Reduced expression of α-tocopherol-associated protein is associated with tumor cell proliferation and the increased risk of prostate cancer recurrence

Asian Journal of Andrology

Volumn 9, Issue 2, 2007, Pages 206-212

  Wen, Xing Qiao ^a   Li, Xiao Juan ^a   Su, Zu Lan ^a   Liu, Yong ^a   Zhou, Xiang Fu ^a   Cai, Yu Bin ^a   Huang, Wen Tao ^a   Gao, Xin ^a   Prins, Gail S ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

tocopherol associated protein; Prostate neoplasms; Recurrence; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ALPHA TOCOPHEROL ASSOCIATED PROTEIN; KI 67 ANTIGEN; PROSTATE SPECIFIC ANTIGEN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER GROWTH; CANCER RECURRENCE; CANCER STAGING; GLEASON SCORE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LYMPH NODE; MAJOR CLINICAL STUDY; MALE; METASTASIS; PROGNOSIS; PROSTATE CANCER; PROSTATECTOMY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RECURRENCE RISK; SEMINAL VESICLE; STATISTICAL ANALYSIS; TUMOR VOLUME;

AGED; CARRIER PROTEINS; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KI-67 ANTIGEN; LIPOPROTEINS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PROSTATIC NEOPLASMS; TRANS-ACTIVATORS;

EID: 33947212924     PISSN: 1008682X     EISSN: 17457262     Source Type: Journal    
DOI: 10.1111/j.1745-7262.2007.00236.x     Document Type: Article

References (20)

1. Zimmer S, Stocker A, Sarbolouki MN, Spycher SE, Sassoon J, Azzi A. A novel human tocopherol-associated protein: Cloning, in vitro expression, and characterization. J Biol Chem 2000; 275: 25672-80.
2. Ni J, Wen X, Yao J, Chang HC, Yin Y, Zhang M, et al. Tocopherol-associated protein suppresses prostate cancer cell growth by inhibition of the phosphoinositide 3-kinase pathway. Cancer Res 2005; 65: 9807-16.
3. Miyake H, Hara I, Kamidono S, Eto H. Oxidative DNA damage in patients with prostate cancer and its response to treatment. J Urol 2004; 171: 1533-6.
4. Kawanishi S, Hiraku Y, Pinlaor S, Ma N. Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis. Biol Chem 2006; 387: 365-72.
5. Jiang AL, Zhang PJ, Chen WW, Liu WW, Yu CX, Hu XY, et al. Effects of 9-cis retinoic acid on human homeobox gene NKX3.1 expression in prostate cancer cell line LNCaP. Asian J Androl 2006; 8: 435-41.
6. Heinonen OP, Albanes D, Virtamo J, Taylor PR, Huttunen JK, Hartman AM, et al. Prostate cancer and supplementation with α-tocopherol and α-carotene: Incidence and mortality in a controlled trial. J Natl Cancer Inst 1998; 90: 440-6.
7. Blatt DH, Leonard SW, Traber MG. Vitamin E kinetics and the function of tocopherol. Nutrition 2001; 17: 799-805.
8. Israel K, Sanders BG, Kline K. RRR-α-tocopheryl succinate inhibits the proliferation of human prostatic tumor cells with defective cell cycle/differentiation pathways. Nutr Cancer 1995; 24: 161-9.
9. Zhang Y, Ni J, Messing EM, Chang E, Yang C, Yeh S. Vitamin E succinate inhibits the function of androgen receptor and the expression of prostate-specific antigen in prostate cancer cells. Proc Natl Acad Sci USA 2002; 99: 7408-13.
10. Malafa MP, Fokum FD, Andoh J, Neitzel LT, Bandyopadhyay S, Zhan R, et al. Vitamin E succinate suppresses prostate tumor growth by inducing apoptosis. Int J Cancer 2006; 118: 2441-7.
11. Stapleton A, Zbell P, Kattan MW, Yang G, Wheeler TM, Scardino PT, et al. Assessment of the biologic markers p53, Ki-67, and apoptotic index as predictive indicators of prostate carcinoma recurrence after surgery. Cancer 1998; 82: 168-75.
12. Koochekpour S, Sartor O, Hiraiwa M, Lee TJ, Rayford W, Remmel N, et al. Saposin C stimulates growth and invasion, activates p42/44 and SAPK/JNK signaling pathways of MAPK and upregulates uPA/uPAR expression in prostate cancer and stromal cells. Asian J Androl 2005; 7: 147-58.
13. Yamauchi J, Iwamoto T, Kida S, Masushige S, Yamada K, Esashi T. Tocopherol-associated protein is a ligand-dependent transcriptional activator. Biochem Biophys Res Commun 2001; 285: 295-9.
14. Stocker A, Baumann U. Supernatant protein factor in complex with RRR-α-tocopherylquinone: A link between oxidized vitamin E and cholesterol biosynthesis. J Mol Biol 2003; 332: 759-65.
15. Wilson MJ, Kaye D, Smith WE, Quach HT, Sinha AA, Vatassery GT. Effect of vitamin E deficiency on the growth and secretory function of the rat prostatic complex. Exp Mol Pathol 2003; 74: 267-75.
16. Copp RP, Wisniewski T, Hentati F, Larnaout A, Ben Hamida, M, Kayden HJ. Localization of tocopherol transfer protein in the brains of patients with ataxia with vitamin E deficiency and other oxidative stress related neurodegenerative disorders. Brain Res 1999; 822: 80-7.
17. Terasawa Y, Ladha Z, Leonard SW, Morrow JD, Newland D, Sanan D, et al. Increased atherosclerosis in hyperlipidemic mice deficient in α-tocopherol transfer protein and vitamin E. Proc Natl Acad Sci USA 2000; 97: 13830-4.
18. De Francesco L. Prostate cancer prevention trial launched. Nat Med 2001; 7: 1076.
19. Xu XF, Zhou SW, Zhang X, Ye ZQ, Zhang JH, Ma X, et al. Prostate androgen-regulated gene: A novel potential target for androgen-independent prostate cancer therapy. Asian J Androl 2006; 8: 455-62.
20. Zhao ZG, Ma QZ, Xu CX. Abrogation of heat-shock protein (HSP) 70 expression induced cell growth inhibition and apoptosis in human androgen-independent prostate cancer cell line PC-3m. Asian J Androl 2004; 6: 319-24.