Overexpression of laminin-5 γ2 chain in clear cell carcinoma of the ovary

Virchows Archiv

Volumn 450, Issue 3, 2007, Pages 273-278

  Kato, Noriko ^a   Sasou, Shun Ichi ^b   Teshima, Shin Ichi ^c   Motoyama, Tei Ichi ^a  

^a YAMAGATA UNIVERSITY   (Japan)

^b Yamagata Prefectural Central Hospital   (Japan)

^c Department of Pathology   (Japan)

Author keywords

Borderline clear cell tumor; Clear cell carcinoma; Laminin 5 2 chain; Migration; Ovary

Indexed keywords

ALPHA3 INTEGRIN; ANTIBODY; KALININ; LAMININ 5 GAMMA 2; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CELL INTERACTION; CELL MIGRATION; CLEAR CELL CARCINOMA; CLINICAL ARTICLE; CYTOPLASM; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; OVARY CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE; STROMA;

ADENOCARCINOMA, CLEAR CELL; ANTIBODIES, BLOCKING; CELL LINE, TUMOR; CELL MOVEMENT; CYTOPLASM; FEMALE; HUMANS; INTEGRIN ALPHA3; LAMININ; NEOPLASM INVASIVENESS; NEOPLASM STAGING; OVARIAN NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 33847750345     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-006-0354-7     Document Type: Article

References (22)

1. Benedet JL, Bender H, Jones HW III, Ngan HY, Pecorelli S (2000) FIGO staging classifications and clinical practice guidelines in the management of gynecologic cancers. FIGO committee on gynecologic oncology. Int J Gynaecol Obstet 70:209-262
2. Carter WG, Ryan MC, Gahr PJ (1991) Epigrin, a new cell adhesion ligand for integrinα3β1 in epithelial basement membranes. Cell 65:599-610
3. Fukushima Y, Ohnishi T, Arita N, Hayakawa T, Sekiguchi K (1998) Integrinα3β1-mediated interaction with laminin-5 stimulates adhesion, migration and invasion of malignant glioma cells. Int J Cancer 76:63-72
4. Giannelli G, Falk-Marzillier J, Schiraldi O, Steler-Stevenson WG, Quaranta V (1997) Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5. Science 277:225-228
5. Kariya Y, Tsubota Y, Hirosaki T, Mizushima H, Puzon-McLaughlin W, Takada Y, Miyazaki K (2003) Differential regulation of cellular adhesion and migration by recombinant laminin-5 forms with partial deletion or mutation within the G3 domain of α3 chain. J Cell Biochem 88:506-520
6. Kariya Y, Miyazaki K (2004) The basement membrane protein laminin-5 acts as a soluble cell motility factor. Exp Cell Res 297:508-520
7. Kiyoshima K, Oda Y, Kinukawa N, Naito S, Tsuneyoshi M (2005) Overexpression of laminin-5 γ2 chain and its prognostic significance in urothelial carcinoma of urinary bladder: association with expression of cyclooxygenase 2, epidermal growth factor, and human epidermal growth factor 2. Hum Pathol 36:522-530
8. Koshikawa N, Moriyama K, Takamura H, Mizushima H, Nagashima Y, Yanoma S, Miyazaki K (1999) Overexpression of laminin gamma2 chain monomer in invading gastric cancel cells. Cancer Res 59:5596-5601
9. Koshikawa N, Giannelli G, Cirulli V, Miyazaki K, Quaranta V (2000) Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5. J Cell Biol 148:615-624
10. Maata M, Butzow R, Luostarinen J, Petajaniemi N, Pihlajaniemi T, Salo S, Miyazaki K, Autio-Harmainen H, Virtanen I (2005) Differential expression of laminin isoforms in ovarian epithelial carcinomas suggesting different origin and providing tools for differential diagnosis. J Histochem Cytochem 53:1293-1300
11. McCarthy JB, Furcht LT (1984) Laminin and fibronection promote the haptotactic migration of B16 mouse melanoma cells in vitro. J Cell Biol 98:1474-1480
12. Mikami Y, Hata S, Melamed J, Moriya T, Manabe T (1999) Basement membrane material in ovarian clear cell carcinoma: correlation with growth pattern and nuclear grade. Int J Gynecol Pathol 18:52-57
13. Miyazaki K (2006) Laminin-5 (laminin-332): unique biological activity and role in tumor growth and invasion. Cancer Sci 97:91-98
14. Nguyen BP, Gil SG, Carter WG (2000) Deposition of laminin 5 by keratinocytes regulates integrin adhesion and signaling. J Biol Chem 275:31896-31907
15. Ogawa T, Tsubota Y, Maeda M, Kariya Y, Miyazaki K (2004) Regulation of biological activity of laminin-5 by proteolytic processing of γ2 chain. J Cell Biochem 92:701-714
16. Ono Y, Nakanishi Y, Ino Y, Niki T, Yamada T, Yoshimura K, Saikawa M, Nakajima T, Hirohashi S (1999) Clinicopathologic significance of laminin-5 gamma2 chain expression in squamous cell carcinoma of the tongue: immunohistochemical analysis of 67 cases. Cancer 85:2315-2321
17. Prat J (2004) Clear cell tumors. In: Prat J (ed) Pathology of the ovary. Saunders, Philadelphia, pp 153-162
18. Pyke C, Salo S, Ralfkiaer E, Romer J, Dano K, Tryggvason K (1995) Laminin-5 is a marker of invading cancer cells in some human carcinomas and is coexpressed with the receptor for urokinase plasminogen activator in budding cancer cells in colon adenocarcinomas. Cancer Res 55:4132-4139
19. Rousselle P, Lunstrum GP, Keene DR, Burgeson RE (1991) Kalinin: an epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments. J Cell Biol 114:567-576
20. Scully RE, Young RH, Clement PB (1998) Clear cell tumors. In: Rosai J (ed) Tumor of the ovary, maldeveloped gonads, fallopian tube, and broad ligament. Atlas of tumor pathology, 3rd series, fascicle 23. AFIP, Washington, DC, pp 141-151
21. Soini Y, Maatta M, Salo S, Tryggvason K, Autio-Harmainen H (1996) Expression of the lamininγ2 chain in pancreatic adenocarcinoma. J Pathol 180:290-294
22. Wong WSF, Wong YF, Ng YTA, Huang PD, Chew EC, Ho TH, Chang MZA (1990) Establishment and characterization of a new human cell line derived from ovarian clear cell carcinoma. Gynecol Oncol 38:37-45