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Volumn 25, Issue 1, 2007, Pages 59-66

Role of pemetrexed in non-small cell lung cancer

Author keywords

Non small cell lung cancer; Permetraxed

Indexed keywords

BEVACIZUMAB; CARBOPLATIN; CISPLATIN; CYANOCOBALAMIN; DIHYDROFOLATE REDUCTASE; DOCETAXEL; DOXORUBICIN; FLUOROURACIL; FOLIC ACID; GEMCITABINE; IRINOTECAN; METHOTREXATE; NAVELBINE; OXALIPLATIN; PACLITAXEL; PEMETREXED; PLATINUM DERIVATIVE; RALTITREXED; RETROVIRUS VECTOR; THYMIDYLATE SYNTHASE;

EID: 33947238447     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.1080/07357900601130748     Document Type: Review
Times cited : (21)

References (50)
  • 1
    • 2942657615 scopus 로고    scopus 로고
    • Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
    • Johnson, D.H.; Fehrenbacher, L.; Novotny, W.F.; et al. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J. Clin. Oncol. 2004, 22, 2184-2191.
    • (2004) J. Clin. Oncol , vol.22 , pp. 2184-2191
    • Johnson, D.H.1    Fehrenbacher, L.2    Novotny, W.F.3
  • 2
    • 1042301957 scopus 로고    scopus 로고
    • The role of alpha-folate receptor-mediated transport in the antitumor activity of antifolate drugs
    • Theti, D.S.; Jackman, A.L. The role of alpha-folate receptor-mediated transport in the antitumor activity of antifolate drugs. Clin. Cancer. Res. 2004, 10, 1080-1089.
    • (2004) Clin. Cancer. Res , vol.10 , pp. 1080-1089
    • Theti, D.S.1    Jackman, A.L.2
  • 3
    • 14644392093 scopus 로고    scopus 로고
    • Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay
    • Parker, N.; Turk, M.J.; Westrick, E.; Lewis, J.D.; Low, P.S.; Leamon, C.P. Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay. Anal. Biochem. 2005, 338, 284-293.
    • (2005) Anal. Biochem , vol.338 , pp. 284-293
    • Parker, N.1    Turk, M.J.2    Westrick, E.3    Lewis, J.D.4    Low, P.S.5    Leamon, C.P.6
  • 4
    • 0032898580 scopus 로고    scopus 로고
    • Role of the thymidylate synthase in the antitumor activity of the multitargeted antifolate LY231514
    • Schultz, R.M.; Patel, V.F.; Worzalla, J.F.; Shih, C. Role of the thymidylate synthase in the antitumor activity of the multitargeted antifolate LY231514. Anticancer Research 1999, 19, 437-443.
    • (1999) Anticancer Research , vol.19 , pp. 437-443
    • Schultz, R.M.1    Patel, V.F.2    Worzalla, J.F.3    Shih, C.4
  • 6
    • 0034060265 scopus 로고    scopus 로고
    • Treatment regimens including the multitargeted antifolate LY231514 in human tumor xenograft
    • Teicher, B.A.; Chen, V.; Shih, C.; Menon, K.; Forler, P.A.; Phares, V.G.; Amsrud, T. Treatment regimens including the multitargeted antifolate LY231514 in human tumor xenograft. Clin. Cancer Res. 2000, 6, 1016-1023.
    • (2000) Clin. Cancer Res , vol.6 , pp. 1016-1023
    • Teicher, B.A.1    Chen, V.2    Shih, C.3    Menon, K.4    Forler, P.A.5    Phares, V.G.6    Amsrud, T.7
  • 8
    • 0032964203 scopus 로고    scopus 로고
    • Teicher, B.A.; Alvarez, E.; Liu, P.; Lu, K.; Menon, K.; Dempsey, J.; Schultz, R.M. MTA (LY231514) in combination treatment regimens using human tumor xenografts and the EMT-6 murine mammary carcinoma. Semin. Oncol. 1999, 26 (Suppl. 6), 55-56.
