The effect of testosterone, dihydrotestosterone and oestradiol on the re-initiation of spermatogenesis in the adult photoinhibited Djungarian hamster

Journal of Endocrinology

Volumn 192, Issue 3, 2007, Pages 553-561

  Meachem, Sarah J ^a,b   Schlatt, Stefan ^b,c   Ruwanpura, Saleela M ^a   Stanton, Peter G ^a  

^a HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTANOLONE; ESTRADIOL; FOLLITROPIN; GONADOTROPIN DERIVATIVE; TESTOSTERONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL COUNT; CONTROLLED STUDY; FOLLITROPIN BLOOD LEVEL; GERM CELL; HORMONE ACTION; HORMONE DETERMINATION; HORMONE INHIBITION; MALE; NONHUMAN; PHODOPUS; PHOTOINHIBITION; PRIORITY JOURNAL; SERTOLI CELL; SPERMATID; SPERMATOCYTE; SPERMATOGENESIS; SPERMATOGONIUM;

ANIMALS; CELL COUNT; CRICETINAE; DIHYDROTESTOSTERONE; DRUG IMPLANTS; ESTRADIOL; FOLLICLE STIMULATING HORMONE; GONADAL STEROID HORMONES; MALE; PHODOPUS; PHOTOPERIOD; RADIOIMMUNOASSAY; SERTOLI CELLS; SPERMATOCYTES; SPERMATOGENESIS; SPERMATOGONIA; TESTIS; TESTOSTERONE;

EID: 33947377977     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/JOE-06-0136     Document Type: Article

References (42)

