Adenoviral transduction is more efficient in alginate-derived chondrocytes than in monolayer chondrocytes

Cell and Tissue Research

Volumn 328, Issue 2, 2007, Pages 383-390

  Oberholzer, A ^a   John, T ^a   Kohl, B ^a   Gust, T ^a   Muller R D ^a   La Face, D ^c   Hutchins, B ^c   Zreiqat, H ^b   Ertel, W ^a   Schulze Tanzil, G ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF SYDNEY   (Australia)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

v 5 Integrin; Adenovirus; Chondrocyte; Collagen type II; Green fluorescence protein gene; Human

Indexed keywords

ADENOVIRUS VECTOR; ALGINIC ACID; ALPHAVBETA5 INTEGRIN; COLLAGEN TYPE 5; ENHANCED GREEN FLUORESCENT PROTEIN; INTEGRIN RECEPTOR; PROTEOGLYCAN; SCLEROPROTEIN;

ARTICLE; CARTILAGE; CARTILAGE CELL; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; MONOLAYER CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE REPAIR; VIRAL GENE DELIVERY SYSTEM; VIRUS PARTICLE;

ADENOVIRIDAE; ALGINATES; CARTILAGE; CELLS, CULTURED; CHONDROCYTES; COLLAGEN TYPE II; FLOW CYTOMETRY; GENETIC VECTORS; GLUCURONIC ACID; GREEN FLUORESCENT PROTEINS; HEXURONIC ACIDS; HUMANS; INTEGRINS; RECEPTORS, VITRONECTIN; TRANSDUCTION, GENETIC;

ADENOVIRIDAE;

EID: 33947381825     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00441-006-0371-5     Document Type: Article

References (22)

1. Arai M, Anderson D, Kurdi Y, Annis-Freeman B, Shields K, Collins-Racic LA, Corcoran C, DiBlasio-Smith E, Pittman DD, Dorn AJ, Norris E, LaVallie ER (2004) Effect of adenovirus-mediated overexpression of bovine ADAMTS-4 and human ADAMTS-5 in primary bovine articular chondrocyte pellet culture system. Osteoarthritis Cartilage 12:599-613
2. Bonaventure J, Kadhom N, Cohen-Solal L, Ng KH, Bourguignon J, Lasselin C, Freisinger P (1994) Reexpression of cartilage-specific genes by dedifferentiated human articular chondrocytes cultured in alginate beads. Exp Cell Res 212:97-104
3. Brittberg M, Lindahl A, Nilsson A, Ohlsson C, Isaksson O, Peterson L (1994) Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med 331:889-895
4. Cucchiarini M, Madry H (2005) Gene therapy for cartilage defects. J Gene Med 7:1495-1509
5. Dinser R, Kreppel F, Zaucke F, Blank C, Paulsson M, Kochanek S, Maurer P (2001) Comparison of long-term transgene expression after non-viral and adenoviral gene transfer into primary articular chondrocytes. Histochem Cell Biol 116:69-77
6. Gelse K, Jiang QJ, Aigner T, Ritter T, Wagner K, Poschl E, Mark K von der, Schneider H (2001) Fibroblast-mediated delivery of growth factor complementary DNA into mouse joints induces chondrogenesis but avoids the disadvantages of direct viral gene transfer. Arthritis Rheum 44:1943-1953
7. Gelse K, Mark K von der, Schneider H (2003) Cartilage regeneration by gene therapy. Curr Gene Ther 3:305-317
8. Goessler UR, Bugert P, Bieback K, Sadick H, Baisch A, Hormann K, Riedel F (2006) In vitro analysis of differential expression of collagens, integrins, and growth factors in cultured human chondrocytes. Otolaryngol Head Neck Surg 134:510-515
9. Häuselmann HJ, Fernandes RJ, Mok SS, Schmid TM, Block JA, Aydelotte MB, Kuettner KE, Thonar EJ (1994) Phenotypic stability of bovine articular chondrocytes after long term culture in alginate beads. J Cell Sci 107:17-27
10. Hidaka C, Quitoriano M, Warren RF, Crystal RG (2001) Enhanced matrix synthesis and in vitro formation of cartilage-like tissue by genetically modified chondrocytes expressing BMP-7. J Orthop Res 19:751-758
11. Ikeda T, Kubo T, Nakanishi T, Arai Y, Kobayashi K, Mazda O, Ohashi S, Takahashi K, Imanishi J, Takigawa M, Hirasawa Y (2000) Ex vivo gene delivery using an adenovirus vector in treatment for cartilage defects. J Rheumatol 27:990-996
12. Joronen K, Ala-aho R, Majuri ML, Alenius H, Kahari VM, Vuorio D (2004) Adenovirus mediated intra-articular expression of collagenase-3 (MMP-13) induces inflammatory arthritis. Ann Rheum Dis 63:656-664
13. Kurtis MS, Schmidt TA, Bugbee WD, Loeser RF, Sah RL (2003) Integrin-mediated adhesion of human articular chondrocytes to cartilage. Arthritis Rheum 48:110-118
14. Li T, Tew SR, Russell AM, Gonzalez KR, Hardingham TE, Hawkins RE (2004) Transduction of passaged human articular chondrocytes with adenoviral, retroviral and lentiviral vectors and the effect of enhanced expression of SOX9. Tissue Eng 10:575-584
15. Nemerow GR, Stewart PL (1999) Role of αv integrins in adenovirus cell entry and gene delivery. Microb Mol Biol Rev 63:725-734
16. Nixon AJ, Brower-Toland BD, Brent SJ, Saxer RA, Wilke MJ, Robbins PD, Evans CH (2000) Insulin-like growth factor-I gene therapy applications for cartilage repair. Clin Orthop Relat Res 379:S201-S213
17. Oberholzer A, Oberholzer C, Bahjat KS, Ungaro R, Tannahill CL, Murday M, Bahjat FR, Abouhamze Z, Tsai V, Laface D, Hutchins B, Moldawer LL, Clare-Salzler MJ (2002) Increased survival in sepsis by in vivo adenovirus-induced expression of IL-10 in dendritic cells. J Immunol 168:3412-3418
18. Richardson C, Brennan P, Powell M, Prince S, Chen YH, Spiller OB, Rowe M (2005) Susceptibility of B lymphocytes to adenovirus type 5 infection is dependent upon both coxsackie-adenovirus receptor and alphavbeta5 integrin expression. J Gen Virol 86:1669-1679
19. Schulze-Tanzil G, Souza P de, Villegas Castrejon H, John T, Merker H-J, Scheid A, Shakibaei M (2002) Redifferentiation of dedifferentiated human chondrocytes in high-density cultures. Cell Tissue Res 308:371-379
20. Schulze-Tanzil G, Mobasheri A, Souza P de, John T, Shakibaei M (2004) Loss of chondrogenic potential in dedifferentiated chondrocytes correlates with deficient Shc-Erk interaction and apoptosis. Osteoarthritis Cartilage 12:448-458
21. Verma IM, Somia N (1997) Gene therapy-promises, problems and prospects. Nature 389:239-242
22. Zhang X, Yu C, Shi X, Zhang C, Tang T, Dai K (2006) Direct chitosan-mediated gene delivery to the rabbit knee joints in vitro and in vivo. Biochem Biophys Res Commun 431:202-208