Effect of ciliary neurotrophic factor on activation of astrocytes in vitro

Neuroscience Bulletin

Volumn 22, Issue 6, 2006, Pages 315-322

  Wu, Yan ^a   Liu, Ren Gang ^a   Zhou, Jie Ping ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Activation; Astrocyte; Cell cycle; Ciliary neurotrophic factor; Proliferation

Indexed keywords

CILIARY NEUTROTROPHIC FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; NEUROTROPHIC FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; BRAIN CORTEX; CELL ACTIVATION; CELL CYCLE; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; FEMALE; FLOW CYTOMETRY; IMAGE ANALYSIS; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT;

EID: 33947180962     PISSN: 16737067     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Wilhelmsson U, Li L, Pekna M, Berthold CH, Blom S, Eliasson C, et al. Absence of glial fibrillary acidic protein and vimentin prevents hypertrophy of astrocytic processes and improves post-traumatic regeneration. J Neurosci 2004, 24: 5016-5021.
2. Albrecht PJ, Dahl JP, Stoltzfus OK, Levenson R, Levison SW. Ciliary neurotrophic factor activates spinal cord astrocytes, stimulating their production and release of fibroblast growth factor-2, to increase motor neuron survival. Exp Neurology 2002, 173: 46-64.
3. McCallister WV, McCallister EL, Dubois B, Trumble TE. Regeneration along intact nerves using nerve growth factor and ciliary neurotrophic factor. J Reconstr Microsurg 2004, 20: 473-481.
4. McCarthy, DeVellis. Oligodendroglial and astroglial cell curltures. J Cell Biol 1980, 85: 890-896.
5. Hudgins SN, Levison SW. Ciliary neurotrophic factor stimulates astroglial hypertrophy in vivo and in vitro. Exp Neurol 1998, 150: 171-182.
6. Levison SW, Hudgins SN, Crawford JL. Ciliary neurotrophic factor stimulates nuclear hypertrophy and increases the GFAP content of cultured astrocytes. Brain Res 1998, 803: 189-193.
7. Song MR, Ghosh A. FGF2-induced chromatin remodeling regulates CNTF-mediated gene expression and astrocyte differentiation. Nat Neurosci 2004, 7: 229-235.
8. Lee MY, Deller T, Kirsch M, Frotscher M, Hofmann HD. Differential regulation of ciliary neurotrophic factor (CNTF) and CNTF receptor alpha expression in astrocytes and neurons of the fascia dentata after entorhinal cortex lesion. J Neurosci 1997, 17: 1137-1146.
9. Kahn MA, Huang CJ, Caruso A. Ciliary neurotrophic factor activates JAK/STAT signal transduction cascade and induces transcriptional expression of glial fibrillary acidic protein in glial cells. J Neurochem 1997, 68: 1413-1423.
10. Shackelford RE, Kaufmann WK, Paules RS. Cell cycle control, checkpoint mechanisms, and genotoxic stress. Environ Health Perspect 1999, 107: 5-24.