Aflatoxin B1 adsorption by clays from water and corn meal

Applied Clay Science

Volumn 36, Issue 1-3, 2007, Pages 197-205

  Jaynes, W F ^a   Zartman, R E ^a   Hudnall, W H ^a  

^a TEXAS TECH UNIVERSITY   (United States)

Author keywords

Activated carbon; Adsorption; Aflatoxins; Clay minerals; ELISA; Feed additives; Montmorillonite; Mycotoxins; n alkylammonium expansion; Sepiolite

Indexed keywords

ACTIVATED CARBON; ADDITIVES; ADSORPTION; AFLATOXINS; AGRICULTURE; FUNGI;

CLAY ADDITIVE; FEED ADDITIVES; MYCOTOXINS; NOVASIL; SEPIOLITE;

CLAY MINERALS;

ACTIVATED CARBON; ADSORPTION; CLAY MINERAL; MONTMORILLONITE;

ANIMALIA; ASPERGILLUS; FUNGI; ZEA MAYS;

EID: 33947177558     PISSN: 01691317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clay.2006.06.012     Document Type: Article

References (39)

1. Afriyie-Gyawu E., Mackie J., Dash B., Wiles M., Taylor J., Huebner H., Tang L., Guan H., Wang J.-S., and Phillips T.D. Long-term toxicological evaluation of Novasil clay in the diet of Sprague-Dawley rats. Food Additives and Contaminants 22 (2005) 259-269
2. AOCS. Aflatoxin standards. Official method Aj 0-88. Sampling and Analysis of Vegetable Oil Source Materials (1999), American Oil Chemists Society
3. 1) in corn, cottonseed, peanuts and peanut butter. Official method Aj 6-95. Sampling and Analysis of Vegetable Oil Source Materials (1999), American Oil Chemists Society
4. 1 in highly contaminated peanut samples using HPLC and ELISA. Food and Agricultural Immunology 14 (2002) 201-208
5. Beaver R.W., and James M.A. Comparison of an ELISA-based screening test with liquid chromatography for the determination of aflatoxins in corn. Journal of the Association of Official Analytical Chemistry 74 (1991) 827-829
6. Bhat R.V., and Vasanthi S. Food safety in food security and food trade. Mycotoxin food safety in developing countries. Focus 10, Brief 3 of 17 (2003), International Food Policy Research Institute. http://www.ifpri.org Available online at
7. Caporael L.R. Ergotism: the Satan loosed in Salem?. Science 192 4234 (1976) 21-26 (2 April 1976)
8. Desheng Q., Fan L., Yanhu Y., and Niya Z. Adsorption of aflatoxin B1 on montmorillonite. Poultry Science 85 (2005) 959-961
9. Diaz D.E., Hagler W.M., Blackwelder J.T., Eve J.A., Hopkins B.A., Anderson K.L., Jones F.T., and Whitlow L.W. Aflatoxin binders II: reduction of aflatoxin M1 in milk by sequestering agents of cows consuming aflatoxin in feed. Mycopathologia 157 (2004) 233-241
10. Edrington T.S., Sarr A.B., Kubena L.F., Harvey R.B., and Phillips T.D. Hydrated sodium calcium aluminosilicate HSCAS, acidic HSCAS, and activated charcoal reduce urinary excretion of aflatoxin AfM1 in turkey poults. Lack of effect by activated charcoal on aflatoxicosis. Toxicology Letters 89 (1996) 115-122
11. FSRIO. A focus on aflatoxin contamination. Food Safety Research Information Office. National Agricultural Library. Agricultural Research Service (2005), United States Department of Agriculture. http://www.nal.usda.gov/fsrio/fsrio@nal.usda.gov Available online at
12. Goldberg B.S., and Angle J.S. Aflatoxin movement in soil. Journal of Environmental Quality 14 (1985) 224-228
13. Grant P.G., and Phillips T.D. Isothermal adsorption of aflatoxin B1 on HSCAS clay. Journal of Agricultural and Food Chemistry 46 (1998) 599-605
14. Hartley R.D., Nesbitt B.F., and O'Kelly J. Toxic metabolites of Aspergillus flavus. Nature 198 (1963) 1056-1058
15. Huwig A., Freimund S., Käppeli O., and Dutler H. Mycotoxin detoxification of animal feed by different adsorbents. Toxicology Letters 122 (2001) 179-188
16. Jaynes W.F., and Boyd S.A. Hydrophobicity of siloxane surfaces in smectites as revealed by aromatic hydrocarbon adsorption from water. Clays and Clay Minerals 39 (1991) 428-436
17. Laing S.S. Dogs Keep Dying: Too Many Owners Remain Unaware of Toxic Dog Food. Republished From Cornell News Service (2006). http://www.foodconsumer.org Available online at .
18. Lagaly G., and Weiss A. The layer charge of smectitic layer silicates. In: Bailey S.W. (Ed). Proceeding of International Clay Conference. Mexico City, 1975 (1976), Applied Publishing, Wilmette, Illinois 157-172