    • Teicher, B.A.; Alvarez, E.; Liu, P.; Lu, K.; Menon, K.; Dempsey, J.; Schultz, R.M. MTA (LY231514) in combination treatment regimens using human tumor xenografts and the EMT-6 murine mammary carcinoma. Semin. Oncol. 1999, 26 (Suppl. 6), 55-56.
  • 9
    • 0033179374 scopus 로고    scopus 로고
    • Cell cycle modulation by a multitargeted antifolate, LY231514, increases the cytotoxicity and antitumor activity of gemcitabine in HT29 colon carcinoma
    • Tonkinson, J.L.; Worzalla, J.F.; Teng, C.H.; Mendelsohn, L.G. Cell cycle modulation by a multitargeted antifolate, LY231514, increases the cytotoxicity and antitumor activity of gemcitabine in HT29 colon carcinoma. Cancer Res. 1999, 59, 3671-3676.
    • (1999) Cancer Res , vol.59 , pp. 3671-3676
    • Tonkinson, J.L.1    Worzalla, J.F.2    Teng, C.H.3    Mendelsohn, L.G.4
  • 10
    • 0036155290 scopus 로고    scopus 로고
    • In vitro schedule-dependent interactions between the multitargeted antifolate LY231514 and gemcitabine in human colon adenocarcinoma cell lines
    • Tesei, A.; Ricotti, L.; De Paola, F.; Amadori, D.; Frassinetti, G.L. In vitro schedule-dependent interactions between the multitargeted antifolate LY231514 and gemcitabine in human colon adenocarcinoma cell lines. Clin. Cancer Res. 2002, 8, 233-239.
    • (2002) Clin. Cancer Res , vol.8 , pp. 233-239
    • Tesei, A.1    Ricotti, L.2    De Paola, F.3    Amadori, D.4    Frassinetti, G.L.5
  • 11
    • 0034327360 scopus 로고    scopus 로고
    • Equilibrative-sensitive nucleoside transporter and its role in gemcitabine sensitivity
    • Rauchwerger, D.R.; Firby, P.S.; Hedley, D.W.; Moore, M.J. Equilibrative-sensitive nucleoside transporter and its role in gemcitabine sensitivity. Cancer Res. 2000, 60, 6075-6079.
    • (2000) Cancer Res , vol.60 , pp. 6075-6079
    • Rauchwerger, D.R.1    Firby, P.S.2    Hedley, D.W.3    Moore, M.J.4
  • 12
    • 2442451440 scopus 로고    scopus 로고
    • Synergistic cytotoxicity and pharmacogenetics of gemcitabine and pemetrexed combination in pancreatic cancer cell lines
    • Giovannetti, E.; Mey, V.; Danesi, R.; Mosca, I.; Del Tacca. M. Synergistic cytotoxicity and pharmacogenetics of gemcitabine and pemetrexed combination in pancreatic cancer cell lines. Cancer Res. 2004, 10, 2936-2943.
    • (2004) Cancer Res , vol.10 , pp. 2936-2943
    • Giovannetti, E.1    Mey, V.2    Danesi, R.3    Mosca, I.4    Del Tacca, M.5
  • 13
    • 22344449812 scopus 로고    scopus 로고
    • Cellular and pharmacogenetics foundation of Synergistic interaction of pemetrexed and gemcitabine in human non-small cell lung cancer cells
    • Giovannetti, E.; Mey, V.; Nannizzi, S.; Pasqualetti, G.; Marini, L.; Del Tacca, M.; Danesi, R. Cellular and pharmacogenetics foundation of Synergistic interaction of pemetrexed and gemcitabine in human non-small cell lung cancer cells. Mol. Pharmacol. 2005, 68, 110-118.
