Studies of associations between the Arg389Gly polymorphism of the β1-adrenergic receptor gene (ADRB1) and hypertension and obesity in 7677 Danish white subjects

Diabetic Medicine

Volumn 24, Issue 4, 2007, Pages 392-397

  Gjesing, A P ^a   Andersen, G ^a   Albrechtsen, A ^a   Glumer C ^a,b   Borch Johnsen, K ^a,b,c   Jorgensen T ^b   Hansen, T ^a   Pedersen, O ^a,c  

^a STENO DIABETES CENTER   (Denmark)

^b GLOSTRUP UNIVERSITY HOSPITAL   (Denmark)

^c AARHUS UNIVERSITY   (Denmark)

Author keywords

Adrenergic receptor; Epidemiology; Genetics; Hypertension; Obesity

Indexed keywords

ARGININE; BETA 1 ADRENERGIC RECEPTOR; GLYCINE;

ADULT; ARTERIAL PRESSURE; ARTICLE; BODY MASS; CASE CONTROL STUDY; CONTROLLED STUDY; DENMARK; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; OBESITY; POPULATION RESEARCH; QUANTITATIVE TRAIT; SYSTOLIC BLOOD PRESSURE;

ADULT; AGED; ALLELES; DENMARK; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; EPIDEMIOLOGIC STUDIES; FEMALE; GENOTYPE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; OBESITY; POLYMORPHISM, GENETIC; RECEPTORS, ADRENERGIC, BETA-1;

EID: 33947366956     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/j.1464-5491.2006.02031.x     Document Type: Article

References (32)

1. Collins S, Cao W, Robidoux J. Learning new tricks from old dogs: β-adrenergic receptors teach new lessons on firing up adipose tissue metabolism. Mol Endocrinol 2004; 18: 2123-2131.
2. Lafontan M, Berlan M. Fat cell adrenergic receptors and the control of white and brown fat cell function. J Lipid Res 1993; 34: 1057-1091.
3. Brodde O-E, Michel MC. Adrenergic and muscarinic receptors in the human heart. Pharmacol Rev 1999; 51: 651-690.
4. 1-adrenoceptor: identification and rapid screening assay. Lancet 1999; 353: 897.
5. 1-Adrenoceptor gene variations: a role in idiopathic dilated cardiomyopathy? J Mol Med 2000; 78: 87-93.
6. 1-adrenergic receptor. J Biol Chem 1999; 274: 12670 -12674.
7. 1-adrenergic receptor exhibits constitutive activity and increased desensitization and downregulation. J Biol Chem 2002; 277: 30429-30435.
8. Terra SG, McGorray SP, Wallace MR, Picoult-Newberg L, Pepine CJ, Johnson JA. Linkage disequilibrium of common β1 adrenergic receptor polymorphisms. Clin Pharmacol Ther 2002; 71: P70.
9. 1-adrenergic receptor gene and hypertension. Circulation 2001; 104: 187-190.
10. 1-adrenergic receptor predict exercise capacity in heart failure. Am Heart J 2002; 144: 840-846.
11. Ranade K, Jorgenson E, Sheu WH-H, Pei D, Hsiung CA, Chiang F-t et al. A polymorphism in the β1 adrenergic receptor is associated with resting heart rate. Am J Hum Genet 2002; 70: 935-942.
12. 1-adrenoceptor polymorphism in humans. Pharmacogenetics 2001; 11: 199-205.
13. 1-adrenoceptor polymorphism varies in frequency among different ethnic groups but does not alter response in vivo. Pharmacogenetics 2001; 11: 191-197.
14. 1-adrenergic receptor is associated with the cardiovascular response to metoprolol. Clin Pharmacol Ther 2003; 74: 372-379.
15. 1-adrenoceptor polymorphism does not affect cardiac effects of exercise after parasympathetic inhibition by atropine. Pharmacogenet Genomics 2006; 16: 9-13.
16. 1-Adrenergic receptor polymorphisms and anti-hypertensive response to metoprolol. Clin Pharmacol Ther 2003; 74: 44-52.
17. 1-adrenergic receptor polymorphism (Arg389Gly) affects blood pressure response to β-blockade. Clin Pharmacol Ther 2003; 73: 366-371.
18. 1-adrenoceptor gene polymorphism determines contractile response to catecholeamines. Pharmacogenetics 2004; 14: 711-716.
19. 1-adrenergic receptor blockade in patients with essential hypertension. Clin Cardiol 2004; 27: 347-350.
20. 2-adrenergic receptors. Eur J Endocrinol 2000; 143: 439-445.
21. 1-adrenergic receptor protein concentration in adipose tissue correlates with diet-induced weight loss. Clin Sci 2005; 108: 323-329.
22. 1-adrenergic receptor gene polymorphism and human fat cell lipolysis. Int J Obes 2001; 25: 1599-1603.
23. 3-adrenergic receptor genes are not associated with morbid obesity in children and adolescents. Diabetes Obes Metab 2004; 6: 452-455.
24. Terra SG, McGorray SP, Wu R, McNamara DM, Cavallari LH, Walker JR et al. Association between β-adrenergic receptor polymorphisms and their G-protein-coupled receptors with body mass index and obesity in women: a report from the NHLBI-sponsored WISE study. Int J Obes 2005; 29: 746-754.
25. Linné Y, Dahlman I, Hoffstedt J. β1-Adrenoceptor gene polymorphism predicts long-term changes in body weight. Int J Obes 2005; 29: 458-462.
26. 1-adrenoceptor gene (Gly389Arg ADRB1) in Caucasian women. Int J Obes 2002; 26: 633-639.
27. Jørgensen T, Borch-Johnsen K, Thomsen TF, Ibsen H, Glümer C, Pisinger C. A randomized non-pharmacological intervention study for prevention of ischaemic heart disease: baseline results Inter99 (1). Eur J Cardiovasc Prev Rehabil 2003; 10: 377-386.
28. Drivsholm T, Ibsen H, Schroll M, Davidsen M, Borch-Johnsen K. Increasing prevalence of diabetes mellitus and impaired glucose tolerance among 60-year-old Danes. Diabet Med 2001; 18: 126-132.
29. Alberti KGMM, Zimmett PZ for a WHO consultation. Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications. Part 1: Diagnosis and Classification of Diabetes Mellitus. Geneva, Switzerland: World Health Organisation, 1999.
30. Buetow KH, Edmonson M, MacDonald R, Clifford R, Yip P, Kelley J et al. High-throughput development and characterization of a genome-wide collection of gene-based single nucleotide polymorphism markers by chip-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Proc Natl Acad Sci USA 2001; 98: 581-584.
31. Ellsworth DL, Coady SA, Chen W, Srinivasan SR, Boerwinkle E, Berenson GS. Interactive effects between polymorphisms in the β-adrenergic receptors and longitudinal changes in obesity. Obes Res 2005; 13: 519-526.
32. 3-adrenoceptor deficiency in brown adipocyte norepinephrine-stimulated glucose uptake. Endocrinology 2005; 146: 2271-2284.