Calculating event-triggered average synaptic conductances from the membrane potential

Journal of Neurophysiology

Volumn 97, Issue 3, 2007, Pages 2544-2552

  Pospischil, Martin ^a   Piwkowska, Zuzanna ^a   Rudolph, Michelle ^a   Bal, Thierry ^a   Destexhe, Alain ^a  

^a Unite de Neurosciences Integratives et Computationnelles   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; MATHEMATICAL COMPUTING; NERVE CONDUCTION; PRIORITY JOURNAL; SIMULATION; SPIKE WAVE; SYNAPTIC MEMBRANE; SYNAPTIC POTENTIAL;

ANIMALS; COMPUTER SIMULATION; ELECTRIC CONDUCTIVITY; ELECTRIC STIMULATION; GUINEA PIGS; MEMBRANE POTENTIALS; MODELS, NEUROLOGICAL; NEURONS; OCCIPITAL LOBE; PATCH-CLAMP TECHNIQUES; SYNAPSES;

EID: 33947174634     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.01000.2006     Document Type: Article

References (22)

1. Agüera y Arcas B, Fairhall AL. What causes a neuron to spike? Neural Comput 15: 1789-1807, 2003.
2. Badel L, Gerstner W, Richardson MJE. Dependence of the spike-triggered average voltage on membrane response properties. Neurocomputing 69: 1062-1065, 2006.
3. Borg-Graham L, Monier C, Frégnac Y. Visual input evokes transient and strong shunting inhibition in visual cortical neurons. Nature 393: 369-373, 1998.
4. de Boer F, Kuypers P. Triggered correlation. IEEE Trans Biomed Eng 15: 169-197, 1968.
5. Destexhe A, Rudolph M. Extracting information from the power spectrum of synaptic noise. J Comput Neurosci 17: 327-345, 2004.
6. Destexhe A, Rudolph M, Fellous J-M, Sejnowski TJ. Fluctuating synaptic conductances recreate in-vivo-like activity in neocortical neurons. Neuroscience 107: 13-24, 2001.
7. Destexhe A, Rudolph M, Paré D. The high-conductance state of neocortical neurons in vivo. Nat Rev Neurosci 4: 739-751, 2003.
8. Fourcaud-Trocme N, Hansel D, van Vreeswijk C, Brunel N. How spike generation mechanisms determine the neuronal response to fluctuating inputs. J Neurosci 23: 11628-11640, 2003.
9. Haider B, Duque A, Hasenstaub AR, McCormick DA. Network activity in vivo is generated through a dynamic balance of excitation and inhibition. J Neurosci 26: 4535-4545, 2006.
10. Hines ML, Carnevale NT. The NEURON simulation environment. Neural Comput 9: 1179-1209, 1997.
11. Monier C, Chavane F, Baudot P, Borg-Graham L, Frégnac Y. Orientation and direction selectivity of synaptic inputs in visual cortical neurons: a diversity of combinations produces spike tuning. Neuron 37: 663-680, 2003.
12. Paninski L. The spike-triggered average of the integrate-and-fire cell driven by gaussian white noise. Neural Comput 18: 2592-2616, 2006.
13. Paninski L. The most likely voltage path and large deviations approximations for integrate-and-fire neurons. J Comput Neurosci 21: 71-87, 2006.
14. Paninski L, Pillow J, Simoncelli E. Maximum likelihood estimation of a stochastic integrate-and- fire neural model. Neural Comput 16: 2533-2561, 2004.
15. Pillow J, Simoncelli E. Biases in white noise analysis due to non-Poisson spike generation. Neurocomputing 52: 109-155, 2003.
16. Pinsky PF, Rinzel J. Intrinsic and network rhythmogenesis in a reduced Traub model for CA3 neurons. J Comput Neurosci 1: 39-60, 1994.
17. Robinson HP, Kawai N. Injection of digitally synthesized synaptic conductance transients to measure the integrative properties of neurons. J Neurosci Methods 49: 157-165, 1993.
18. Rudolph M, Pelletier J-G, Par D, Destexhe A. Characterization of synaptic conductances and integrative properties during electrically induced EEG-activated states in neocortical neurons in vivo. J Neurophysiol 94: 2805-2821, 2005.
19. Rudolph M, Piwkowska Z, Badoual M, Bal T, Destexhe A. A method to estimate synaptic conductances from membrane potential fluctuations. J Neurophysiol 91: 2884-2896, 2004.
20. Sharp AA, O'Neil MB, Abbott LF, Marder E. The dynamic clamp: artificial conductances in biological neurons. Trends Neurosci 16: 389-394, 1993.
21. Wehr M, Zador A. Balanced inhibition underlies tuning and sharpens spike timing in auditory cortex. Nature 426: 442-446, 2003.
22. Wilent W, Contreras D. Dynamics of excitation and inhibition underlying stimulus selectivity in rat somatosensory cortex. Nat Neurosci 8: 1364-1370, 2005.