TAP expression reduces IL-10 expressing tumor infiltrating lymphocytes and restores immunosurveillance against melanoma

International Journal of Cancer

Volumn 120, Issue 9, 2007, Pages 1935-1941

  Zhang, Qian Jin ^a,c   Seipp, Robyn P ^a,b   Chen, Susan S ^a,b   Vitalis, Timothy Z ^a   Li, Xiao Lin ^a,c   Choi, Kyung Bok ^a,b   Jeffries, Andrew ^a,b   Jefferies, Wilfred A ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

B16F10; Melanoma; MHC class I; Mouse; TAP1; Vaccinia

Indexed keywords

CARRIER PROTEIN; CD3 ANTIGEN; INTERLEUKIN 10; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 1; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 2; UNCLASSIFIED DRUG; VACCINIA VIRUS VECTOR; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; CANCER MODEL; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DOWN REGULATION; IMMUNOGENICITY; IMMUNOSUPPRESSIVE TREATMENT; IMMUNOSURVEILLANCE; IRRADIATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MELANOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR ASSOCIATED LEUKOCYTE;

ANIMALS; ANTIGEN PRESENTATION; ATP-BINDING CASSETTE TRANSPORTERS; H-2 ANTIGENS; HISTOCOMPATIBILITY ANTIGENS CLASS II; INTERLEUKIN-10; LYMPHOCYTES, TUMOR-INFILTRATING; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL;

EID: 33947267156     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.22371     Document Type: Article

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