Calcium regulation of troponin and its role in the dynamics of contraction and relaxation

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 292, Issue 3, 2007, Pages

  Stehle, Robert ^a   Iorga, Bogdan ^b   Pfitzer, Gabriele ^b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BEPRIDIL; CALCIUM; CALCIUM ION; TROPOMYOSIN; TROPONIN; TROPONIN C; TROPONIN I;

DRUG MECHANISM; EDITORIAL; MUSCLE CONTRACTION; MUSCLE FIBRIL; MUSCLE ISOMETRIC CONTRACTION; MUSCLE RELAXATION; PRIORITY JOURNAL;

CALCIUM; KINETICS; MUSCLE CONTRACTION; MUSCLE RELAXATION; TROPONIN; TROPONIN C; TROPONIN I;

EID: 33847747433     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00841.2006     Document Type: Editorial

References (36)

1. Bremel RD, Weber A. Cooperation within actin filament in vertebrate skeletal muscle. Nat New Biol 238: 97-101, 1972.
2. 2+ on cross-bridge turnover kinetics in skinned single rabbit psoas fibers: implications for regulation of muscle contraction. Proc Natl Acad Sci USA 85: 3265-3269, 1988.
3. Brenner B, Chalovich JM. Kinetics of thin filament activation probed by fluorescence of N-{[2-(Iodoacetoxy)ethyl]-N-methyl}amino-7-nitrobenz- 2-oxa-1, 3-diazole-labeled troponin I incorporated into skinned fibers of rabbit psoas muscle: implications for regulation of muscle contraction. Biophys J 77: 2692-2708, 1999.
4. 2+ binding and functional properties of chicken skeletal muscle troponin. J Biol Chem 269: 14988-14994, 1994.
5. Colomo F, Nencini S, Piroddi N, Poggesi C, Tesi C. Calcium dependence of the apparent rate of force generation in single striated muscle myofibrils activated by rapid solution changes. Adv Exp Med Biol 453: 373-381, 1998.
6. de Tombe PP, Belus A, Piroddi N, Scellini B, Walker JS, Martin AF, Tesi C, Poggesi C. Myofilament calcium sensitivity does not affect cross-bridge activation-relaxation kinetics. Am J Physiol Regul Integr Comp Physiol 292: R1129-R1136, 2007.
7. 2+ to the regulatory site of troponin from cardiac muscle. J Biol Chem 272: 19229-19235, 1997.
8. Engel PL, Kobayashi T, Biesiadecki B, Davis J, Tikunova S, Wu S, Solaro RJ. Identification of a region of troponin I important in signaling cross-bridge dependent activation of cardiac myofilaments. J Biol Chem 282: 183-193, 2007.
9. Gordon AM, Homsher E, Regnier M. Regulation of contraction in striated muscle. Physiol Rev 80: 853-924, 2000.
10. 2+-specific regulatory sites of troponin C. J Biol Chem 269: 8919-8923, 1994.
11. Krüger M, Pfitzer G, Stehle R. Expression and purification of human cardiac troponin subunits and their functional incorporation into isolated cardiac mouse myofibrils. J Chromatogr B Analyt Technol Biomed Life Sci 786: 287-296, 2003.
12. Krüger M, Zittrich S, Redwood C, Blaudeck N, James J, Robbins J, Pfitzer G, Stehle R. Effects of the mutation R145G in human cardiac troponin I on the kinetics of the contraction-relaxation cycle in isolated cardiac myofibrils. J Physiol 564: 347-357, 2005.
13. Li MX, Wang X, Lindhout DA, Buscemi N, Van Eyk JE, Sykes BD. Phosphorylation and mutation of human cardiac troponin I deferentially destabilize the interaction of the functional regions of troponin I with troponin C. Biochemistry 42: 14460-14468, 2003.
14. Li MX, Wang X, Sykes BD. Structural based insights into the role of troponin in cardiac muscle pathophysiology. J Muscle Res Cell Motil 25: 559-579, 2004.
15. Li Y, Love ML, Putkey JA, Cohen C. Bepridil opens the regulatory N-terminal lobe of cardiac troponin C. Proc Natl Acad Sci USA 97: 5140-5145, 2000.
