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Volumn 9, Issue 5, 2007, Pages 841-844

Three-component, one-pot sequential synthesis of N-Aryl, N′-alkyl barbiturates

Author keywords

[No Author keywords available]

Indexed keywords

1,4-DIOXANE; BARBITURIC ACID DERIVATIVE; DIOXANE; DIOXANE DERIVATIVE; ESTER; MALONIC ACID; MALONIC ACID DERIVATIVE; SODIUM HYDROXIDE; UNCLASSIFIED DRUG;

EID: 33947129709     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol063074+     Document Type: Article
Times cited : (29)

References (24)
  • 2
    • 84890597202 scopus 로고    scopus 로고
    • For an overview of multicomponent reactions, see: a, Zhu, J, Bienaymé, H, Eds, Wiley-VCH: Weinheim, Germany
    • For an overview of multicomponent reactions, see: (a) Multicomponent Reactions; Zhu, J., Bienaymé, H., Eds.; Wiley-VCH: Weinheim, Germany, 2005.
    • (2005) Multicomponent Reactions
  • 3
    • 27444432929 scopus 로고    scopus 로고
    • Multicomponent reactions. Marek, I., Ed.; Tetrahedron Symposium-in-Print No. 114. Tetrahedron 2005, 61, 11309-11519.
    • (b) Multicomponent reactions. Marek, I., Ed.; Tetrahedron Symposium-in-Print No. 114. Tetrahedron 2005, 61, 11309-11519.
  • 14
    • 33947101896 scopus 로고    scopus 로고
    • Weygand/Hilgetag Preparative Organic Chemistry; Wiley: New York, 1972; p 493.
    • Weygand/Hilgetag Preparative Organic Chemistry; Wiley: New York, 1972; p 493.
  • 15
    • 22544467759 scopus 로고    scopus 로고
    • For a recent improvement of this reaction by microwave irradiation, see
    • For a recent improvement of this reaction by microwave irradiation, see: Devi, I.; Bhuyan, P. J. Tetrahedron Lett. 2005, 46, 5727-5729.
    • (2005) Tetrahedron Lett , vol.46 , pp. 5727-5729
    • Devi, I.1    Bhuyan, P.J.2
  • 18
    • 22944470620 scopus 로고
    • For a review on carbodiimide chemistry, see
    • For a review on carbodiimide chemistry, see: Williams, A.; Ibrahim, I. T. Chem. Rev. 1981, 81, 589-636.
    • (1981) Chem. Rev , vol.81 , pp. 589-636
    • Williams, A.1    Ibrahim, I.T.2
  • 19
    • 0002658479 scopus 로고
    • For a pioneering work on the synthesis of barbituric acids from malonic acids and carbodiimides, see
    • For a pioneering work on the synthesis of barbituric acids from malonic acids and carbodiimides, see: Bose, K. A.; Garratt, S.; Pelosi, J. J. J. Org. Chem. 1963, 28, 730-733.
    • (1963) J. Org. Chem , vol.28 , pp. 730-733
    • Bose, K.A.1    Garratt, S.2    Pelosi, J.J.3
  • 24
    • 33947141257 scopus 로고    scopus 로고
    • Increasing the temperature during the last step resulted in the formation of complex mixtures
    • Increasing the temperature during the last step resulted in the formation of complex mixtures.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.