Crystal Structure of N-acetyl-γ-glutamyl-phosphate Reductase from Mycobacterium tuberculosis in Complex with NADP+

Journal of Molecular Biology

Volumn 367, Issue 5, 2007, Pages 1357-1369

  Cherney, Leonid T ^a   Cherney, Maia M ^a   Garen, Craig R ^a   Niu, Chunying ^a   Moradian, Fatemeh ^b   James, Michael N G ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b TARBIAT MODARES UNIVERSITY   (Iran)

Author keywords

catalytic mechanism; Mycobacterium tuberculosis; NADP+ binding site; oxidoreductase; X ray crystallography

Indexed keywords

ARGININE; BACTERIAL ENZYME; CARBOXYL GROUP; CYSTEINE; GLUTAMIC ACID; GUANIDINE; HISTIDINE; LEUCINE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXIDOREDUCTASE; PHOSPHATE; PROTEIN AGPR; PROTEIN SUBUNIT; PROTON; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME STABILITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; ENZYME SUBUNIT; HYDROGEN BOND; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTON TRANSPORT; STEREOSPECIFICITY;

MYCOBACTERIUM TUBERCULOSIS;

EID: 33947119090     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.01.033     Document Type: Article

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