메뉴 건너뛰기




Volumn 2, Issue 1, 2000, Pages 1-10

Comparison of methods for analyzing kinetic data from mechanism-based enzyme inactivation: Application to nitric oxide synthase

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; N(G) NITROARGININE METHYL ESTER; NG NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE;

EID: 33947235192     PISSN: 15221059     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (33)

References (24)
  • 1
    • 0015861774 scopus 로고
    • Relationship between the inhibition constant KI and the concentration of inhibitor which causes 50 per cent inhibition 150 of an enzymatic reaction
    • Cheng Y, Prusoff WH. Relationship between the inhibition constant KI and the concentration of inhibitor which causes 50 per cent inhibition 150 of an enzymatic reaction. Biochem Pharmacol. 1973;22:3099-3108.
    • (1973) Biochem Pharmacol , vol.22 , pp. 3099-3108
    • Cheng, Y.1    Prusoff, W.H.2
  • 2
    • 0027967765 scopus 로고
    • Potent and selective inhibition of human nitric oxide synthases. Selective inhibition of neuronal nitric oxide synthase by S-methyl-L-thiocitrulline and S-ethyl-L-thiocitrulline
    • Furfine ES, Harmon MF, Paith JE, Knowles, RG, Salter M, Kiff, RJ, et al. Potent and selective inhibition of human nitric oxide synthases. Selective inhibition of neuronal nitric oxide synthase by S-methyl-L-thiocitrulline and S-ethyl-L-thiocitrulline. J Biol Chem. 1994;269:26677-26683.
    • (1994) J Biol Chem , vol.269 , pp. 26677-26683
    • Furfine, E.S.1    Harmon, M.F.2    Paith, J.E.3    Knowles, R.G.4    Salter, M.5    Kiff, R.J.6
  • 3
    • 0028089793 scopus 로고
    • Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas
    • Garvey EP, Oplinger JA, Tanoury GJ, Sherman PA, Fowler M, Marshall S, et al. Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas. J Biol Chem. 1994;269:26669-26676.
    • (1994) J Biol Chem , vol.269 , pp. 26669-26676
    • Garvey, E.P.1    Oplinger, J.A.2    Tanoury, G.J.3    Sherman, P.A.4    Fowler, M.5    Marshall, S.6
  • 4
    • 0031040613 scopus 로고    scopus 로고
    • 1400W is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase in vitro and in vivo
    • Garvey EP, Oplinger JA, Furfine ES, Kiff RJ, Laszlo F, Whittle BJ, et al. 1400W is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase in vitro and in vivo. J Biol Chem. 1997;272:4959-4963.
    • (1997) J Biol Chem , vol.272 , pp. 4959-4963
    • Garvey, E.P.1    Oplinger, J.A.2    Furfine, E.S.3    Kiff, R.J.4    Laszlo, F.5    Whittle, B.J.6
  • 5
    • 0030935086 scopus 로고    scopus 로고
    • Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions
    • Bertz RJ, Granneman GR. Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions. Clin Pharmacokinet. 1997;32:210-258.
    • (1997) Clin Pharmacokinet , vol.32 , pp. 210-258
    • Bertz, R.J.1    Granneman, G.R.2
  • 6
    • 0026591810 scopus 로고
    • The first mechanism-based inactivators for angiotensin-converting enzyme
    • Ghosh SS, Said-Nejad O, Roestamadji J, Mobashery S. The first mechanism-based inactivators for angiotensin-converting enzyme. J Med Chem. 1992;35:4175-4179.
    • (1992) J Med Chem , vol.35 , pp. 4175-4179
    • Ghosh, S.S.1    Said-Nejad, O.2    Roestamadji, J.3    Mobashery, S.4
  • 7
    • 0026591809 scopus 로고
    • Synthesis of novel MPTP analogs as potential monoamine oxidase B MAO-B inhibitors
    • Kalgutkar AS, Castagnoli Jr N. Synthesis of novel MPTP analogs as potential monoamine oxidase B MAO-B inhibitors. J Med Chem. 1992;35:4165-4174.
    • (1992) J Med Chem , vol.35 , pp. 4165-4174
    • Kalgutkar, A.S.1    Castagnoli Jr., N.2
  • 8
    • 0028978215 scopus 로고
    • "Suicide" inactivation of prostaglandin 12 synthase: Characterization of mechanism-based inactivation with isolated enzyme and endothelial cells
    • Wade ML, Voelkel NF, Fitzpatrick FA. "Suicide" inactivation of prostaglandin 12 synthase: characterization of mechanism-based inactivation with isolated enzyme and endothelial cells. Arch Biochem Biophys. 1995;321:453-458.
    • (1995) Arch Biochem Biophys , vol.321 , pp. 453-458
    • Wade, M.L.1    Voelkel, N.F.2    Fitzpatrick, F.A.3
  • 9
    • 0030808463 scopus 로고    scopus 로고
    • Inactivation of nitric oxide synthase by substituted aminoguanidines and aminoisothioureas
    • Wolff DJ, Gauld DS, Neulander MJ, Southan G. Inactivation of nitric oxide synthase by substituted aminoguanidines and aminoisothioureas. J Pharmacol Exp Ther. 1997;283:265-273.
    • (1997) J Pharmacol Exp Ther , vol.283 , pp. 265-273
    • Wolff, D.J.1    Gauld, D.S.2    Neulander, M.J.3    Southan, G.4
  • 10
    • 0023761288 scopus 로고
