-
1
-
-
0001590389
-
1,3,4-thiadiazoles-III Nucleophilic reactivity of 2-aryl-5-chloro derivatives
-
Alemagna, A., Bachetti, T., and Beltrame, P., 1,3,4-thiadiazoles-III Nucleophilic reactivity of 2-aryl-5-chloro derivatives. Tetrahedron, 24, 3209-3217 (1968).
-
(1968)
Tetrahedron
, vol.24
, pp. 3209-3217
-
-
Alemagna, A.1
Bachetti, T.2
Beltrame, P.3
-
2
-
-
0035042602
-
Type II topoisomerases as targets for quinolone antibacterials: Turning Dr. Jekyll into Mr. Hyde
-
Anderson, V. E. and Osherhoff, N., Type II topoisomerases as targets for quinolone antibacterials: turning Dr. Jekyll into Mr. Hyde. Curr. Pharm. Des., 7, 337-353 (2001).
-
(2001)
Curr. Pharm. Des
, vol.7
, pp. 337-353
-
-
Anderson, V.E.1
Osherhoff, N.2
-
3
-
-
33947157546
-
-
th edition, C. V. Mosby: St. Louis, (1990).
-
th edition, C. V. Mosby: St. Louis, (1990).
-
-
-
-
4
-
-
0022401860
-
Synthesis and structure-activity relationships of novel arylfluoroquinolone antibacterial agents
-
Chu, D. T., Fernandes, P. B., Claiborne, A. K., Pihuleac, E., Nordeen, C. W., Maleczka, R. E., and Pernet, A. G., Synthesis and structure-activity relationships of novel arylfluoroquinolone antibacterial agents. J. Med. Chem., 28, 1558-64 (1985).
-
(1985)
J. Med. Chem
, vol.28
, pp. 1558-1564
-
-
Chu, D.T.1
Fernandes, P.B.2
Claiborne, A.K.3
Pihuleac, E.4
Nordeen, C.W.5
Maleczka, R.E.6
Pernet, A.G.7
-
5
-
-
0035031194
-
Adverse reactions to fluoroquinolones. An overview on mechanistic aspects
-
De Sarro, A. and De Sarro, G., Adverse reactions to fluoroquinolones. An overview on mechanistic aspects. Curr. Med. Chem., 8, 371-374 (2001).
-
(2001)
Curr. Med. Chem
, vol.8
, pp. 371-374
-
-
De Sarro, A.1
De Sarro, G.2
-
6
-
-
0023885198
-
1-Substituted 7-[3-[(ethylamino)methyl]-1- pyrrolidinyl]-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids. New quantitative structure-activity relationships at N1 for the quinolone antibacterials
-
Domagala, J. M., Heifetz, C. L., Hutt, M. P., Mich, T. F., Nichols, J. B., Solomon, M., and Worth, D. F., 1-Substituted 7-[3-[(ethylamino)methyl]-1- pyrrolidinyl]-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids. New quantitative structure-activity relationships at N1 for the quinolone antibacterials. J. Med. Chem., 31, 991-1001 (1988).
-
(1988)
J. Med. Chem
, vol.31
, pp. 991-1001
-
-
Domagala, J.M.1
Heifetz, C.L.2
Hutt, M.P.3
Mich, T.F.4
Nichols, J.B.5
Solomon, M.6
Worth, D.F.7
-
7
-
-
33646584802
-
Structural features of new quinolones and relationship to antibacterial activity against gram-positive bacteria
-
Emami, S., Shafiee, A., and Foroumadi, A., Structural features of new quinolones and relationship to antibacterial activity against gram-positive bacteria. Mini-Rev. Med. Chem., 6, 375-386 (2006).
-
(2006)
Mini-Rev. Med. Chem
, vol.6
, pp. 375-386
-
-
Emami, S.1
Shafiee, A.2
Foroumadi, A.3
-
8
-
-
0034609780
-
Synthesis, antibacterial, and cytotoxic evaluation of certain 7-substituted norfloxacin derivatives
-
Fang, K. C., Chen, Y. L., Sheu, J. Y., Wang, T. C., and Tzeng, C. C., Synthesis, antibacterial, and cytotoxic evaluation of certain 7-substituted norfloxacin derivatives. J. Med. Chem., 43, 3809-3812 (2000).
-
(2000)
J. Med. Chem
, vol.43
, pp. 3809-3812
-
-
Fang, K.C.1
Chen, Y.L.2
Sheu, J.Y.3
Wang, T.C.4
Tzeng, C.C.5
-
9
-
-
24344436793
-
Synthesis and antibacterial activity of N-[2-(5-bromothiophen-2-yl)-2- oxoethyl] and N-[2-(5-bromothiophen-2-yl)-2-oximinoethyl] derivatives of piperazinyl quinolones
-
Foroumadi, A., Emami, S., Mehni, M., Moshafi, M. H., and Shafiee, A., Synthesis and antibacterial activity of N-[2-(5-bromothiophen-2-yl)-2- oxoethyl] and N-[2-(5-bromothiophen-2-yl)-2-oximinoethyl] derivatives of piperazinyl quinolones. Bioorg. Med. Chem. Lett., 20, 4536-4539 (2005a).
