Intestinal thrombotic microangiopathy induced by FK506 in rats

Bone Marrow Transplantation

Volumn 39, Issue 6, 2007, Pages 367-372

  Fujino, M ^a   Kim, Y ^b,c   Ito, M ^a,b  

^a JAPANESE RED CROSS NAGOYA FIRST HOSPITAL   (Japan)

^b NAGOYA UNIVERSITY HOSPITAL   (Japan)

^c The Catholic University of Korea   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

TACROLIMUS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD VESSEL WALL; CELL ADHESION; CELL SWELLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; ELECTRON MICROSCOPY; ENDOTHELIUM CELL; ENZYME IMMUNOASSAY; GRAFT VERSUS HOST REACTION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INTESTINAL BLEEDING; INTESTINE ISCHEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; THROMBOCYTE AGGREGATION; THROMBOTIC THROMBOCYTOPENIC PURPURA; THROMBUS; WISTAR RAT;

ANIMALS; APOPTOSIS; CAPILLARIES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTOCYTOCHEMISTRY; IMMUNOSUPPRESSIVE AGENTS; INTESTINAL MUCOSA; MALE; PERIPHERAL VASCULAR DISEASES; RATS; RATS, WISTAR; TACROLIMUS; THROMBOSIS;

EID: 33947130309     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/sj.bmt.1705588     Document Type: Article

References (33)

