Oxidative stress is the primary event: Effects of ethanol consumption in brain

Indian Journal of Clinical Biochemistry

Volumn 22, Issue 1, 2007, Pages 99-104

  Das, Subir Kumar ^a   Hiran, K R ^a   Mukherjee, Sukhes ^a   Vasudevan, D M ^a  

^a AMRITA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Brain; Ethanol; Glutathione; Oxidative stress; Phosphatase; Transferase

Indexed keywords

ALCOHOL; ALKALINE PHOSPHATASE; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASE; CATALASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; THIOBARBITURIC ACID;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRAIN; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; HISTOPATHOLOGY; MALE; NONHUMAN; OXIDATIVE STRESS; RAT;

RATTUS;

EID: 33947124492     PISSN: 09701915     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02912890     Document Type: Article

References (35)

1. Calabrese V, Scapagnini G, Latteri S, Colombrita C, Ravagna A, Catalano C, Pennisi G, Calvani M, Butterfield DA. Long-term ethanol administration enhances age-dependent modulation of redox state in different brain regions in the rat: protection by acetyl carnitine. Int J Tissue React 2002; 24(3): 97-104.
2. Diamond I, Gordon AS. Cellular and molecular neuroscience of alcoholism. Physiol Rev 1997; 77: 1-20.
3. Gupta YK, Gupta M, Kohli K. Neuroprotective role of melatonin in oxidative stress vulnerable brain. Ind J Physiol Pharmacol 2003; 47(4): 373-86.
4. Skaper SD, Floreani M, Ceccon M, Facci L, Giusti P. Excitotoxicity, oxidative stress, and the neuroprotective potential of melatonin. Ann NY Acad Sci 1999; 890: 107-18.
5. Gilman SC, Bonner MJ, Pellmar TC. Effect of oxidative stress on excitatory amino acid release by cerebral cortical synaptosomes. Free Radic Biol Med 1993; 15(6): 671-5.
6. Gilgun-Sherki Y, Rosenbaum Z, Melamed E, Offen D. Antioxidant therapy in acute central nervous system injury: current state. Pharmacol Rev 2002; 54(2): 271-84.
7. Gonthier B, Signorini-Allibe N, Soubeyran A, Eysseric H, Lamarche F, Barret L. Ethanol can modify the effects of certain free radical-generating systems on astrocytes. Alcohol Clin Exp Res 2004; 28(4): 526-34.
8. Das SK, Vasudevan DM. Effect of lecithin in the treatment of ethanol mediated free radical induced hepatotoxicity. Ind J Clin Biochem 2006; 21(1): 62-69.
9. Lowry OH, Rosenbourgh NJ, Farr AL, Randall RJ. Protein measurement with folin phenol reagent. J Biol Chem 1951; 193: 265-75.
10. Linhardt K, Walter K. Phosphatase. In: Bergmeyer HU, editor. Methods of Enzymatic Analysis. NY: Academic Press, 1963: 799.
11. Bergmeyer HU, Bernt E. Glutamate oxaloacetate transaminase; Glutamate pyruvate transaminase. In: Bergmeyer HU, editor. Methods of Enzymatic Analysis. NY: Academic Press Inc, 1963: 837-53.
12. Roe JH, Kuether CA. The determination of ascorbic acid in whole blood and urine through the 2,4-dinitrophenyl hydrazine derivative of dehydro ascorbic acid. J Biol Chem 1943; 147: 399-401.
13. Ellman GL. The sulphydryl groups. Arch. Biochem. Biophys. 1959; 32: 70-77.
14. Sinnhuber RO, Yu TC. Characterization of the red pigment formed in the thiobarbituric acid determination of oxidative rancidity. Food Res 1958; 23: 626-30.
15. rd ed. Florida: Academic Press Inc, 1983: 258-65.
