Antinociceptive and anti-inflammatory activities and acute toxicity of Achillea nobilis subsp. neilreichii extract in mice and rats

Pharmaceutical Biology

Volumn 45, Issue 2, 2007, Pages 162-168

  Karabay Yavasoglu, N U ^a   Karamenderes, C ^a   Baykan, S ^a   Apaydin, S ^a  

^a EGE UNIVERSITY   (Turkey)

Author keywords

Achillea nobilis; Acute toxicity; Anti inflammatory; Antinociceptive; Asteraceae; Subsp. neilreichii

Indexed keywords

ACHILLEIC NOBILIS NEILREICHII EXTRACT; FORMALDEHYDE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ACHILLEA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; HOT PLATE TEST; LATENT PERIOD; LC 50; MALE; MOUSE; NONHUMAN; PAW EDEMA; PERFORMANCE; RAT; SENSORIMOTOR FUNCTION; TAIL FLICK TEST;

ACHILLEA NOBILIS; ASTERACEAE; MUS; RATTUS;

EID: 33947278384     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.1080/13880200601113149     Document Type: Article

References (38)

1. Abbasoǧlu U, Küsmenoǧlu Ş (1994): Antibacterial and antifungal studies on Achillea L. species. J Fac Pharm Gazi 11: 177-181.
2. Baytop T (1999): Türkiye'de Bitkiler ile Tedavi (Geçmişte ve Bugün), 2nd ed. Istanbul, Nobel Tip Kitabevleri, pp. 332.
3. Chi YS, Jong HG, Son KH, Wook H, Chang HW, Kang SS, Kim HP (2001): Effects of naturally occurring prenylated flavonoids on enzymes metabolizing arachidonic acid: Cyclooxygenases and lipoxygenases. Biochem Pharmacol 62: 1185-1119.
4. Di Carlo G, Mascolo N, Izzo AA, Capasso F (1999): Flavonoids: Old and new aspects of a class of natural therapeutic drugs. Life Sci 65: 337-353.
5. Dimartino MJ, Griswold DE, Berkowitz BA, Poste G, Lewis AJ (1987): Pharmacologic characterization of the anti-inflammatory properties of a new dualinhibor of lipoxygenase and cyclooxygenase. Agents Actions 20: 113-123.
6. Elisabetsky E, Amador TA, Albuquerque RR, Nunes DS, Carvalho AC (1995): Analgesic activity of Psychotria colorata Muell. alkaloids. J Ethnopharmacol 48: 77-83.
7. Fantone JC, Ward PA (1982): Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions. Am Pathol 107: 395-418.
8. Gear RW, Gordon NC, Miaskowski C, Paul SM, Heller PH, Levine JD (2003): Dose ratio is important in maximizing naloxone enhancement of nalbuphine analgesia in humans. Neurosci Lett 351: 5-8.
9. Hall IH, Lee KH, Starnes CO, Waddell TG (1979): Anti-inflammatory activity of sesquiterpene lactones and related compounds. J Pharm Sci 67: 537-541.
10. Hall IH, Starnes CO, Lee KH, Sumida YR, Wu RY, Waddell T, Cochran JW, Gerhart V (1980): Mode of action of sesquiterpene lactones as anti-inflammatory agents. J Pharm Sci 69: 537-543.
11. Handy RLC, Wallace P, Gaffen ZA, Whitehead KJ, Moore PK (1995): The antinociceptive effect of 1-(2-trifluoromethylphenyl) imidazole (TRIM), a potent inhibitor of neuronal nitric oxide synthase in vitro, in the mouse. Br J Pharmacol 116: 2349-2350.
12. Hehner SP, Heinrich M, Bork PM, Vogt M, Ratter F, Lehmann V, Schulze-Osthoff K, Dröge W, Shmitz ML (1998): Sesquiterpene lactones specifically inhibit activation of NF-κB by preventing the degration of I-κBα and I-κBβ. J Biol Chem 273: 1288-1297.
13. Hunskaar S, Hole K (1987): The formalin test in mice: Dissociation between inflammatory and non-inflammatory pain. Pain 30: 103-114.
14. Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CWW, Fong HHS, Farnsworth NR, Kinghorn AD, Mehta RG, Pezzuto JM (1997): Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 275: 218-220.
15. Karamenderes C, Apaydin Ş (2003): Antispasmodic effect of Achillea nobilis L. subsp. sipylea (O. Schwarz) Bässler on the rat isolated duodenum. J Ethnopharmacol 84: 175-179.
16. Kastner U, Glasl S, Jurenitsch J (1995a): Achilea millefolium-ein Gallentherapeuticum? Z Phytoterapie 16: 34-39.