1. Nash RA, Pineiro LA, Storb R, Deeg HJ, Fitzsimmons WE, Furlog T et al. FK506 in combination with methotrexate for the prevention of graft-versus-host disease after bone marrow transplantation from matched unrelated donors. Blood 1996; 88: 3634-3641.
2. Uberti JP, Silver SM, Adams PT, Jacobson P, Scalzo A, Ratanatharathorn V. Tacrolimus and methotrexate for the prophylaxis of acute graft-versus host disease in allogeneic bone marrow transplantation in patients with hematologic malignancies. Bone Marrow Transplant 1997; 19: 1233-1238.
3. Holler E, Kolb HJ, Hiller E, Mraz W, Lehmacher W, Gleixner B et al. Microangiopathy in patients on cyclosporine prophylaxis who developed acute graft-versus-host disease after HLA-identical bone marrow transplantation. Blood 1989; 73: 2018-2024.
4. Ichihashi T, Naoe T, Yoshida H, Kiyoi H, Fukutani H, Kubo K et al. Haemolytic uremic syndrome during FK506 therapy. Lancet 1992; 340: 60-61.
5. Gharpure VS, Devine SM, Holland HK, Geller RB, O'Toole K, Wingard JR. Thrombotic thrombocytopenic purpura associated with FK506 following bone marrow transplantation. Bone Marrow Transplant 1995; 16: 715-718.
6. Paquatte RL, Tran L, Landaw EM. Thrombotic microangiopathy following allogeneic bone marrow transplantation is associated with intensive graft-versus-host disease prophylaxis. Bone Marrow Transplant 1998; 22: 351-357.
7. Nalesnik MA, Todo S, Murase N, Gryzam S, Lee PH, Makowka L et al. Toxicology of FK-506 in the lewis rat. Transplant Proc 1987; 19 (Suppl 6): 89-92.
8. Kumano K, Wang G, Endo T, Kuwao S. FK506-induced nephrotoxicity in rats. Transplant Proc 1991; 23: 512-515.
9. Yamada K, Sugisaki Y, Akimoto M, Yamanaka N. Short-term FK 506-induced morphological changes in rat kidneys. Transplant Proc 1991; 23: 3130-3132.
10. Japanese FK 506 study group. Clinicopathological evaluation of kidney transplants in patients given a fixed dose of FK 506. Transplant Proc 1991; 23: 3111-3115.
11. Japanese FK 506 study group. Morphological characteristics of renal allografts showing renal dysfunction under FK 506 therapy: Is graft biopsy available to reveal the morphological findings corresponding with FK 506 nephropathy? Transplant Proc 1993; 25: 624-627.
12. Randhawa PS, Shapiro R, Jordan ML, Starzl TE, Demetris AJ. The histopathological changes associated with allograft rejection and drug toxicity in renal transplant recipients maintained on FK506. Am J Surg Pathol 1993; 17: 60-68.
13. Randhawa PS, Tsamandas AC, Magnone M, Jordan M, Shapiro R, Starzl TE et al. Microvascular changes in renal allografts associated with FK506 (Tacrolimus) therapy. Am J Surg Pathol 1996; 20: 306-312.
14. Trimarchi HM, Truong LD, Brennan S, Gonzalez JM, Suki WN. FK506-associated thrombotic microangiopathy. Transplantation 1999; 67: 539-544.
15. Sniecinski IJ, O'Donnell MR. Hemolytic complications of hemopoietic cell transplantation. In: Thomas ED, Blume KG, Forman SJ (eds). Hematopoietic Cell Transplantation. Blackwell Science: Malden, 1999, pp 674-684.
16. Nishida T, Hamaguchi M, Hirabayashi N, Haneda M, Terakura S, Atsuta Y et al. Intestinal thrombotic microangiopathy after allogeneic bone marrow transplantation: A clinical imitator of acute enteric graft-versus-host disease. Bone Marrow Transplant 2004; 33: 1143-1150.
17. Narimatsu H, Kami M, Hara S, Matsumura T, Miyakoshi S, Kusumi E et al. Intestinal thrombotic microangiopathy following reduced-intensity umbilical cord blood transplantation. Bone Marrow Transplant 2005; 36: 517-523.
18. Pettitt AR, Clark RE. Thrombotic microangiopathy following bone marrow transplantation. Bone Marrow Transplant 1994; 14: 495-504.
19. Dumler JS, Beschorner WE, Farmer ER, DiGennaro KA, Saral R, Santos GW1. Endothelial-cell injury in cutaneous acute graft-versus-host disease. Am J Pathol 1989; 135: 1097-1103.
20. Sale GE, Shulman HM, Hackman RC. Pathology of hematopoietic cell transplantation. In: Thomas ED, Blume KG, Forman SJ (eds). Hematopoietic Cell Transplantation. Blackwell Science: Malden, 2004, pp 286-299.
21. Bombi JA, Nadal A, Carreras E, Ramirez J, Munoz J, Rozman C et al. Assessment of histopathologic changes in the colonic biopsy in acute graft-versus-host disease. Am J Clin Pathol 1995; 103: 690-695.
22. McDonald GB, Shulman HM, Sullivan KM, Spencer GD. Intestinal and hepatic complications of human bone marrow transplantation. Gastroenterology 1986; 990: 770-784.
23. Kornacki S, Hansen FC, Lazenby A. Graft-versus-host-like colitis associated with malignant thymoma. Am J Surg Pathol 1995; 19: 224-228.
24. Lee FD. Importance of apoptosis in the histopathology of drug related lesions in the large intestine. J Clin Pathol 1993; 46: 118-122.
25. Cummings MC, Winterford CM, Walker NI. Apoptosis. Am J Surg Pathol 1997; 21: 88-101.
26. Frisch SM, Francis H. Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 1994; 124: 619-626.
27. Thorning D, Howard JD. Epithelial denudement in the gastrointestinal tracts of two bone marrow transplant recipients. Human Pathol 1986; 17: 560-566.
28. Murayama T, Nakagawa T, Matsushita K, Matozaki S, Yasutake K, Kizaki T et al. Hemorrhagic colitis with unusual colonoscopy features, complicated with chronic graft-versus-host disease after allogeneic bone marrow transplantation. Bone Marrow Transplant 1995; 15: 141-143.
29. Fox RJ, Vogelsang GB, Beschorner WE. Denuded bowel after recovery from graft-versus-host disease. Transplantation 1996; 62: 1681-1684.
30. Selby DM, Rudzki JR, Bayever ES, Chandra RS. Vasculopathy of small muscular arteries in pediatric patients after bone marrow transplantation. Hum Pathol 1999; 30: 734-740.
31. Backman L, Nicar M, Levy M, Distant D, Eisenstein C, Renard T et al. FK506 trough levels in whole blood and plasma in liver transplant recipients. Transplantation 1994; 57: 519-525.
32. Machida M, Takahara S, Ishibashi M, Hayashi M, Sekihara T, Yamanaka H. Effect of temperature and hematocrit on plasma concentration of FK506. Transplant Proc 1991; 23: 2753-2754.
33. Nagase K, Iwasaki K, Nozaki K, Noda K. Distribution and protein binding of FK506, a potent immunosuppressive macrolide lactone, in human blood and its uptake by erythrocytes. J Pharm Pharmacol 1994; 46: 113-117.