
-
(2006)
Neurology
, vol.67
, pp. 156-158
-
-
Doherty, L.1
Gigas, D.C.2
Kesari, S.3
-
25
-
-
0032767387
-
Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials
-
Wong ET, Hess KR, Gleason MJ, et al. Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials. J Clin Oncol 1999;8:2572-8.
-
(1999)
J Clin Oncol
, vol.8
, pp. 2572-2578
-
-
Wong, E.T.1
Hess, K.R.2
Gleason, M.J.3
-
26
-
-
1842500007
-
Phase II trial of gefitinib in recurrent glioblastoma
-
Rich JN, Reardon DA, Peery T, et al. Phase II trial of gefitinib in recurrent glioblastoma. J Clin Oncol 2004; 22:133-42.
-
(2004)
J Clin Oncol
, vol.22
, pp. 133-142
-
-
Rich, J.N.1
Reardon, D.A.2
Peery, T.3
|