An open-label pilot study to evaluate the safety and efficacy of topically applied pimecrolimus cream for the treatment of steroid-induced rosacea-like eruption

Journal of the European Academy of Dermatology and Venereology

Volumn 21, Issue 4, 2007, Pages 484-490

  Chu, Chia Yu ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Pimecrolimus; Steroid dermatitis; Steroid induced rosacea; Steroid induced rosacea like eruption

Indexed keywords

CORTICOSTEROID; FLUORINATED STEROID; PIMECROLIMUS;

ADOLESCENT; ADULT; AGED; ARTICLE; BURNING SENSATION; CLINICAL ASSESSMENT; CREAM; DISEASE SEVERITY; DRUG EFFICACY; DRUG INDUCED DISEASE; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; ERYTHEMA; FEMALE; HUMAN; MALE; OPEN STUDY; PILOT STUDY; PRIORITY JOURNAL; PRURITUS; ROSACEA; SAMPLE SIZE; SCORING SYSTEM; SKIN MANIFESTATION; STEROID THERAPY; TREATMENT DURATION;

ADMINISTRATION, CUTANEOUS; ADOLESCENT; ADRENAL CORTEX HORMONES; ADULT; AGED; CALCINEURIN; DERMATOLOGIC AGENTS; DRUG ERUPTIONS; ERYTHEMA; FACIAL DERMATOSES; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; PATIENT SATISFACTION; PILOT PROJECTS; ROSACEA; SAFETY; TACROLIMUS; TELANGIECTASIS; TREATMENT OUTCOME;

EID: 33947378220     PISSN: 09269959     EISSN: 14683083     Source Type: Journal    
DOI: 10.1111/j.1468-3083.2006.01991.x     Document Type: Article

References (21)

1. Sneddon I. Adverse effect of topical fluorinated corticosteroids in rosacea. Br Med J 1969; 1: 671-673.
2. Leyden JJ, Kligman AM. Steroid rosacea. Arch Dermatol 1974; 110: 619-622.
3. Wilkin J, Dahl M, Detmar M et al. Standard classification of rosacea: report of the National Rosacea Society expert committee on the classification and staging of rosacea. J Am Acad Dermatol 2002; 46: 584-587.
4. Ljubojeviæ S, Basta-JuzbaSiæ A, Lipozenèiæ J. Steroid dermatitis resembling rosacea: Aetiopathogenesis and treatment. J Eur Acad Dermatol Venereol 2002; 16: 121-126.
5. Wahn U, Bos J, Goodfield M et al. Efficacy and safety of pimecrolimus cream in the long-term management of atopic dermatitis in children. Pediatrics 2002; 110: 1-8.
6. Meurer M, Folster-Holst R, Wozel G et al. Pimecrolimus cream in the long-term management of atopic dermatitis in adults: A six-month study. Dermatology 2002; 205: 271-277.
7. Dale S, Shaw J. Clinical picture: Eosinophilic pustular folliculitis [letter]. Lancet 2000; 356: 1235.
8. Rozycki TW, Rogers RS III, Pittelkow MR et al. Topical tacrolimus in the treatment of symptomatic oral lichen planus: A series of 13 patients. J Am Acad Dermatol 2002; 46: 27-34.
9. Goldman D. Tacrolimus ointment for the treatment of steroid-induced rosacea: A preliminary report. J Am Acad Dermatol 2001; 44: 995-998.
10. Bamford JTM, Elliott BA, Haller IV. Tacrolimus effect on rosacea. J Am Acad Dermatol 2004; 50: 107-108.
11. Chu CY. The use of 1% pimecrolimus cream for the treatment of steroid-induced rosacea. Br J Dermatol 2005; 152: 396-399.
12. Crawford KM, Russ B, Bostrom P. Pimecrolimus for treatment of acne rosacea. Skinmed 2005; 4: 147-150.
13. Wilkin J, Dahl M, Detmar M et al. Standard grading system for rosacea: report of the National Rosacea Society expert committee on the classification and staging of rosacea. J Am Acad Dermatol 2004; 50: 907-912.
14. Thiboutot D, Thieroff-Ekerdt R, Graupe K. Efficacy and safety of azelaic acid (15%) gel as a new treatment for papulopustular rosacea: Results from two vehicle-controlled, randomized phase III studies. J Am Acad Dermatol 2003; 48: 836-845.
15. Wallerath T, Witte K, Schäfer SC et al. Down-regulation of the expression of endothelial NO synthase is likely to contribute to glucocorticoid-mediated hypertension. Proc Natl Acad Sci USA 1999; 96: 13 3 57-13 3 62.
16. Schäfer SC, Wallerath T, Closs EI et al. Dexamethasone suppresses eNOS and CAT-1 and induces oxidative stress in mouse resistance arterioles. Am J Physiol Heart Circ Physiol 2005; 288: H436-H444.
17. Bonnar E, Eustance P, Powell FC. The Demodex mite population in rosacea. J Am Acad Dermatol 1993; 28: 443-448.
18. Bernard L, Cunningham B, Al-Suwaidan S et al. A rosacea-like granulomatous eruption in a patient using tacrolimus ointment. Arch Dermatol 2003; 139: 229-231.
19. Lübbe J, Stucky L, Saurat J-H. Rosaceiform dermatitis with follicular demodex after treatment of facial atopic dermatitis with 1% pimecrolimus cream. Dermatology 2003; 207: 205-207.
20. Antille C, Saurat J-H, Lübbe J. Induction of rosaceiform dermatitis during treatment of facial inflammatory dermatoses with tacrolimus ointment. Arch Dermatol 2004; 140: 457-460.
21. Kempers S, Boguniewicz M, Carter E et al. Comparison of pimecrolimus cream 1% and tacrolimus ointment 0.03% in paediatric patients with atopic eczema. J Eur Acad Dermatol Venereol 2003; 17 (suppl. 3): 183-184.