    • (2005) Mol. Pharmacol , vol.68 , pp. 110-118
    • Giovannetti, E.1    Mey, V.2    Nannizzi, S.3    Pasqualetti, G.4    Marini, L.5    Del Tacca, M.6    Danesi, R.7
  • 14
    • 0036562507 scopus 로고    scopus 로고
    • Homocysteine and methylmalonic acid: Markers to predict and avoid toxicity from pemetrexed therapy
    • Niyikiza, C.; Baker, S.D.; Seitz, D.E.; et al. Homocysteine and methylmalonic acid: markers to predict and avoid toxicity from pemetrexed therapy. Mol. Cancer Ther. 2002, 1, 545-552.
    • (2002) Mol. Cancer Ther , vol.1 , pp. 545-552
    • Niyikiza, C.1    Baker, S.D.2    Seitz, D.E.3
  • 15
    • 10744219945 scopus 로고    scopus 로고
    • Phase II study of pemetrexed disodium (Alimta) administered with oral folic acid in patients with advanced gastric cancer
    • Bajetta, E.; Celio, L.; Buzzoni, R.; et al. Phase II study of pemetrexed disodium (Alimta) administered with oral folic acid in patients with advanced gastric cancer. Ann. Oncol. 2003, 14, 1543-1548.
    • (2003) Ann. Oncol , vol.14 , pp. 1543-1548
    • Bajetta, E.1    Celio, L.2    Buzzoni, R.3
  • 16
    • 0037386688 scopus 로고    scopus 로고
    • Is the measurement of thymidylate synthase to determine suitability for treatment with 5-fluoropyrimidines ready for prime time?
    • Bertino, J.R.; Banerjee, D. Is the measurement of thymidylate synthase to determine suitability for treatment with 5-fluoropyrimidines ready for prime time? Clin. Cancer Res. 2003, 4, 1235-1239.
    • (2003) Clin. Cancer Res , vol.4 , pp. 1235-1239
    • Bertino, J.R.1    Banerjee, D.2
  • 17
    • 0037317004 scopus 로고    scopus 로고
    • Thymidylate synthase expression in advanced colorectal cancer predicts for response to raltitrexed
    • Farrugia, D.C.; Ford, H.E.; Cunningham, D.; et al. Thymidylate synthase expression in advanced colorectal cancer predicts for response to raltitrexed. Clin. Cancer Res. 2003, 9, 792-801.
    • (2003) Clin. Cancer Res , vol.9 , pp. 792-801
    • Farrugia, D.C.1    Ford, H.E.2    Cunningham, D.3
  • 18
    • 0027175376 scopus 로고
    • Homozygous loss of the interferon genes defines the critical region on 9p that is deleted in lung cancers
    • Olopade, O.I.; Buchhagen D.L.; Malik, K.; et al. Homozygous loss of the interferon genes defines the critical region on 9p that is deleted in lung cancers. Cancer Res. 1993, 53 (10 Suppl), 2410-2415.
    • (1993) Cancer Res , vol.53 , Issue.10 SUPPL. , pp. 2410-2415
    • Olopade, O.I.1    Buchhagen, D.L.2    Malik, K.3
  • 19
    • 0032908148 scopus 로고    scopus 로고
    • Multitargeted antifolate LY231514 as first-line chemotherapy for patients with advanced non-small-cell lung cancer: A phase II study. National Cancer Institute of Canada Clinical Trials Group
    • Rusthoven, J.J.; Eisenhauer, E.; Butts, C.; Gregg, R.; Dancey, J.; Fisher, B.; Iglesias, J. Multitargeted antifolate LY231514 as first-line chemotherapy for patients with advanced non-small-cell lung cancer: a phase II study. National Cancer Institute of Canada Clinical Trials Group. J. Clin. Oncol. 1999, 17, 1194-1199.
