Progress in study on the chemical constituens about sesquiterpene lactones and steroidal saponins from genus Vernonia and their pharmacological activities

Zhongguo Zhongyao Zazhi

Volumn 32, Issue 1, 2007, Pages 10-17

  Liu, Qing Hua ^a,b   Yang, Jun Shan ^a   Suo, Mao Rong ^a  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b Beijing Gingko Group Biol Tech Co Ltd   (China)

Author keywords

Compositae; Pharmacological activities; Progress in study; Sesquiterpene lactones; Sterol saponins; Vernonia

Indexed keywords

EID: 33947193500     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Kupchan S M, Hemingway R G, Karim A, et al. Tumor Inhibitors. XLVII. vernodalin and vernomygdin, two new cytotoxic sesquiterpene lactones from Vernonia amygdalina Del[J]. J Org Chem, 1969,12:3908.
2. Magboul A Z I, Bashir A K, Khalid S A, et al. Antimicribial activity of vernolepin and vernodalin[J]. Fitoterapia, 1997,LXVIII(1):83.
3. Laekeman G M, Mertens J, Bult H, et al. Isolation and pharmacological characterization of vernolepin[J]. J Nat Prod, 1983,46(2):161.
4. Roos G, Prawat H, Walter C U, et al. New sesquiterpene lactones with antibacterial activity from Verninia fastigiata[J]. Planta Med, 1998,64:673.
5. Catalán C A N, Legname P C, Crist B V, et al. Glaucolides from Vernonia fulta[J]. Phytochemistry, 1985,24(9):2113.
6. Jakupovic J, Braruah R N, Chau T T V, et al. New vernolepin derivatives from Vernonia glabra and glaucolides from Vernonia scorpioides[J]. Planta Med, 1985,5:378.
7. Jakupovic J, Schmeda-Hirschmann G, Schuster A, et al. Hirsutinolides, glaucolides and sesquiterpene lactone from Vernonia species[J]. Phytochemistry, 1986,25(1):145.
8. Jakupovic J, Zdero Ch, Boeker R, et al. Vernocistifolide und andere sesquiterpenlactone aus Vernonia und Verwandten[J]. Liebigs Ann Vhem, 1987:111.
9. Catalán C A N, Iglesias D I A. Sesquiterpene lactones and other constituents of Vernonia mollissima and Vernonia squamulosa[J]. J Nat Prod, 1986,49(2):351.
10. Gasquet M, Bamba D, Babadjamian, et al. Action amoebicide et anthelminthique du vernolide et de hydroxyvernolide isolfe des feuilles de Vernonia colorata (Willd.) Drake[J]. Eur J Med Chem Chim Ther, 1985,20(2):111.
11. Warning U, Jakupovic J, Bohlmann F, et al. Scorpiolid, ein neuer sesquiterpenlacton-typ aus Vernonia scorpioides[J]. Liebigs Ann Chem, 1987:467.
12. Jakupovic J, Gage D A, Bohlmann, et al. Sesquiterpene lactones from Vernonia marginata[J]. Phytochemistry, 1986,25(5): 1179.
13. Jakupovic J, Banerjee S, Castro V, et al. Poskeanolide, a secogermacranolide and other sesquiterpene lactones from Vernonia species[J]. Phytochemistry, 1986,25(6):1359.
14. Catalán C A N, Iglesias D I A, Kavka J. Glaucolides and related sesquiterpene lactones from Vernonia chamaedrys[J]. Phytochemistry, 1988,27(1):197.
15. Bardon A, Catalán C A N, Gutierrez A B, et al. Glaucolides and constituents from Vernonia nitiduia[J]. Phytochemistry, 1988,27(8):2691.
16. Catalán C A N, Gutierrez A B, Herz W. Glaucolides and related sesquiterpene lactones from Vernonia incana[J]. Phytochemistry, 1990,29(1):313.
17. Zdero C, Bohlmann F, Mungai G M. A glaucolide-type sesquiterpene lactone from Vernonia galamensis ssp. Nairobensis[J]. Phytochemistry, 1990,29(11):3368.
18. Tsichritzis F, Siems K, Jakupovic J, et al. Sesquiterpene lactones from Vernonia jugalis[J]. Phytochemistry, 1991,30(11):3808.
19. Zdero C, Bohlmann F, Wasshausen D C, et al. Glaucolides from old world Vernonia species[J]. Phytochemistry, 1991,30(12):4025.
20. Perdue R E, Tsichritzis, Jakupovic. Prevernocistifolides from Verninia galamensis[J]. Phytochemistry, 1993,34(4):1075.
21. Bazon J N, Lopes C, Vichnewski W, et al. Cadinanolides and other constituents from Vernonia fruticulosa and Vernonianthura discolor[J]. Phytochemistry, 1997,44(8):1535.
22. Ohigashi H, Jisaka M, Takagaki T, et al. Bitter principle and a related steroid glucoside from Vernonia amygdalina, a possible medicinal plant for wild chimpanzees[J]. Agric Biol Chem, 1991,55(4):1201.
23. 1 from a possible medicinal plant, Vernonia amygdalina, used by wild chimpanzees[J]. Tetrahedron, 1992,48(4):625.
24. Igile G, Oleszek W, Jurzysta M. Vernoniosides D and E, two novel saponins from Vernonia amygdalina[J]. J Nat Prod, 1995,58(9):1438.
25. Jisaka M, Ohigashi H, Takagaki T, et al. Steroid glucosides from Vernonia amygdalina, a possible Chimpanzee medicinal plant[J]. Phytochemisry, 1993,34(2):409.
26. Sanogo R, Germano M P, Tommasi N D, et al. Vernoniosides and an androstane glycoside from Vernonia kotschyana[J]. Phytochemistry, 1998,47(1):73.
27. Ponglux D, Wongseripipatana S, Aimi N, et al. Structures of two mew bitter principles isolated from a Thai medicinal plant, Vernonia externa D. C[J]. Chem Pharm Bull, 1992,40(2):553.
28. Alembert T T, Apollinaire T, Pierre T, et al. Vernoguinosterol and vernoguinoside, trypa-nocidal stigmastane derivatives from Vernonia guineensis (Asteraceae)[J]. Phytochemistry, 2002,59:371.
29. Russell B, Williams A N, Carla S, et al. Cytotoxic sesquiterpene lactones from Vernonia pachyclada from the Madagascar rainforest[J]. J Nat Prod, 2005,68:1371.
30. Awe O, Olajinde O A, Makinde J M, et al. Effects of Allium sativum and Vernonia amygdaline on thrombosis in mice[J]. Phytother Res, 1998,12(1):57.
31. Igile G O, Fafunso M, Fasanmade A, et al. Toxicity of Vernonia amygdalina (Compositeae) leaves, extracts and purified saponins in mice[M]. Olsztyn, Poland, Preceding International European Food Toxin IV, 1994,22-24:394.
32. Germano M P, De pasquale R, Iauk I, et al. Antiulcer activity of Vernonia kotschya-. nasch. bip. [J]. Phytomedicine, 1996,2:229.
33. María C, Martha O, Héctor P, et al. Relaxation of uterine and aortic smooth muscle by Glaucolides D and E from Vernonia liatroi [J]. Biol Pharm Bull, 2003,26(1):112.
34. Ernest B. Discovery of water-soluble anticancer agents from a vegetable found in Benin City, Nigeria[J]. Exp Biol Med (Maywood), 2003,228(3):293.