Calcific uremic arteriolopathy: Advances in pathogenesis and treatment

Seminars in Dialysis

Volumn 20, Issue 2, 2007, Pages 150-157

  Rogers, Natasha M ^a   Teubner, David J O ^b   Coates, P Toby H ^a,c  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b ROYAL ADELAIDE HOSPITAL   (Australia)

^c QUEEN ELIZABETH HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE;

ARTERIOLE; ARTICLE; CALCINOSIS; CHRONIC KIDNEY FAILURE; HUMAN; METABOLISM; PARATHYROIDECTOMY; PATHOLOGY; UREMIA;

ARTERIOLES; CALCIPHYLAXIS; DIPHOSPHONATES; HUMANS; KIDNEY FAILURE, CHRONIC; PARATHYROIDECTOMY; UREMIA;

EID: 33947301953     PISSN: 08940959     EISSN: 1525139X     Source Type: Journal    
DOI: 10.1111/j.1525-139X.2007.00263.x     Document Type: Article

References (55)

1. Coates T, Kirkland GS, Dymock RB, Murphy BF, Brealey JK, Mathew TH, Disney APS: Cutaneous necrosis from calcific uraemic arteriolopathy. Am J Kidney Dis 32:384-391, 1998
2. Pollock B, Cunliffe W, Merchant W: Calciphylaxis in the absence of renal failure. Clin Exp Dermatol 25:389, 2000
3. Goyal S, Huhn K, Provost T: Calciphylaxis in a patient without renal failure or elevated parathyroid hormone: the possible aetiological role of chemotherapy. Br J Dermatol 143:1087, 2000
4. Angelis M, Wong L, Myers S, Wong L: Calciphylaxis in patients on haemodialysis: a prevalence study. Surgery 122:1083, 1997
5. McDonald SP, Excell L: ANZDATA Registry Report. Adelaide, 2005
6. Mazhar AR, Johnson RJ, Gillen D, Stivelman JC, Ryan MJ, Davis CL, Stehman-Breen CO: Risk factors and mortality associated with calciphylaxis in end-stage renal disease. Kidney Int 60:324-332, 2001
7. Wilmer WA, Magro CM: Calciphylaxis: emerging concepts in prevention, diagnosis, and treatment. Semin Dial 15:172-186, 2002
8. Bleyer AJ, Choi M, Igwemezie B, de la Torre E, White WL: A case control study of proximal calciphylaxis. Am J Kidney Dis 32:376-383, 1998
9. Winkelmann R, Keating F: Cutaneous vascular calcification gangrene and hyperparathyroidism. Br J Dermatol 83:263-268, 1970
10. Khafif RA, Delima C, Silverberg A, Frankel R, Groopman J: Acute hyperparathyroidism with systemic calcinosis. Report of a case.. Arch Intern Med 149:681-684, 1989
11. Mirza I, Chaubay D, Gunderia H, Winston S, El-Fanek H: An unusual presentation of calciphylaxis due to primary hyperparathyroidism. Arch Pathol Lab Med 125:1351-1353, 2001
12. Giachelli CM: Vascular calcification mechanisms. J Am Soc Nephrol 15:2959-2964, 2004
13. Giachelli CM, Jono S, Shioi A, Nishizawa Y, Mori K, Morii H: Vascular calcification and inorganic phosphate. Am J Kidney Dis 38:S34-S37, 2001
14. Nishizawa Y, Jono S, Ishimura E, Shioi A: Hyperphosphatemia and vascular calcification in end-stage renal disease. J Ren Nutr 15:178-182, 2005
15. Ahmed S, O'Neill KD, Hood AF, Evan AP. Moe SM: Calciphylaxis is associated with hyperphosphatemia and increased osteopontin expression by vascular smooth muscle cells. Am J Kidney Dis 37:1267-1276, 2001
16. Griethe W, Schmitt R, Jurgensen JS, Bachmann S, Eckardt KU, Schindler R: Bone morphogenic protein-4 expression in vascular lesions of calciphylaxis. J Nephrol 16:728-732, 2003
17. Schaffer C, Heiss A, Schwarz A, Westenfeld R, Ketteler M, Floege J, Muller-Esterl W. Schinke T, Jahnen-Dechent W: The serum protein a2-Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification. J Clin Invest 112:357-366, 2003