16. Habig WH, Pabst MJ, Jakoby WB. Glutathione S-transferase, the first enzymatic step in mercapturic acid formation. J Biol Chem 1974; 249: 7130-9.
17. Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterisation of erythrocyte glutathione peroxides. J Lab Clin Med 1967; 70: 158-9.
18. Marklund S, Marklund G. Involvement of superoxide radical in the auto oxidation pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 1974; 47: 469-74.
19. Das SK, Vasudevan DM. Effect of ethanol on liver antioxidant defense systems: a dose dependent study. Ind J Clin Biochem 2005; 20(1): 79-83.
20. Harper C, Matsumoto I. Ethanol and brain damage. Curr Opin pharmacol 2005; 5: 73-8.
21. Kril JJ, Halliday GM, Svoboda MD, Cartwright H. The cerebral cortex is damaged in chronic alcoholics. Neuroscience. 1997; 79: 983-98.
22. Cohen S. Phosphatases, In: Lajtha A, editor, Handbook of Neurochemistry. NY: Plenum Press, 1970: 87-131.
23. Sedman G L, Austin L, Langford CJ. Protein turnover in brain during the development of alcohol dependence. Neurosci. Lett 1982; 28: 93-9.
24. 3H leucine incorporation into brain and liver protein. I. Acute intoxication and vitamin deficiency in rats. J Stud Alcohol 1976; 37: 1178-87.
25. Dasgupta S, Ghosh S. Nicotine induced alterations in brain acid and alkaline phosphatase activities. Ind J Physiol Allied Sci 1993; 47: 200-6.
26. Anderson PJ, Song SK. Acid phosphatase in the nervous system. J Neuropathol Neurol 1962; 21: 263-83.
27. Matcovis B, Varga SI, Szaluo L, Witsas H. The effect of diabetes on the activities of the peroxide metabolic enzymes. Hor Metb Res 1982; 14: 77-9.
28. Svensson L, Wu C, Johannessen K, Engel JA. Effect of ethanol on ascorbate release in the nucleus accumbens and striatum of freely moving rats. Alcohol 1992; 9(6): 535-40.
29. Carney JM, Strake-Reed PE, Oliver CN, Landum RW, Chang MS, Wu JF, Floyd RA. Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity and loss in temporal and spatial memory by chronic administration of the spin trapping compound N-tert-buty-alfa-pheynitrone. PNAS 1991; 88: 3633-6.
30. Nistico G, Cirilol HR, Fiskin K, Iannone M, Martino A, Rotilio G. NGF restores decrease in catalase activity and increases superoxide dismutase and glutathione peroxidase activity in the brain of aged rats. Free Radic Biol Med 1992; 12: 177-81.
31. Scapagnini G, Ravagna A, Bella R, Colombrita C, Pennisi G, Calvani M, Alkon D, Calabrese V. Long-term ethanol administration enhances age-dependent modulation of redox state in brain and peripheral organs of rat: protection by acetyl carnitine. Int J Tissue React 2002; 24(3): 89-96.
32. Hemachand T, Gopalakrishnan B, Salunke DM, Totey SM, Shaha C. Sperm plasma-membrane-associated glutathione S-transferases as gamete recognition molecules. J Cell Sci 2002; 115: 2053-65.
33. Davenport CJ, Ali SF, Miller FJ, Lipe GW, Morgan KT, Bonnefoi MS. Effect of methyl bromide on regional brain glutathione, glutathione-S-transferases, monoamines, and amino acids in F344 rats. Toxicol Appl Pharmacol 1992; 112(1): 120-7.
34. Yu BP. Cellular defense against damage from reactive oxygen species. Physiol Rev 1994; 74: 139-62.
35. Aydin S, Ozaras R, Uzun H, Belce A, Uslu E, Tahan V, Altug T, Dumen E, Senturk H. N-acetylcysteine reduced the effect of ethanol on antioxidant system in rat plasma and brain tissue. Tohoku J Exp Med 2002; 198(2): 71-7.