    • (1999) J. Clin. Oncol , vol.17 , pp. 1194-1199
    • Rusthoven, J.J.1    Eisenhauer, E.2    Butts, C.3    Gregg, R.4    Dancey, J.5    Fisher, B.6    Iglesias, J.7
  • 20
    • 0035985288 scopus 로고    scopus 로고
    • Phase II trial of pemetrexed disodium (Alimta, (LY 231514) in chemotherapy-native patients with advanced non-small-cell lung cancer
    • Clarke, S.J.; Abratt, R.; Goedhals, L.; Boyer, M.J.; Millward, M.J.; Ackland, S.P. Phase II trial of pemetrexed disodium (Alimta, (LY 231514) in chemotherapy-native patients with advanced non-small-cell lung cancer. Ann. Oncol. 2002, 13, 737-741.
    • (2002) Ann. Oncol , vol.13 , pp. 737-741
    • Clarke, S.J.1    Abratt, R.2    Goedhals, L.3    Boyer, M.J.4    Millward, M.J.5    Ackland, S.P.6
  • 21
    • 0037352426 scopus 로고    scopus 로고
    • Postmus, P.E. ALIMTA (pemetrexed disodium) as second-line treatment of non-small-cell lung cancer: A phase II study
    • Smit, E.F.; Mattson, K.; von Pawel, J.; Manegold, C.; Clarcke, S.; Postmus, P.E. ALIMTA (pemetrexed disodium) as second-line treatment of non-small-cell lung cancer: a phase II study. Ann. Oncol. 2003, 14, 455-460.
    • (2003) Ann. Oncol , vol.14 , pp. 455-460
    • Smit, E.F.1    Mattson, K.2    von Pawel, J.3    Manegold, C.4    Clarcke, S.5
  • 22
    • 2442661845 scopus 로고    scopus 로고
    • Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy
    • Hanna, N.; Shepherd, F.A.; Fossella, F.V.; et al. Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy. J. Clin. Oncol. 2004, 22, 1589-1597.
    • (2004) J. Clin. Oncol , vol.22 , pp. 1589-1597
    • Hanna, N.1    Shepherd, F.A.2    Fossella, F.V.3
  • 23
    • 22244446806 scopus 로고    scopus 로고
    • FDA drug approval summary: Pemetrexed for injection (Alimta) for the treatment of non-small cell lung cancer
    • Cohen, M.H.; Johnson, J.R.; Wang, Y-C.; Sridara, R.; Pazdur, R. FDA drug approval summary: pemetrexed for injection (Alimta) for the treatment of non-small cell lung cancer. The Oncologist 2005, 10, 363-368.
    • (2005) The Oncologist , vol.10 , pp. 363-368
    • Cohen, M.H.1    Johnson, J.R.2    Wang, Y.-C.3    Sridara, R.4    Pazdur, R.5
  • 24
    • 0033993714 scopus 로고    scopus 로고
    • Phase I and pharmacologic study of sequences of gemcitabine and the multitargeted antifolate agent in patients with advanced solid tumor
    • Adjei, A.A.; Erlichman, C.; Sloan, J.A.; et al. Phase I and pharmacologic study of sequences of gemcitabine and the multitargeted antifolate agent in patients with advanced solid tumor. J. Clin. Oncol. 2000, 18, 1748-1757.
    • (2000) J. Clin. Oncol , vol.18 , pp. 1748-1757
    • Adjei, A.A.1    Erlichman, C.2    Sloan, J.A.3
  • 25
    • 0344980120 scopus 로고    scopus 로고
    • Clinical and pharmacokinetic phase I study of multitargeted antifolate (LY231514) in combination with cisplatin
    • Thodtman, R.; Depenbrock, H.; Dumez, H.; Blatter, J.; Johnson, R.D.; van Oosterom, A.; Hanauske, A.R. Clinical and pharmacokinetic phase I study of multitargeted antifolate (LY231514) in combination with cisplatin. J. Clin. Oncol. 1999, 17, 3009-3016.