18. Perez-Mijares R, Guzman-Zamudio J, Payan-Lopez J, Rodriguez-Fernandez A, Gomez-Fernandez P, Almaraz-Jimenez M: Calciphylaxis in a haemodialysis patient: Functional protein S deficiency? Nephrol Dial Transplant 11:1856-1859, 1996
19. Kane W, Petty PM, Sterioff S, McCarthy J, Crotly T: The uraemic gangrene syndrome: improved healing in spontaneously forming wounds following subtotal parathroidectomy. Past Reconstr Surg 98:671, 1996
20. Duh Q, Lim R, Clark O: Calciphylaxis in secondary hyperparathyroidism: diagnosis and parathyroidectomy. Arch Surg 126:1213, 1991
21. Kang A, Mc Carthy J, Rowland C, Farley D, vanHeerden J: Is calciphylaxis best treated surgically or medically? Surgery 128:967, 2000
22. Girotto JA, Harmon JW, Ratner LE, Nichol TL, Wong L, Chen H: Parathyroidectomy promotes wound healing and prolongs survival in patients with calciphylaxis from secondary hyperparathyroidism. Surgery 130:645-651, 2001
23. Hafner J, Keusch G, Wahl C, Sauter B, Hurlimann A, von Weizsacker F, Krayenbuhl M, Biedermann K, Brunner U, Helfenstein U: Uremic small-artery disease with medial calcification and intimal hyperplasia (so-called calciphylaxis): a complication of chronic renal failure and benefit from parathyroidectomy. J Am Acad Dermatol 33:954-962, 1995
24. Velasco N, MacGregor M, Innes A, Mackay I: Successful treatment of calciphylaxis with cinacelcet- an alternative to parathyroidectomy? Nephrol Dial Transplant 21:1999-2004, 2006
25. Monney P, Nguyen Q-V, Perroud H, Descombes E: Rapid improvement of calciphylaxis after intravenous pamidronale therapy in a patient with chronic renal failure. Nephrol Dial Transplant 19:2130-2132, 2004
26. Shiraishi N, Kitamura K, Miyoshi T, Adachi M, Kohda Y, Nonoguchi H, Misumi S, Maekawa Y, Murayama T, Tomita M, Tomita K: Successful treatment of a patient with severe calcific uremic arteriolopathy (calciphylaxis) by etidronate sodium. Am J Kidney Dis 48:151-154, 2006
27. Cecchini MG, Felix R, Fleisch H, Cooper PH: Effects of bisphosphonates on proliferation and viability of mouse bone marrow derived macrophages. J Bone Miner Res 2:135-142, 1987
28. Pennanen N, Lapinjoki S, Urtti A, Monkkonen J: Effect of liposomal and free bisphosphonates on IL-1 beta, IL-6 and TNF alpha secretion from RAW 264 cells in vitro. Pharm Res 12:916-922, 1995
29. Miller S, Vernon-Roberts E, McClure J: Cutaneous calciphylactic reactions in the mouse and the rat and the effects of diphosphonates on the reaction in the rat. J Pathol 142:7-13, 1984
30. Viereck V, Emons G, Lauck Vm, Frosch KH, Blascke S, Grundker C, Hofbrauer LC: Bisphosphonate pamidronale and zoledronic acid simulate osteoprotegerin production by human osteoblasts. Biochem Biophys Res Common. 291:680-686, 2002
31. Sewell LD, Weenig RH, Davis MDP, McEvoy MT, Pitlelkow MR: Low dose tissue plasminogen activator for calciphylaxis. Arch Dermatol 140:1043-1048, 2004
32. Brucculeri M, Cheigh J, Bauer G, Serur D: Long-term intravenous sodium thiosulfate in the treatment of a patient with caleiphylaxis. Semin Dial 18:431-434, 2005
33. Cicone JS, Petronis JB, Embert CD, Spector DA: Successful treatment of calciphylaxis with intravenous sodium thiosulfale. Am J Kidney Dis 43:1104-1108, 2004
34. Guerra G, Shah R, Ross E: Rapid resolution of caleiphylaxis with intravenous sodium thiosulfate and continuous venovenous haemofiltration using low calcium replacement fluid: case report. Nephrol Dial Transplant 20:1260-1262, 2005
