Vernoguinosterol and vernoguinoside, trypanocidal stigmastane derivatives from Vernonia guineensis (Asteraceae)

Phytochemistry

Volumn 59, Issue 4, 2002, Pages 371-374

  Tchinda, Alembert T ^a   Tsopmo, Apollinaire ^a   Tane, Pierre ^a   Ayafor, Johnson F ^a   Connolly, Joseph D ^b   Sterner, Olov ^c  

^a UNIVERSITY OF DSCHANG   (Cameroon)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c LUND INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

Asteraceae; Stigmastane derivatives; Trypanocidal activity; Vernoguinoside; Vernoguinosterol; Vernonia guineensis

Indexed keywords

ANTITRYPANOSOMAL AGENT; CHOLESTANE DERIVATIVE; SITOSTEROL DERIVATIVE; STIGMASTANE DERIVATIVE; UNCLASSIFIED DRUG; VERNOGUINOSIDE; VERNOGUINOSTEROL; VERNOQUINOSTEROL;

ANIMAL; ANTIPROTOZOAL ACTIVITY; ARTICLE; ASTERACEAE; BARK; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECT; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; IC 50; MEDICINAL PLANT; NONHUMAN; PLANT STEM; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS; TRYPANOSOMA RHODESIENSE; VERNONIA GUINEENSIS; ISOLATION AND PURIFICATION;

ASTERACEAE; VERNONIA;

ANIMALS; ASTERACEAE; DRUG EVALUATION, PRECLINICAL; INHIBITORY CONCENTRATION 50; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PLANT BARK; PLANT STEMS; PLANTS, MEDICINAL; SITOSTEROLS; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI RHODESIENSE;

EID: 0037176730     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9422(01)00448-4     Document Type: Article

References (7)

1. 1 from a possible medicinal plant, Vernonia amygdalina, used by wild chimpanzees
2. Steroid glycosides from Vernonia amygdalina, a possible chimpanzee medicinal plant
3. Venoniosides D and E, two novel saponins from Vernonia amygdalina
4. Structures of two new bitter principles isolated from a Thai medicinal plant Vernonia extensa
5. Vernoniosides and an androstane glycoside from Vernonia kotsehyana
6. Antiplasmodial sesquiterpenoids from the African Reneilmia cincinnata