    • (1999) J. Clin. Oncol , vol.17 , pp. 3009-3016
    • Thodtman, R.1    Depenbrock, H.2    Dumez, H.3    Blatter, J.4    Johnson, R.D.5    van Oosterom, A.6    Hanauske, A.R.7
  • 26
    • 20244374653 scopus 로고    scopus 로고
    • Phase I clinical and pharmacokinetic study of pemetrexed and carboplatin in patients with malignant pleural mesothelioma
    • Hughes, A.; Calvert, P.; Azzabi, A.; et al. Phase I clinical and pharmacokinetic study of pemetrexed and carboplatin in patients with malignant pleural mesothelioma. J. Clin. Oncol. 2002, 20, 3533-3544.
    • (2002) J. Clin. Oncol , vol.20 , pp. 3533-3544
    • Hughes, A.1    Calvert, P.2    Azzabi, A.3
  • 27
    • 4143093793 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of the multitargeted antifolate pemetrexed in combination with oxaliplatin in patients with advanced solid tumors
    • Missett, J.L.; Gamelin, E.; Campone, M.; Delaloge, S.; Latz, J.E.; Bozec, L.; Fumoleau, P. Phase I and pharmacokinetic study of the multitargeted antifolate pemetrexed in combination with oxaliplatin in patients with advanced solid tumors. Ann. Oncol. 2004, 15, 1123-1129.
    • (2004) Ann. Oncol , vol.15 , pp. 1123-1129
    • Missett, J.L.1    Gamelin, E.2    Campone, M.3    Delaloge, S.4    Latz, J.E.5    Bozec, L.6    Fumoleau, P.7
  • 28
    • 17644420937 scopus 로고    scopus 로고
    • Phase I study of pemetrexed in combination with docetaxel in patients with advanced solid malignancies
    • Mackay, H.; Carmichael, J.; Roberts, J.; et al. Phase I study of pemetrexed in combination with docetaxel in patients with advanced solid malignancies. Proc Am. Soc. Clin. Oncol. 2002, 21, 77b.
    • (2002) Proc Am. Soc. Clin. Oncol , vol.21
    • Mackay, H.1    Carmichael, J.2    Roberts, J.3
  • 29
    • 23744482948 scopus 로고    scopus 로고
    • A phase I/II study of pemetrexed and vinorelbine in patients with non-small cell lung cancer
    • Clarke, S.J.; Boyer, M.J.; Millward, M.; et al. A phase I/II study of pemetrexed and vinorelbine in patients with non-small cell lung cancer. Lung Cancer 2005, 49, 401-412.
    • (2005) Lung Cancer , vol.49 , pp. 401-412
    • Clarke, S.J.1    Boyer, M.J.2    Millward, M.3
  • 30
    • 0034029995 scopus 로고    scopus 로고
    • Front-line treatment of advanced non small-cell lung cancer with MTA (LY231514, pemetrexed disodium, ALIMTA) and cisplatin: A multicenter phase II trial
    • Manegold, C.; Gatzemeier, U.; von Pawel J.; Pirker, R.; Malayeri, R.; Blatter, J.; Krejcy, K. Front-line treatment of advanced non small-cell lung cancer with MTA (LY231514, pemetrexed disodium, ALIMTA) and cisplatin: a multicenter phase II trial. Ann. Oncol. 2000, 11, 435-440.
    • (2000) Ann. Oncol , vol.11 , pp. 435-440
    • Manegold, C.1    Gatzemeier, U.2    von Pawel, J.3    Pirker, R.4    Malayeri, R.5    Blatter, J.6    Krejcy, K.7
  • 31
    • 0035423962 scopus 로고    scopus 로고
    • Phase II study of pemetrexed disodium, a multitargeted antifolate, and cisplatin as first-line therapy in patients with advanced non-small cell lung carcinoma: A study of the National Cancer Institute of Canada Clinical Trial Group
    • Shepherd, F.A.; Dancey, J.; Arnold, A.; et al. Phase II study of pemetrexed disodium, a multitargeted antifolate, and cisplatin as first-line therapy in patients with advanced non-small cell lung carcinoma: a study of the National Cancer Institute of Canada Clinical Trial Group. Cancer 2001, 92, 595-600.