17. Kastner U, Breuer J, Glasl S, Baumann A, Robien W, Jurenitsch J, Kubelka W (1995b): Guanolide endoperoxide and monoterpene-hydroperoxides from Achillea nobilis. Planta Med 61: 83-85.
18. Kastner U, Jurenitsch J, Glasl S, Follrich B, Gavanelli A, Schroder H, Schubertz silavace M, Schmidt W, Haslinger E, Kubelka W (1996): Longipinen and achillifolin derivatives from Achillea millefollum type "DISA." Pharmazie 51: 503-505.
19. Konyalioǧlu S, Karamenderes C (2004): Screening of total flavonoid, phenol contents and antioxidant capacities of Achillea L. species growing in Turkey. Acta Pharm Turcica 46: 163-170.
20. 2-induced oxidative damage in human erythrocytes and leucocytes. J Ethnopharmacol 102: 221-225.
21. Krenn L, Miron A, Pemp E, Petr U, Kopp B (2003): Flavonoids from Achillea nobilis L. Biosciences 58: 11-16.
22. Marchart E, Hattenberger A, Krenn L, Kopp B (2003): Analysis of flavonoids in Achillea nobilis L. by capillary electrophoresis. Sci Pharm 71: 133-145.
23. Miles EA, Zoubouli P, Calder PC (2005): Differential anti-inflammatory effects of phenolic compounds from extra virgin olive oil identified in human whole blood cultures. Nutrition 21: 389-394.
24. Morteza-Semnani K, Saeedi M, Hamidian M, Vafamehr H, Dehpour AR (2002): Anti-inflammatory, analgesic activity and acute toxicity of Glaucium grandiflorum extract. J Ethnopharmacol 80: 181-186.
25. Palic R, Stojanovic G, Naskovic T, Ranelovic N (2003): Composition and antibacterial activity of Achillea crithmifolia and Achillea nobilis essential oils. JEOR 15: 434-437.
26. Pieretti S, Dal Piaz V, Matucci R, Giovannoni MP, Galli A (1999): Antinociceptive activity of a 3(2H)-pyridazinone derivative in mice. Life Sci 65: 1381-1394.
27. Rao TS, Basu N, Siddiqui HH (1982): Anti-inflammatory activity of curcumin analogues. Indian J Med Res 75: 574-578.
28. Rojas-Corrales MO, Casas J, Moreno-Brea MR, Gibert-Rahola J, Mico JA (2003): Antinociceptive effects of tricyclic antidepressants and their noradrenergic metabolites. Eur Neuropsychopharm 13: 355-363.
29. Rosland JH, Tjolsen A, Maehle B, Hole DK (1990): The formalin test in mice. Effect of formalin concentration. Pain 42: 235-242.
30. Rupniak NM, Boyce S, Williams AR, Cook G, Longmore J, Seabrook GR, Caeser M, Iversen SD, Hill RG (1993): Antinociceptive activity of NK1 receptor antagonists: Non-specific effects of racemic RP67580. Br J Pharmacol 110: 1607-1613.
31. Schapoval E, De Vargas M, Chaves C, Bridi R, Zuanazzi J, Henriques A (1998): Anti-inflammatory and antinociceptive activities of extracts and isolated compouds from Stachytarpheta cayennensis. J Ethnopharmacol 60: 53-59.
32. Segura L, Vila R, Gupta MP, Esposito-Avella M, Adzet T, Canigueral S (1998): Anti-inflammatory activity of Anthurium cerrocampanense Croat in rats and mice. J Ethnopharmacol 61: 243-248.
33. Shibata M, Ohkubo T, Takahashi H, Inoki R (1989): Modified formalin test: Characteristic biphasic pain response. Pain 38: 347-352.
34. Tjolsen A, Berge OG, Hunskaar S, Rosland JH, Hole K (1992): The formalin test: An evaluation of the method. Pain 51: 5-17.
35. Turdybekov KM, Turmukhambetov AZ, Adekenov SM, Struchkov YT (1994): Anolide, a new guaianolide from Achillea nobilis. Khimiya Prirodnykh Soedinenii 4: 500-504.
36. Turmukhambetoy AZ, Buketova GK, Gafurov NM, Adekenov SM (1999): Chrysartemin A and canin from Achillea nobilis. Chem Nat Comp 35: 102.
37. Valant-Vetschara KM, Karin M (1986): Flavonoid patterns of Achillea. Part 5. Flavonoid glycoside accumulation trends of Achillea nobilis L. and related species. Biochem Syst Ecol 15: 45-52.
38. Zimmermann M (1983): Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16: 109-110.