A microvolumetric β blood counter for pharmacokinetic PET studies in small animals

IEEE Transactions on Nuclear Science

Volumn 54, Issue 1, 2007, Pages 173-180

  Convert, L ^b   Morin Brassard, G ^c   Cadorette, J ^b   Rouleau, D ^b   Croteau, E ^b   Archambault, M ^b   Fontaine, R ^a,c   Lecomte, R ^a,b  

^a IEEE

^b UNIVERSITY OF SHERBROOKE   (Canada)

^c UNIVERSITÉ DE SHERBROOKE   (Canada)

Author keywords

Beta ( ) detector; Blood sampling; Pharmacokinetic modeling; Small animal PET

Indexed keywords

BLOOD; COMPUTER SIMULATION; PHARMACOKINETICS; PHOTODIODES; RADIOTHERAPY; REAL TIME SYSTEMS;

BLOOD SAMPLING; BLOOD TRACER CONCENTRATION; PHARMACOKINETIC MODELING;

POSITRON EMISSION TOMOGRAPHY;

EID: 33847742544     PISSN: 00189499     EISSN: None     Source Type: Journal    
DOI: 10.1109/TNS.2006.889166     Document Type: Article

References (20)

1. B. Y. Croft, "Animal Models for Imaging," Disease Markers, vol. 18, no. 5-6, pp. 365-374, 2002.
2. P. G. Anderson, S. B. Digerness, J. L. Sklar, and P. J. Boor, "Use of the isolated perfused heart for evaluation of cardiac toxicity," Toxicol. Pathol., vol. 18, no. 4, pp. 497-510, 1990.
3. C. Depre, "Isolated working heart: description of models relevant to radioisotopic and pharmacological assessments," Nucl. Med. Biol., vol. 25, no. 8, pp. 711-713, 1998.
4. S. R. Cherry and S.S. Gambhir, "Use of positron emission tomography in animal research," ILAR Journal, vol. 42, no. 3, pp. 219-232, 2001.
5. F. Pain and P. Lanièce, New Advances in in vivo small animal imaging, NuPECC Report, 2001, IPN/Orsay, 7p.
6. A. F. Chatziioannou, "Molecular imaging of small animals with dedicated PET tomographs," Eur. J. Nucl. Med. Mol. Imag., vol. 29, no. 1, pp. 98-114, 2002.
7. O. Muzik, R. S. Beanlands, G. D. Hutchins, T. J. Mangner, N. Nguyen, and M. Schwaiger, "Validation of nitrogen-13-ammonia tracer kinetic model for quantification of myocardial blood flow using PET," J. Nucl. Med., vol. 34, no. 1, pp. 83-91, 1993.
8. K. H. Diehl, R. Hull, D. Morton, R. Pfister, Y. Rabemampianina, D. Smith, J. M. Vidal, and C. van de Vorstenbosch, "A good practice guide to the administration of substances and removal of blood, including routes and volumes," J. Appl. Toxicol., vol. 21, no. 1, pp. 15-23, 2001.
9. A. Villanueva Jr, S. P. Stoll, D. J. Schlyer, S. Shokouhi, P. Vaska, C. L. Woody, A. Kriplani, and N. Volkow, "Spatial resolution of a noninvasive measurement of the arterial and venous input function using a wrist monitor," in Proc. IEEE Nuclear Science Symp. Conf. Rec., 2003, vol. 4, pp. 2232-2236.
10. M. Itoh, H. Watabe, M. Miyake, S. Hagisawa, T. Fujiwara, R. Iwata, T. Ido, and T. Nakamura, "Noninvasive determination of arterial input of 150 tracers, using a dual cutaneous B-detector set above the radial artery," in Quantification of Brain Function Using PET. New York: Academic, 1996, ch. 14, pp. 67-71.
11. F. Pain, P. Lanièce, R. Mastrippolito, P. Gervais, P. Hantraye, and L. Besret, "Arterial Input Function Measurement Without Blood Sampling Using a β-Microprobe in Rats," J. Nucl. Med., vol. 45, no. 9, pp. 1577-1582, 2004.
12. N. Kudomi, E. Choi, S. Yamamoto, H. Watabe, K. M. Kim, M. Shidahara, M. Ogawa, N. Teramoto, E. Sakamoto, and H. Iida, "Development of a GSO detector assembly for a continuous blood sampling system," IEEE Trans. Nucl. Sci., vol. 50, no. 1, pp. 70-73, Feb. 2003.
13. D. Lapointe, J. Cadorette, S. Rodrigue, D. Rouleau, and R. Lecomte, "A microvolumetric blood counter/sampler for metabolic PET studies in small animals," IEEE Trans. Nucl. Sci., vol. 45, no. 4, pp. 2195-2199, Aug. 1998.
14. L. Eriksson, S. Holte, C. Bohm, M. Kesselberg, and B. Hovander, "Automated blood sampling systems for positron emission tomography," IEEE Trans. Nucl. Sci., vol. 35, no. 1, pp. 703-707, Feb. 1988.
15. G. F. Knoll, Radiation Detection and Measurement, 3rd ed. New York: Wiley, 2000, pp. 96, 120-124.
16. L. Eriksson and I. Kanno, "Blood sampling devices and measurements," Med. Prog. Technol., vol. 17, no. 3-4, pp. 249-257, 1991.
17. J. R. Votaw and S. D. Shulman, "Performance evaluation of the pico-count flow-through detector for use in cerebral blood flow PET studies," J. Nucl. Med., vol. 39, no. 3, pp. 509-515, 1998.
18. H. Iida, I. Kanno, S. Miura, M. Murakami, K. Takahashi, and K. Uemura, "Error analysis of a quantitative cerebral blood flow measurement using H2(15)O autoradiography and positron emission tomography, with respect to the dispersion of the input function," J. Cereb. Blood Flow Metab., vol. 6, no. 5, pp. 536-545, 1986.
19. M. M. Graham and B. L. Lewellen, "High-speed automated discrete blood sampling for positron emission tomography," J. Nucl. Med., vol. 34, no. 8, pp. 1357-1360, 1993.
20. E. Croteau, F. Bénard, C. Dubuc, M. Archambault, M. Bentourkia, J. Cadorette, and R. Lecomte, "Correction of metabolite and spillover for myocardial blood flow with ammonia in small animal PET," Mol. Imag. Biol., vol. 6, no. 2, p. 94, 2004.