    • (2001) Cancer , vol.92 , pp. 595-600
    • Shepherd, F.A.1    Dancey, J.2    Arnold, A.3
  • 32
    • 28044463139 scopus 로고    scopus 로고
    • Phase II study of pemetrexed in combination with carboplatin in the first-line treatment of advanced nonsmall cell lung cancer
    • Zinner, R.G.; Fossella, F.V.; Gladish, G.W.; et al. Phase II study of pemetrexed in combination with carboplatin in the first-line treatment of advanced nonsmall cell lung cancer. Cancer 2005, 104, 2449-2456.
    • (2005) Cancer , vol.104 , pp. 2449-2456
    • Zinner, R.G.1    Fossella, F.V.2    Gladish, G.W.3
  • 33
    • 19944426696 scopus 로고    scopus 로고
    • Pemetrexed combined with oxaliplatin or carboplatin as first-line treatment in advanced non-small cell lung cancer: A multicenter, randomized, phase II trial
    • Scagliotti, G.V.; Korstsik, C.; Dark, G.G.; et al. Pemetrexed combined with oxaliplatin or carboplatin as first-line treatment in advanced non-small cell lung cancer: a multicenter, randomized, phase II trial. Clin. Cancer Res. 2005, 11, 690-696.
    • (2005) Clin. Cancer Res , vol.11 , pp. 690-696
    • Scagliotti, G.V.1    Korstsik, C.2    Dark, G.G.3
  • 34
    • 4143132166 scopus 로고    scopus 로고
    • Phase II study of pemtrexed-gemcitabine combination in patients with advanced-stage non-small cell lung cancer
    • Monnerat, C.; Le Chevalier, T.; Kelly, K.; et al. Phase II study of pemtrexed-gemcitabine combination in patients with advanced-stage non-small cell lung cancer. Clin. Cancer Res. 2004, 10, 5439-5446.
    • (2004) Clin. Cancer Res , vol.10 , pp. 5439-5446
    • Monnerat, C.1    Le Chevalier, T.2    Kelly, K.3
  • 35
    • 24944485165 scopus 로고    scopus 로고
    • Randomized phase II trial of three schedules of pemetrexed and gemcitabine as front-line therapy for advanced non-small cell lung cancer
    • Ma, C.X.; Nair, S.; Thomas, S.; et al. Randomized phase II trial of three schedules of pemetrexed and gemcitabine as front-line therapy for advanced non-small cell lung cancer. J. Clin. Oncol. 2005, 23, 5929-5937.
    • (2005) J. Clin. Oncol , vol.23 , pp. 5929-5937
    • Ma, C.X.1    Nair, S.2    Thomas, S.3
  • 36
    • 0035397994 scopus 로고    scopus 로고
    • Randomized phase III trial of paclitaxel plus carboplatin versus vinorelbine plus cisplatin in the treatment of patients with advanced non-small-cell lung cancer: A Southwest Oncology Group trial
    • Kelly, K.; Crowley, J.; Bunn, P.A., Jr.; et al. Randomized phase III trial of paclitaxel plus carboplatin versus vinorelbine plus cisplatin in the treatment of patients with advanced non-small-cell lung cancer: a Southwest Oncology Group trial. J. Clin. Oncol. 2001, 19, 3210-3218.
    • (2001) J. Clin. Oncol , vol.19 , pp. 3210-3218
    • Kelly, K.1    Crowley, J.2    Bunn Jr., P.A.3
  • 37
    • 0037050352 scopus 로고    scopus 로고
    • Eastern Cooperative Oncology Group. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
    • Schiller, J.H.; Harrington, D.; Belani, C.P.; et al. Eastern Cooperative Oncology Group. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N. Engl. J. Med. 2002, 346, 92-98.
