Mechanisms of chronic skin ulceration linking lactate, transforming growth factor-β, vascular endothelial growth factor, collagen remodeling, collagen stability, and defective angiogenesis

Journal of Investigative Dermatology

Volumn 127, Issue 4, 2007, Pages 958-968

  Dalton, Stephen John ^a,b   Whiting, Christine Vivienne ^b   Bailey, Jennifer Ruth ^b   Mitchell, David Charles ^a   Tarlton, John Francis ^b  

^a SOUTHMEAD HOSPITAL   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; GELATINASE A; INTERSTITIAL COLLAGENASE; LACTIC ACID; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

ADULT; AGED; ANGIOGENESIS; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME DEGRADATION; FEMALE; HUMAN; HUMAN TISSUE; INFLAMMATORY CELL; ISCHEMIA; MALE; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN METABOLISM; PROTEIN STABILITY; SKIN ULCER; TISSUE REPAIR; UPREGULATION;

AGED; AGED, 80 AND OVER; CHRONIC DISEASE; COLLAGEN; DISEASE SUSCEPTIBILITY; DRUG STABILITY; FEMALE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; ISCHEMIA; LACTATES; MALE; MIDDLE AGED; NEOVASCULARIZATION, PHYSIOLOGIC; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; SIGNAL TRANSDUCTION; SKIN; SKIN ULCER; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33947290139     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5700651     Document Type: Article

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