Pharmacokinetics of gatifloxacin after a single oral dose in healthy young adult subjects and adult patients with chronic bronchitis, with a comparison of drug concentrations obtained by bronchoscopic microsampling and bronchoalveolar lavage

Clinical Therapeutics

Volumn 29, Issue 1, 2007, Pages 123-130

  Kikuchi, Junko ^a   Yamazaki, Koichi ^a   Kikuchi, Eiki ^a   Ishizaka, Akitoshi ^b   Nishimura, Masaharu ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

bronchoscopic microsampling; bronchoscopy; chronic bronchitis; epithelial lining fluid; gatifloxacin; pharmacokinetics

Indexed keywords

GATIFLOXACIN;

ADULT; AGED; ANALYTIC METHOD; AREA UNDER THE CURVE; ARTICLE; BRONCHOSCOPIC MICROSAMPLING; BRONCHOSCOPY; CHRONIC BRONCHITIS; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; HUMAN; LUNG ALVEOLUS EPITHELIUM; LUNG LAVAGE; SINGLE DRUG DOSE; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; ADULT; AGED; ANTI-INFECTIVE AGENTS; AREA UNDER CURVE; BRONCHITIS, CHRONIC; BRONCHOALVEOLAR LAVAGE; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHOSCOPY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLUOROQUINOLONES; HUMANS; MIDDLE AGED; SPECIMEN HANDLING;

EID: 33947111488     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/j.clinthera.2007.01.005     Document Type: Article

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