    • (2002) N. Engl. J. Med , vol.346 , pp. 92-98
    • Schiller, J.H.1    Harrington, D.2    Belani, C.P.3
  • 38
    • 0036843105 scopus 로고    scopus 로고
    • Italian Lung Cancer Project. Phase III randomized trial comparing three platinum-based doublets in advanced non-small-cell lung cancer
    • Scagliotti, G.V.; De Marinis, F.; Rinaldi, M.; et al. Italian Lung Cancer Project. Phase III randomized trial comparing three platinum-based doublets in advanced non-small-cell lung cancer. J. Clin. Oncol. 2002, 20, 4285-4291.
    • (2002) J. Clin. Oncol , vol.20 , pp. 4285-4291
    • Scagliotti, G.V.1    De Marinis, F.2    Rinaldi, M.3
  • 39
    • 0042413836 scopus 로고    scopus 로고
    • Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small-cell lung cancer: The TAX 326 study group
    • Fossella, F.; Pereira, J.R.; von Pawel, J.; et al. Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small-cell lung cancer: the TAX 326 study group. J. Clin. Oncol. 2003, 21, 3016-3024.
    • (2003) J. Clin. Oncol , vol.21 , pp. 3016-3024
    • Fossella, F.1    Pereira, J.R.2    von Pawel, J.3
  • 40
    • 0037037807 scopus 로고    scopus 로고
    • Recent advances in the molecular diagnosis of lung cancer
    • Mao, L. Recent advances in the molecular diagnosis of lung cancer. Oncogene 2002, 21, 6960-6969.
    • (2002) Oncogene , vol.21 , pp. 6960-6969
    • Mao, L.1
  • 41
    • 0026425629 scopus 로고
    • Ras gene mutations in non-small cell lung cancers are associated with shortened survival irrespective of treatment intent
    • Mitsudomi, T.; Steinberg, S.M.; Oie, H.K.; et al. Ras gene mutations in non-small cell lung cancers are associated with shortened survival irrespective of treatment intent. Cancer Res. 1991, 51, 4999-5002.
    • (1991) Cancer Res , vol.51 , pp. 4999-5002
    • Mitsudomi, T.1    Steinberg, S.M.2    Oie, H.K.3
  • 42
    • 0036534381 scopus 로고    scopus 로고
    • Trimodality treatment in stage III non-small cell lung carcinoma: Prognostic impact of K-ras mutations after neoadjuvant therapy
    • Broermann, P.; Junker, K.; Brandt, B.H.; Heinecke, A.; Freitag, L.; Berdel, W.E.; Thomas, M. Trimodality treatment in stage III non-small cell lung carcinoma: prognostic impact of K-ras mutations after neoadjuvant therapy. Cancer 2002, 94, 2055-2062.
    • (2002) Cancer , vol.94 , pp. 2055-2062
    • Broermann, P.1    Junker, K.2    Brandt, B.H.3    Heinecke, A.4    Freitag, L.5    Berdel, W.E.6    Thomas, M.7
  • 43
    • 0033899212 scopus 로고    scopus 로고
    • Retinoic acid receptor-beta as a prognostic indicator in stage I non-small cell lung cancer
    • Khuri, F.R.; Lotan, R.; Kemp, B.L.; et al. Retinoic acid receptor-beta as a prognostic indicator in stage I non-small cell lung cancer. J. Clin. Oncol. 2000, 18, 2798-2804.
    • (2000) J. Clin. Oncol , vol.18 , pp. 2798-2804
    • Khuri, F.R.1    Lotan, R.2    Kemp, B.L.3
  • 44
    • 0034901568 scopus 로고    scopus 로고
    • Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer
    • Khuri, F.R.; Wu, H.; Lee, J.J.; et al. Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer. Clin. Cancer Res. 2001, 7, 861-867.