-
(2005)
Bioorg. Med. Chem. Lett
, vol.20
, pp. 4536-4539
-
-
Foroumadi, A.1
Emami, S.2
Mehni, M.3
Moshafi, M.H.4
Shafiee, A.5
-
10
-
-
24344458560
-
Synthesis And antibacterial activity of N-(5-benzylthio-1,3,4-thiadiazol-2-yl) and N-(5-benzylsulfonyl-1, 3,4-thiadiazol-2-yl)piperazinyl quinolone derivatives
-
Foroumadi, A., Emami, S., Hassanzadeh, A., Rajaee, M., Sokhanvar, K., Moshafi, M. H., and Shafiee, A., Synthesis And antibacterial activity of N-(5-benzylthio-1,3,4-thiadiazol-2-yl) and N-(5-benzylsulfonyl-1, 3,4-thiadiazol-2-yl)piperazinyl quinolone derivatives. Bioorg. Med. Chem. Lett., 15, 4488-4492 (2005b).
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, pp. 4488-4492
-
-
Foroumadi, A.1
Emami, S.2
Hassanzadeh, A.3
Rajaee, M.4
Sokhanvar, K.5
Moshafi, M.H.6
Shafiee, A.7
-
11
-
-
0028125853
-
Placement of alkyl substituents on the C-7 piperazine ring of fluoroquinolones: Dramatic differential effects on mammalian topoisomerase II and DNA gyrase
-
Gootz, T. D., McGuirk, P. R., Moynihan, M. S., and Haskell, S. L., Placement of alkyl substituents on the C-7 piperazine ring of fluoroquinolones: dramatic differential effects on mammalian topoisomerase II and DNA gyrase. Antimicrob. Agents. Chemother., 38, 130-133 (1994).
-
(1994)
Antimicrob. Agents. Chemother
, vol.38
, pp. 130-133
-
-
Gootz, T.D.1
McGuirk, P.R.2
Moynihan, M.S.3
Haskell, S.L.4
-
12
-
-
0033231154
-
Synthesis and anti-HIV activity of arylpiperazinyl fluoroquinolones: A new class of anti-HIV agents
-
Hagihara, M., Kashiwase, H., Katsube, T., Kimura, T., Komai, T., Momota, K., Ohmine, T., Nishigaki, T., Kimura, S., and Shimada, K., Synthesis and anti-HIV activity of arylpiperazinyl fluoroquinolones: a new class of anti-HIV agents. Bioorg. Med. Chem. Lett., 9, 3063-3068 (1999).
-
(1999)
Bioorg. Med. Chem. Lett
, vol.9
, pp. 3063-3068
-
-
Hagihara, M.1
Kashiwase, H.2
Katsube, T.3
Kimura, T.4
Komai, T.5
Momota, K.6
Ohmine, T.7
Nishigaki, T.8
Kimura, S.9
Shimada, K.10
-
13
-
-
0034022016
-
Synthesis, antibacterial, antifungal and anti-HIV activities of norfloxacin mannich bases
-
Pandeya, S. N., Sriram, D., Nath, G., and De Clercq, E., Synthesis, antibacterial, antifungal and anti-HIV activities of norfloxacin mannich bases. Eur. J. Med. Chem., 35, 249-255 (2000).
-
(2000)
Eur. J. Med. Chem
, vol.35
, pp. 249-255
-
-
Pandeya, S.N.1
Sriram, D.2
Nath, G.3
De Clercq, E.4
-
14
-
-
0030498049
-
-
Shafiee, A. and Foroumadi, A., Synthesis of arylsulfonyl-1,3,4- thiadiazoles. J. Heterocycl. Chem., 33, 1611-1614 (1996).
-
Shafiee, A. and Foroumadi, A., Synthesis of arylsulfonyl-1,3,4- thiadiazoles. J. Heterocycl. Chem., 33, 1611-1614 (1996).
-
-
-
-
15
-
-
0024546107
-
Mechanism of inhibition of DNA gyrase by quinolone antibacterials: A cooperative drug-DNA binding model
-
Shen, L. L., Mitscher, L. A., Sharma, P. N., O'Donnell, T. J., Chu, D. W., Cooper, C. S., Rosen, T., and Pernet, A. G., Mechanism of inhibition of DNA gyrase by quinolone antibacterials: a cooperative drug-DNA binding model. Biochemistry, 28, 3886-3894 (1989).
-
(1989)
Biochemistry
, vol.28
, pp. 3886-3894
-
-
Shen, L.L.1
Mitscher, L.A.2
Sharma, P.N.3
O'Donnell, T.J.4
Chu, D.W.5
Cooper, C.S.6
Rosen, T.7
Pernet, A.G.8
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