    • Disruption of hepatic heme biosynthesis after interaction of xenobiotics with cytochrome P-450
    • Marks GS, McCluskey SA, Mackie JE, Riddick DS, James CA. Disruption of hepatic heme biosynthesis after interaction of xenobiotics with cytochrome P-450. FASEB J. 1988;2:2774-2783.
    • (1988) FASEB J , vol.2 , pp. 2774-2783
    • Marks, G.S.1    McCluskey, S.A.2    Mackie, J.E.3    Riddick, D.S.4    James, C.A.5
  • 11
    • 0024507387 scopus 로고
    • Oxidation of cycloalkylamines by cytochrome P-450. Mechanism-based inactivation, adduct formation, ring expansion, and nitrone formation
    • Bondon A, Macdonald TL, Harris TM, Guengerich FP. Oxidation of cycloalkylamines by cytochrome P-450. Mechanism-based inactivation, adduct formation, ring expansion, and nitrone formation. J Biol Chem. 1989;264:1988-1997.
    • (1989) J Biol Chem , vol.264 , pp. 1988-1997
    • Bondon, A.1    Macdonald, T.L.2    Harris, T.M.3    Guengerich, F.P.4
  • 12
    • 0021254807 scopus 로고
    • Mechanism-based enzyme inactivators
    • Rando RR. Mechanism-based enzyme inactivators. Pharmacol Rev. 1984;36:111-142.
    • (1984) Pharmacol Rev , vol.36 , pp. 111-142
    • Rando, R.R.1
  • 13
    • 0016184254 scopus 로고
    • Chemistry and enzymology of kcat inhibitors
    • Rando RR. Chemistry and enzymology of kcat inhibitors. Science. 1974;85:320-324.
    • (1974) Science , vol.85 , pp. 320-324
    • Rando, R.R.1
  • 15
    • 0028848093 scopus 로고
    • Cysteine 99 of endothelial nitric oxide synthase NOS-III is critical for tetrahydrobiopterin-dependent NOS-III stability and activity
    • Chen PF, Tsai AL, Wu KK. Cysteine 99 of endothelial nitric oxide synthase NOS-III is critical for tetrahydrobiopterin-dependent NOS-III stability and activity. Biochem Biophys Res Comm. 1995;215:1119-1129.
    • (1995) Biochem Biophys Res Comm , vol.215 , pp. 1119-1129
    • Chen, P.F.1    Tsai, A.L.2    Wu, K.K.3
  • 16
    • 73649151319 scopus 로고
    • Esters of methanesulfonic acid as irreversible inhibitors of Acetylcholinesterase
    • Kitz R, Wilson IB. Esters of methanesulfonic acid as irreversible inhibitors of Acetylcholinesterase. J Biol Chem. 1962;237:3245-3249.
    • (1962) J Biol Chem , vol.237 , pp. 3245-3249
    • Kitz, R.1    Wilson, I.B.2
  • 17
    • 77049143386 scopus 로고
    • The determination of enzyme inhibitor constants
    • Dixon M. The determination of enzyme inhibitor constants. Biochem J. 1952;55:170-171.
    • (1952) Biochem J , vol.55 , pp. 170-171
    • Dixon, M.1
  • 19
    • 0028978149 scopus 로고
    • N-nitro-L-arginine and N-monomethyl-L-arginine exhibit a different pattern of inactivation toward the three nitric oxide synthases
    • Reif DW, McCreedy SA. N-nitro-L-arginine and N-monomethyl-L-arginine exhibit a different pattern of inactivation toward the three nitric oxide synthases. Arch Biochem Biophys. 1995;320:170-176.
    • (1995) Arch Biochem Biophys , vol.320 , pp. 170-176
    • Reif, D.W.1    McCreedy, S.A.2
  • 20
    • 0026611295 scopus 로고
    • NG-allyl- And NG-cyclopropyl-L-arginine: Two novel inhibitors of macrophage nitric oxide synthase
    • Olken NM, Marietta MA. NG-allyl- and NG-cyclopropyl-L-arginine: two novel inhibitors of macrophage nitric oxide synthase. J Med Chem. 1992;35:1137-1144.
    • (1992) J Med Chem , vol.35 , pp. 1137-1144
    • Olken, N.M.1    Marietta, M.A.2
  • 21
  • 22
    • 0025332527 scopus 로고
    • Endothelial nitric oxide generating enzymes in the bovine aorta: Subcellular location and metabolic characterization
    • Boje KM, Fung HL. Endothelial nitric oxide generating enzymes in the bovine aorta: subcellular location and metabolic characterization. J Pharmacol Exp Ther. 1990;253:20-26.
    • (1990) J Pharmacol Exp Ther , vol.253 , pp. 20-26
    • Boje, K.M.1    Fung, H.L.2
  • 23
    • 0023442604 scopus 로고
    • Fitting curves to data using nonlinear regression: A practical and nonmathematical review
    • Motulsky HJ, Ransnas LA. Fitting curves to data using nonlinear regression: a practical and nonmathematical review. FASEB J. 1987;1:365-374.
    • (1987) FASEB J , vol.1 , pp. 365-374
    • Motulsky, H.J.1    Ransnas, L.A.2
  • 24
    • 0027339884 scopus 로고
    • NG-methyl-L-arginine functions as an alternate substrate and mechanism-based inhibitor of nitric oxide synthase
    • Olken NM, Marietta MA. NG-methyl-L-arginine functions as an alternate substrate and mechanism-based inhibitor of nitric oxide synthase. Biochemistry. 1993;32:9677-9685.
    • (1993) Biochemistry , vol.32 , pp. 9677-9685
    • Olken, N.M.1    Marietta, M.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.