1. Ahmad N, Haltmeyer GC & Eik-Nes KB 1973 Maintenance of spermatogenesis in rats with intratesticular implants containing testosterone or dihydrotestosterone (DHT). Biology of Reproduction 8 411-419.
2. Barlett JM, Weinbauer GF & Nieschlag E 1989 Differential effects of FSH and testosterone on the maintenance of spermatogenesis in the adult hypophysectomized rat. Journal of Endocrinology 121 49-58.
3. Bergmann M 1987 Photoperiod and testicular function in Phodopus surgorus. Advances in Anatomy, Embryology, and Cell Biology 105 1-76.
4. Chandolia RK, Weinbauer GF, Fingscheidt U, Bartlett JMS & Nieschlag E 1991 Effects of flutamide on testicular involution induced by an antagonist of gonadotrophin-releasing hormone and on stimulation of spermatogenesis by follicle-stimulating hormone in rats. Journal of Reproduction and Fertility 93 313-323.
5. Chen H, Chandrashekar V & Zirkin BR 1994 Can spermatogenesis be maintained quantitatively in intact adult rats with exogenously administered dihydrotestosterone? Journal of Andrology 15 132-138.
6. Clermont Y & Harvey SC 1965 Duration of the cycle of the seminiferous epithelium of normal, hypophysectomized and hypophysectomized-hormone treated albino rats. Endocrinology 76 80-89.
7. Deslypere JP, Young M, Wilson JD & McPhaul MJ 1992 Testosterone and 5α-dihydrotestosterone interact differently with the androgen receptor to enhance transcription of the MMTAV-CAT reporter gene. Molecular and Cellular Endocrinology 89 15-22.
8. Ebling FJ, Brooks AN, Cronin AS, Ford H & Kerr JB 2000 Estrogenic induction of spermatogenesis in the hypogonadal mouse. Endocrinology 141 2861-2869.
9. Frungieri MB, Gonzalez-Calvar SI, Bartke A & Calandra RS 1999 Influence of age and photoperiod on steroidogenic function of the testis in the golden hamster. International Journal of Andrology 4 243-252.
10. Grino, PB, Griffin JE & Wilson JD 1990 Testosterone at high concentrations interacts mith the human androgen receptor similarly to dihydrotestosterone. Endocrinology 126 1165-1172.
11. Hess RA, Bunick D, Lee KH, Bahr J, Taylor JA, Korach KS & Lubahn DB 1997 A role for oestrogens in the male reproductive system. Nature 390 509-512.
12. Karri S, Johnson H, Hendry WJ, Williams SC & Khan SA 2004 Neonatal exposure to diethylstilbestrol leads to impaired action of androgens in adult male hamsters. Reproductive Toxicology 19 53-63.
13. Lerchl A 1995 Breeding of Djungarian hamsters (Phodopus sungorus): influence of parity and litter size on weaning success and offspring sex ratio. Laboratory Animals 29 172-176.
14. Lerchl A, Sotiriadou S, Behre HM, Pierce J, Weinbauer GF & Nieschlag E 1993 Restoration of spermatogenesis by follicle-stimulating hormone despite low intratesticular testosterone in photoinhibited hypogonadotropic Djungarian hamsters (Phodopus sungorus). Biology of Reproduction 49 1108-1116.
15. Matthiesson KL, Stanton PG, O'Donnell L, Meachem SJ, Amory JK, Berger R, Bremner WJ & McLachlan RI 2005 Effects of testosterone and levonorgestrel combined with a 5α-reductase inhibitor or gonadotropin-releasing hormone antagonist on spermatogenesis and intratesticular steroid levels in normal men. Journal of Clinical Endocrinology and Metabolism 90 5647-5655.
16. McLachlan RI, Wreford NG, Meachem SJ, de Kretser DM & Robertson DM 1994 Effects of testosterone on spermatogenic cell populations in the adult rat. Biology of Reproduction 51 945-955.
17. McLachlan RI, Wreford NG, de Kretser DM & Robertson DM 1995 The effects of recombinant follicle-stimulating hormone on the restoration of spermatogenesis in the gonadotropin-releasing hormone-immunized adult rat. Endocrinology 136 4035-4043.
18. McLachlan RI, O'Donnell L, Meachem SJ, Stanton PG, de Kretser DM, Pratis K & Robertson DM 2002 Identification of specific sites of hormonal regulation in spermatogenesis in rats, monkeys and man. Recent Progress in Hormone Research 57 149-179.
19. Meachem SJ, McLachlan RI, de Kretser DM, Roberston DM & Wreford NG 1996 Neonatal exposure of rats to recombinant follicle stimulating hormone increases adult Sertoli and spermatogenic cell numbers. Biology of Reproduction 54 36-44.
20. Meachem SJ, Wreford NG, Robertson DM & McLachlan RI 1997 Androgen action on the restoration of spermatogenesis in adult rats: effects of human chorionic gonadotrophin, testosterone and flutamide administration on germ cell number. International Journal of Andrology 20 70-79.