35. Kyriakopoulos G, Kontogianni K: Sodium thiosulfate treatment of tumoral calcinosis in patients with end-stage renal failure. Ren Fail 12:213, 1990
36. Yatzidis H: Successful sodium thiosulphatc treatment for recurrent calcium urolilhiasis. Clin Nephrol 23:63-67, 1985
37. Hayden M, Tyagi S, Kolb L, Sowers J, Khanna R: Vascular ossification-calcification in metabolic syndrome, type 2 diabetes mellilus, chronic kidney disease, and calciphylaxis-calcific uremic arteriolopathy: the emerging role of sodium thiosulfate. Cardiovasc Diahetol 4:4, 2005
38. Riegert-Johnson D, Kaur J, Pfeifer E: Calciphylaxis associated with cholangiocarcinoma treated with low-molecular-weight heparin and vitamin K. Mayo Clin Proc. 76:749-752, 2001
39. Campanelli A, Kaya G, Masouye I, Borradori L: Calcifying panniculilis following subcutaneous injections of nadroparin-calcium in a patient with osteomalacia. Br J Dermatol 153:657-660, 2005
40. van Haren F, Ruiler D, Hilbrands L: Nadroparin-induced Calcinosis cutis in renal transplant recipients. Nephron 87:279-282, 2001
41. Goldsmith D: Calciphylaxis, thrombotic diathesis and defects in coagulation regulation. Nephrol Dial Transplant 12:1082-1083. 1997
42. Ruggian J, Maesaka J, Fishbane S: Proximal calciphylaxis in four insulin-requiring diabetic hemodialysis patients. Am J Kidney Dis 28:409-414, 1996
43. Reenstra WR, Dittmer C, Buras JA: Human dermal fibroblasts vary the expression of growth factor receptors in response to in vitro oxygen levels. Undersea Hyperb Med 26(Suppl.):71, 1999
44. Reenstra WR, Buras JA, Svoboda KS: Hyperbaric oxygen increases human dermal fibroblast proliferation, growth factor receptor number and in vitro wound closure. Undersea Hyperb Med 25(Suppl.):53, 1998
45. Knighton DR, Silver IA, Hunt TK: Regulation of wound healing angiogenesis - effect of oxygen gradients and inspired oxygen concentration. Surgery 90:262-270, 1981
46. Marx RE. Ehler WJ, Tayapongsak P, Pierce LW: Relationship of oxygen dose to angiogenesis induction in irradiated tissue. Am J Surg 160:519-524, 1990
47. Banky JM, Dowling JP, Miles C: Idiopathic calciphylaxis. Aust J Dermatol 43:190-193, 2002
48. Basile C, Montanaro A, Masi M: Hyperbaric oxygen therapy for calcific uremic arteriolopathy: a case series. J Nephrol 15:676-685, 2002
49. Benedetto B, Emhoff T: The use of hyperbaric oxygen for the management of calciphylaxis. Curr Surg 57:507, 2000
50. Vassa N, Twardowski Z, Campbell J: Hyperbaric oxygen therapy in calciphylaxis-induced skin necrosis in a peritoneal dialysis patient. Am J Kidney Dis 23:878, 1994
51. Don B, Chin A: A strategy for the treatment of calcific uraemic arteriolopathy (calciphylaxis) employing a combination of therapies. Clin Nephrol 59:463, 2003
52. Dean S, Werman H: Calciphylaxis: a favourable outcome with hyperbaric oxygen. Vasc Med 3:115, 1998
53. Dwyer KM, Francis DMA, Hill PA, Murphy BF: Calciflc uraemic arteriolopathy: local treatment and hyperbaric oxygen therapy. Nephrol Dial Transplant 17:1148-1149, 2002
54. Oikawa S, Osajima A, Tamura M, Murata K, Yasuda H, Nai H, Kabashima N, Matsushima Y, Nakamoto M, Nakashima Y: Development of proximal calciphylaxis with penile involvement after parathyroidectomy in a patient on hemodialysis. Intern Med 43: 63-68, 2004
55. Podymow T, Wherrett C, Burns K: Hyperbaric oxygen in the treatment of calciphylaxis: a case series. Nephrol Dial Transplant 16:2176-2108, 2001