Construction and functional analysis of a lentiviral expression vector containing a Scavenger Receptor (SR-PSOX) that binds uniquely phosphatidylserine and oxidized lipoprotein

Acta Biochimica et Biophysica Sinica

Volumn 39, Issue 3, 2007, Pages 208-216

  Quan, Zhihua ^a   Yang, Hulling ^a   Yang, Yongzong ^a   Yan, Bin ^a   Cao, Renxian ^a   Wen, Gebo ^a   Liu, Changhui ^a   Xu, Yangyan ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

Atherosclerosis; Lentiviral expression vector; SR PSOX; TNF

Indexed keywords

ALPHA CHEMOKINE; CXCL16 PROTEIN, HUMAN; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHATIDYLSERINE; PRIMER DNA; SCAVENGER RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; ATHEROSCLEROSIS; BIOSYNTHESIS; CELL LINE; FOAM CELL; GENE VECTOR; GENETICS; HUMAN; LENTIVIRINAE; METABOLISM; MOLECULAR GENETICS; NASOPHARYNX TUMOR; NUCLEOTIDE SEQUENCE; PATHOLOGY; PROTEIN BINDING;

ATHEROSCLEROSIS; BASE SEQUENCE; CELL LINE; CHEMOKINES, CXC; DNA PRIMERS; FOAM CELLS; GENETIC VECTORS; HUMANS; LENTIVIRUS; LIPOPROTEINS, LDL; MOLECULAR SEQUENCE DATA; NASOPHARYNGEAL NEOPLASMS; PHOSPHATIDYLSERINES; PROTEIN BINDING; RECEPTORS, SCAVENGER; TUMOR NECROSIS FACTOR-ALPHA;

CYTOMEGALOVIRUS; LENTIVIRUS; MAMMALIA;

EID: 33947277482     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1111/j.1745-7270.2007.00264.x     Document Type: Article

References (19)

1. Ross R. The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature 1993, 362: 801-809
2. Ross R. Atherosclerosis - an inflammatory disease. N Eng J Med 1999, 340: 115-126
3. Leskinen MJ, Kovanen PT, Lindstedt KA. Regulation of smooth muscle cell growth, function and death in vitro by activated mast cells - α potential mechanism for the weakening and rupture of atherosclerotic plaques. Biochem Pharmacol 2003, 66: 1493-1498
4. Steinke JW, Borish L. Cytokines and chemokines. J Allergy Clin Immunol 2006, 117: 8441-8445
5. Sheikine YA, Hansson GK. Chemokines as potential therapeutic targets in atherosclerosis. Curr Drug Targets 2006, 7: 13-27
6. Getz GS. Thematic review series: The immune system and atherogenesis. Immune function in atherogenesis. J Lipid Res 2005, 46: 1-10
7. Mandai K, Jahangiri M, Xu Q. Autoimmune mechanisms of atherosclerosis. Handb Exp Pharmacol 2005, 170: 723-743
8. Matloubian M, David A, Engel S, Ryan JE, Cyster JG. A transmembrane CXC cheraokine is a ligand for HIV-coreceptor Bonzo. Nat Immunol 2000, 1: 298-304
9. Minami M, Kume N, Shimaoka T, Kataoka H, Hayashida K, Akiyama Y, Nagata I et al. Expression of SR-PSOX, a novel cell-surface scavenger receptor for phosphatidylserine and oxidized LDL in human atherosclerotic lesions. Arterioscler Thromb Vasc Biol 2001, 21: 1796-1800
10. Shimaoka T, Nakayama T, Kume N, Takahashi S, Yamaguchi J, Minami M, Hayashida K et al. Cutting edge: SR-PSOX/CXC chemokine ligand 16 mediates bacterial phagocytosis by APCs through its chemokine domain. J Immunol 2003, 171: 1647-1651
11. Yang HL, Jiang HJ, Fang WY, Xu YY, Liao DF, He FC. High fidelity PCR with an off/on switch mediated by proofreading polymerases combining with phosphorothioate modified primer. Biochem Biophys Res Commun 2005, 328: 265-272
12. Xu YY, Yang HL, Tu J, He SY, Liao DF. Construction, identification and primary functional analysis of pcDNA3. 1/NT-GFP-caveolin-l and mutant plasmids. Chin J Arterioscler 2005, 13: 297-300
13. Xu YY, Yang HL, You Y, Qin L, Tu J. A reverse transcriptase polymerase chain reaction method improving the specific amplification of caveolin-1 gene sequences. Chin J Med Genet 2006, 1: 59-62
14. Blesch A. Lentiviral and MLVbased retroviral vectors for ex vivo and in vivo gene transfer. Methods 2004, 33: 164-172
15. Delenda C. Lentiviral vectors: Optimization of packaging, transduction and gene expression. J Gene Med 2004, 1: S125-S138
16. Gough PJ, Garton KJ, Wille PT, Rychlewski M, Dempsey PJ, Raines EW. A disintegrin and metalloproteinase 10-mediated cleavage and shedding regulates the cell surface expression of CXC chemokine ligand 16. J Immunol 2004, 172: 3678-3685
17. Abel S, Hundhausen C, Mentlein R, Schulte A, Berkhout TA, Broadway N, Hartmann D et al. The transmembrane CXC-chemokine ligand 16 is induced by IFN-γ and TNF-α and shed by the activity of the disintegrin-like metalloproteinase ADAM10. J Immunol 2004, 172: 6362-6372
18. Sheikine Y, Hansson GK. Chemokines and atherosclerosis. Ann Med 2004, 36: 98-118
19. Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. Increased adipose tissue expression of TNF-α in human obesity and insulin resistance. J Clin Invest 1995, 95: 2409