16. Lin X, Dotson DG, Putkey JA. Covalent binding of peptides to the N-terminal hydrophobic region of cardiac troponin C has limited effects on function. J Biol Chem 271: 244-249, 1996.
17. Lionne C, Iorga B, Candau R, Travers F. Why choose myofibrils to study muscle myosin ATPase? J Muscle Res Cell Motil 24: 139-148, 2003.
18. Luo Y, Davis JP, Smillie LB, Rall JA. Determinants of relaxation rate in rabbit skinned skeletal muscle fibres. J Physiol 545: 887-901, 2002.
19. Martin AF, Ball K, Gao LZ, Kumar P, Solaro RJ. Identification and functional significance of troponin I isoforms in neonatal rat heart myofibrils. Circ Res 69: 1244-1252, 1991.
20. McKillop DF, Geeves MA. Regulation of the interaction between actin and myosin subfragment 1: evidence for three states of the thin filament. Biophys J 65: 693-701, 1993.
21. 2+ regulation in developing rabbit cardiac muscle. Biochem Biophys Res Commun 267: 912-917, 2000.
22. Narolska NA, Piroddi N, Belus A, Boontje NM, Scellini B, Deppermann S, Zaremba R, Musters RJ, dos Remedios C, Jaquet K, Foster DB, Murphy AM, van Eyk JE, Tesi C, Poggesi C, van der Velden J, Stienen GJ. Impaired diastolic function after exchange of endogenous troponin I with C-terminal truncated troponin I in human cardiac muscle. Circ Res 99: 1012-1020, 2006.
23. 2+ activation and relaxation in rat and guinea pig skinned trabeculae. Circ Res 83: 179-186, 1998.
24. 2+ affinity. Biochemistry 31: 6545-6553, 1992.
25. Piroddi N, Tesi C, Pellegrino MA, Tobacman LS, Homsher E, Poggesi C. Contractile effects of the exchange of cardiac troponin for fast skeletal troponin in rabbit psoas single myofibrils. J Physiol 552: 917-931, 2003.
26. Piroddi N, Belus A, Scellini B, Tesi C, Giunti G, Cerbai E, Mugelli A, Poggesi C. Tension generation and relaxation in single myofibrils from human atrial and ventricular myocardium. Pflügers Arch. In press.
27. Poggesi C, Tesi C, Stehle R. Sarcomeric determinants of striated muscle relaxation kinetics. Pflügers Arch 449: 505-517, 2005.
28. Siedner S, Krüger M, Schroeter M, Metzler D, Roell W, Fleischmann BK, Hescheler J, Pfitzer G, Stehle R. Developmental changes in contractility and sarcomeric proteins from the early embryonic to the adult stage in the mouse heart. J Physiol 548: 493-505, 2003.
29. 2+-changes. Biophys J 83: 2152-2161, 2002.
30. Stehle R, Krüger M, Scherer P, Brixius K, Schwinger RH, Pfitzer G. Isometric force kinetics upon rapid activation and relaxation of mouse, guinea pig and human heart muscle studied on the subcellular myofibrillar level. Basic Res Cardiol 97, Suppl 1: I127-I135, 2002.
31. Stehle R, Krüger M, Pfitzer G. Does cross-bridge activation determine the time course of myofibrillar relaxation? Adv Exp Med Biol 538: 469-479, 2003.
32. Stehle R, Solzin J, Iorga B, Gomez D, Blaudeck N, Pfitzer G. Mechanical properties of sarcomeres during cardiac myofibrillar relaxation: stretch-induced cross-bridge detachment contributes to early diastolic filling. J Muscle Res Cell Motil 27: 423-434, 2006.
33. 2+ reduction in single myofibrils from skeletal muscle. Biophys J 83: 2142-2151, 2002.
34. Van Eyk JE, Strauss JD, Hodges RS, Ruegg JC. A synthetic peptide mimics troponin I function in the calcium-dependent regulation of muscle contraction. FEBS Lett 323: 223-228, 1993.
35. Vibert P, Craig R, Lehman W. Steric-model for activation of muscle thin filaments. J Mol Biol 266: 8-14, 1997.
36. 2+ sensitizers. Biophys J 76: 2166-2176, 1999.