Assembly defects of desmin disease mutants carrying deletions in the α-helical rod domain are rescued by wild type protein

Journal of Structural Biology

Volumn 158, Issue 1, 2007, Pages 107-115

  Bär, Harald ^a   Mücke, Norbert ^b   Katus, Hugo A ^a   Aebi, Ueli ^c   Herrmann, Harald ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Assembly; Deletion mutation; Desmin; Intermediate filament disease; Myofibrillar myopathy

Indexed keywords

DESMIN;

ARTICLE; BONE DISEASE; GENE DELETION; GENE MUTATION; HUMAN; HUMAN CELL; MOLECULAR GENETICS; MUSCLE CELL; MYOPATHY; PRIORITY JOURNAL; WILD TYPE;

DESMIN; DIMERIZATION; HUMANS; MUSCULAR DISEASES; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE DELETION; ULTRACENTRIFUGATION; VISCOSITY;

EID: 33947307160     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2006.10.029     Document Type: Article

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