19. Martin A.N. The pet food industry and its questionable practices. Nexus Magazine 10 5 (2003). http://www.nexusmagazine.com Available online at
20. Masimango N., Remacle J., and Ramaut J.L. The role of adsorption in the elimination of aflatoxin B1 from contaminated media. European Journal of Applied Microbiology 6 (1978) 101-105
21. Phillips T.D., Kubena L.F., Harvey R.B., Taylor D.R., and Heidelbaugh N.D. Hydrated sodium calcium aluminosilicate: a high affinity sorbent for aflatoxin. Poultry Science 67 (1988) 243-247
22. Phillips T.D., Sarr A.B., and Grant P.G. Selective chemisorption and detoxification of aflatoxins by phyllosilicate clay. Natural Toxins 3 (1995) 204-213
23. Ramos A.-J., Fink-Gremmels J., and Hernández E. Prevention of toxic effects of mycotoxins by means of nonnutritive adsorbent compounds. Journal of Food Protection 59 (1996) 631-641
24. Ramos A.J., Hernandez E., Pla-Delfina J.M., and Merino M. Intestinal absorption of zearalenone and in vitro study of non-nutritive sorbent materials. International Journal of Pharmacology 128 (1996) 129-137
25. Rao S.B.N., and Chopra R.C. Influence of sodium bentonite and activated charcoal on aflatoxin M1 excretion in milk of goats. Small Ruminant Research 41 (2001) 203-213
26. Rausell-Colom J.A., and Serratosa J.M. Reactions of clays with organic substances. In: Newman A.C.D. (Ed). Chemistry of Clays and Clay Minerals. Monograph vol. 6 (1987), Mineralogical Society, London 409-410
27. Rüehliche G., and Kohler E.E. A simplified procedure for determining layer charge by the n-alkylammonium method. Clay Minerals 16 (1981) 305-307
28. Sargeant K., O'Kelly J., Carnaghan R.B.A., and Allcroft R. The assay of a toxic principle in certain groundnut meals. Veterinary Record 73 (1961) 1219-1223
29. Scheideler S. Effects of various types of aluminosilicates and aflatoxin B1 on aflatoxin toxicity, chick performance, and mineral status. Poultry Science 72 (1993) 282-288
30. Schell T.C., Lindemann M.D., Kornegay E.T., and Blodgett D.J. Effects of feeding aflatoxin-contaminated diets with and without clay to weanling and growing pigs on performance, liver function, and mineral metabolism. Journal of Animal Science 71 (1993) 1209-1218
31. Schell T.C., Lindmann M.D., Kornegay E.T., Blodgett D.J., and Doerr J.A. Effectiveness of different types of clay for reducing the detrimental effects of aflatoxin-contaminated diets on performance and serum profiles of weanling pigs. Journal of Animal Science 71 (1993) 1226-1231
32. Scholthof K.-B.G. One foot in the furrow: linkages between agriculture, plant pathology, and public health. Annual Review of Public Health 24 (2003) 153-174
33. The Texas A&M Aflatoxin Resource. Clinical Effects of Aflatoxicosis (2006). http:////plantpathology.tamu.edu/aflatoxin/effects.htm Available online at
34. van Olphen H., and Fripiat J.J. Data Handbook for Clay Materials and Other Non-metallic Minerals (1979), Pergamon Press, Oxford 23
35. Veldman A. Effect of sorbentia on carry-over of aflatoxin from cow feed to milk. Milchwissenschaft 47 (1992) 777-780
36. Veldman A., Meijs A.C., Borggreve G.J., and Heeres-van der Tol J.J. Carry-over of aflatoxin from cow's food to milk. Animal Production 55 (1992) 163-168
37. Wang J.S., Huang T., Su J., Liang F., Wei Z., Liang Y., Luo H., Kuang S.Y., Qian G.S., Sun G., He X., and Kensler T.W. Hepatocellular carcinoma and aflatoxin exposure in Zhuqing Village, Fusui County, People's Republic of China. Cancer Epidemiology, Biomarkers and Prevention 10 (2001) 143-146
38. Wang J.-S., Luo H., Billam M., Wang Z., Guan H., Tang L., Goldston T., Afriyie-Gyawu E., Lovett C., Griswold J., Brattin B., Taylor R.J., Huebner H.J., and Phillips T.D. Short-term safety evaluation of processed calcium montmorillonite clay (Novasil) in humans. Food Additives and Contaminants 22 (2005) 270-279
39. Yiannikouris A., and Jouany J.-P. Mycotoxins in feeds and their fate in animals: a review. Animal Research 51 (2002) 81-99