21. Meachem SJ, Wreford NG, Stanton PG, Robertson DM & McLachlan RI 1998 Follicle-stimulating hormone is required for the initial phase of spermatogenic restoration in adult rats following gonadotrophin suppression. Journal of Andrology 19 725-735.
22. Meachem SJ, Stanton PG & Schlatt S 2005 Follicle stimulating hormone (FSH) regulates both Sertoli cell and spermatogonial populations in the adult photo-inihibited Djungarian hamster testis. Biology of Reproduction 72 1187-1193.
23. Milette JJ, Schwartz NB & Turek FW 1988 The importance of follicle-stimulating hormone in the initiation of testicular growth in photo-stimulated Djungarian hamsters. Endocrinology 122 1060-1066.
24. Niklowitz P, Khan S, Bergmann M, Hoffmann K & Nieschlag E 1989 Differential effects of follicle-stimulating hormone and luteinizing hormone on Leydig cell function and restoration of spermatogenesis in hypophy-sectomized and photoinhibited Djungarian hamsters (Phodopus sungorus). Biology of Reproduction 41 871-880.
25. Niklowitz P, Lerchl A & Nieschlag E 1997 In vitro fertilizing capacity of sperm from FSH-treated photoinhibited Djungarian hamsters (Phodopus sungorus). Journal of Endocrinology 154 475-481.
26. Nonclercq D, Reverse D, Toubeau G, Beckers JF, Sulon J, Laurent G, Zanen J & Henson-Stiention JA 1996 In situ demonstration of germinal cell apoptosis during diethylstilbestrol-induced testis regression in adult male Syrian hamsters. Biology of Reproduction 55 1368-1376.
27. O'Donnell L, Stanton PG, Wreford NG, Robertson DM & McLachlan RI 1996 Inhibition of 5α-reductase activity impairs the testosterone-dependent restoration of spermiogenesis in adult rats. Endocrinology 137 2703-2710.
28. O'Donnell L, Pratis K, Stanton PG, Robertson DM & McLachlan RI 1999 Testosterone-dependent restoration of spermatogenesis in adult rats is impaired by a 5alpha-reductase inhibitor. Journal of Andrology 20 109-117.
29. O'Donnell L, Robertson KM, Jones ME & Simpson ER 2001 Estrogen and spermatogenesis. Endocrine Reviews 22 289-318.
30. Oliveira CA, Carnes K, Franca LR & Hess RA 2001 Infertility and testicular atrophy in the antiestrogen-treated adult male rat. Biology of Reproduction 65 913-920.
31. Oliveira CA, Zhou Q, Carnes K, Nie R, Kuehl DE, Jackson GL, Franca LR, Nakai M & Hess RA 2002 ER function in the adult male rat: short- and long-term effects of the antiestrogen ICI 182,780 on the testis and efferent ductules, without changes in testosterone. Endocrinology 143 2399-2409.
32. Pak TR, Lynch GR & Tsai PS 2001 Testosterone and estrogen act via different pathways to inhibit puberty in the male Siberian hamster (Phodopus sungorus). Endocrinology 142 3309-3316.
33. Pak TR, Lynch GR & Tsai PS 2002 Estrogen accelerates gonadal recrudescence in photo-regressed rude siberian hamsters. Endocrinology 143 4131-4134.
34. Robaire B, Ewing LL, Irby DC & Desjardings C 1979 Interactions of testosterone and estradiol- 17β on the reproductive tract of the male rat. Biology of Reproduction 21 455-463.
35. Robertson KM, O'Donnell L, Jones ME, Meachem SJ, Boon WC, Fisher CR, Graves KH, McLachlan RI & Simpson ER 1999 Impairment of spermatogenesis in mice lacking a functional aromatase (cyp 19) gene. PNAS 96 7986-7991.
36. Russell LD, Ettlin RA, Sinha Hikim AP & Clegg ED 1990 Histological and Histopathological Evaluation of the Testis I, pp. 62-118. Clearwater, Florida: Cache River Press.
37. Schlatt S, De Geyter M, Kliesch S, Nieschlag E, Bergmann M, Nieschlag E & Bergmann M 1995 Spontaneous recrudescence of spermatogenesis in the photoinhibited male Djungarian hamster, Phodopus sungorus. Biology of Reproduction 53 1169-1177.
38. Tarulli GA, Stanton PG, Lerchl A & Meachem SJ 2006 Adult Sertoli cells are not terminally differentiated in die Djungarian hamster: effect of FSH on proliferation and junction protein organization. Biology of Reproduction 74 798-806.
39. van Haaster LH & De Rooij DG 1993 Cycle of the seminiferous epithelium in the Djungarian hamster (Phodopus surgorus). Biology of Reproduction 48 515-521.
40. Wilson J 1975 Metabolism of Testicular Androgens. In: Handbook of Physiology, Section 7, Vol V, pp 491-508. Eds RO Greep & EB Astwood, Waverly Press, Inc., Maryland.
41. Wreford NG 1995 Theory and practice of stereological techniques applied to the estimation of cell number and nuclear volume in the testis. Microscopy Research and Technique 32 423-436.
42. Zhou Z, Lane MV, Kemppainen JA, French FS & Wilson EM 1995 Specificity of ligand-dependent androgen receptor stabilization: receptor domain interactions influence ligand dissociation and receptor stability. Molecular Endocrinology 9 208-218.