    • (2001) Clin. Cancer Res , vol.7 , pp. 861-867
    • Khuri, F.R.1    Wu, H.2    Lee, J.J.3
  • 45
    • 0035913647 scopus 로고    scopus 로고
    • Collapsin response mediator protein-1 and the invasion and metastasis of cancer cells
    • Shih, J.Y.; Yang, S.C.; Hong, T.M.; et al. Collapsin response mediator protein-1 and the invasion and metastasis of cancer cells. J. Natl. Cancer Inst. 2001, 93, 1392-1400.
    • (2001) J. Natl. Cancer Inst , vol.93 , pp. 1392-1400
    • Shih, J.Y.1    Yang, S.C.2    Hong, T.M.3
  • 46
    • 0033694997 scopus 로고    scopus 로고
    • Interleukin-8 messenger ribonuclein acid expression correlates with tumor progression, tumor angiogenesis, patient survival, and timing of relapse in non-small cell lung cancer
    • Yuan, A.; Yang, P.C.; Yu, C.J.; Chen, W.J.; Lin, F.Y.; Kuo, S.H.; Luh, K.T. Interleukin-8 messenger ribonuclein acid expression correlates with tumor progression, tumor angiogenesis, patient survival, and timing of relapse in non-small cell lung cancer. Am. J. Respir. Crit. Care Med. 2000, 162, 1957-1963.
    • (2000) Am. J. Respir. Crit. Care Med , vol.162 , pp. 1957-1963
    • Yuan, A.1    Yang, P.C.2    Yu, C.J.3    Chen, W.J.4    Lin, F.Y.5    Kuo, S.H.6    Luh, K.T.7
  • 47
    • 0038666325 scopus 로고    scopus 로고
    • Lack of interleukin-10 could predict poor outcome in patients with stage I non-small cell lung cancer
    • Soria, J.C.; Moon, C.; Kemp, B.L.; et al. Lack of interleukin-10 could predict poor outcome in patients with stage I non-small cell lung cancer. Clin. Cancer Res. 2003, 9, 1785-1791.
    • (2003) Clin. Cancer Res , vol.9 , pp. 1785-1791
    • Soria, J.C.1    Moon, C.2    Kemp, B.L.3
  • 48
    • 0036498729 scopus 로고    scopus 로고
    • Prognostic significance of molecular genetic aberrations on chromosome segment 11p15.5 in non-small cell lung cancer
    • Bepler, G.; Gautam, A.; McIntyre, L.M.; et al. Prognostic significance of molecular genetic aberrations on chromosome segment 11p15.5 in non-small cell lung cancer. J. Clin. Oncol. 2002, 20, 1353-1360.
    • (2002) J. Clin. Oncol , vol.20 , pp. 1353-1360
    • Bepler, G.1    Gautam, A.2    McIntyre, L.M.3
  • 49
    • 10444284351 scopus 로고    scopus 로고
    • Protection of hemopoietic stem cell from pemetrexed toxicity by retroviral gene transfer with a mutant dihydrofolate reductase-mutant thymidylate synthase fusion gene
    • Capiaux, G.M.; Budak-Alpdogan, T.; Alpdogan, O.; et al. Protection of hemopoietic stem cell from pemetrexed toxicity by retroviral gene transfer with a mutant dihydrofolate reductase-mutant thymidylate synthase fusion gene. Cancer Gene Therapy 2004, 11, 767-773.
    • (2004) Cancer Gene Therapy , vol.11 , pp. 767-773
    • Capiaux, G.M.1    Budak-Alpdogan, T.2    Alpdogan, O.3
  • 50
    • 0029163531 scopus 로고
    • Protection of mice from lethal doses of methotrexate by transplantation with transgenic marrow expressing drug-resistant dihydrofolate reductase activity
    • May, C.; Gunther, R.; McIvor, R.S. Protection of mice from lethal doses of methotrexate by transplantation with transgenic marrow expressing drug-resistant dihydrofolate reductase activity. Blood 1995, 86, 2439-2448.
    • (1995) Blood , vol.86 , pp. 2439-2448
    • May, C.1    Gunther, R.2    McIvor, R.S.3


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