Effects of epidural anaesthesia on surgical stress-induced immunosuppression during upper abdominal surgery

British Journal of Anaesthesia

Volumn 98, Issue 2, 2007, Pages 196-203

  Kawasaki, T ^a   Ogata, M ^a   Kawasaki, C ^a   Okamoto, K ^b   Sata, T ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Anaesthesia, general; Anaesthetic techniques, epidural; Immune response, suppression; Surgery, GI

Indexed keywords

BROTIZOLAM; CD14 ANTIGEN; FENTANYL; HLA DR ANTIGEN; HYDROCORTISONE; INTERLEUKIN 10; ISOFLURANE; LIPOPOLYSACCHARIDE; MEPIVACAINE; NITROUS OXIDE; PROPOFOL; TUMOR NECROSIS FACTOR ALPHA; VECURONIUM; ANESTHETIC AGENT;

ABDOMINAL SURGERY; ADULT; ANTIGEN EXPRESSION; ARTICLE; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); CONTINUOUS INFUSION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DERMATOME; EPIDURAL ANESTHESIA; EX VIVO STUDY; FEMALE; GENERAL ANESTHESIA; HOST RESISTANCE; HUMAN; IMMUNE DEFICIENCY; INFORMED CONSENT; INNATE IMMUNITY; MALE; MONOCYTE; NEUTROPHIL; PARTIAL GASTRECTOMY; PERIOPERATIVE PERIOD; PHAGOCYTOSIS; POSTOPERATIVE PAIN; PREOPERATIVE PERIOD; PRIORITY JOURNAL; RESPIRATORY BURST; STOMACH CANCER; SURGICAL STRESS; BIOSYNTHESIS; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; GASTRECTOMY; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; MIDDLE AGED; RANDOMIZED CONTROLLED TRIAL; STOMACH TUMOR; STRESS;

ANESTHESIA, EPIDURAL; ANESTHESIA, GENERAL; ANESTHETICS, COMBINED; ANTIGENS, CD14; FEMALE; GASTRECTOMY; HLA-DR ANTIGENS; HUMANS; IMMUNE TOLERANCE; INTERLEUKIN-10; LIPOPOLYSACCHARIDES; MALE; MIDDLE AGED; MONOCYTES; NEUTROPHILS; PHAGOCYTOSIS; RESPIRATORY BURST; STOMACH NEOPLASMS; STRESS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33847720629     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/ael334     Document Type: Article

References (28)

1. Duignan JP, Collins PB, Johnson AH, Bouchier-Hayes D. The association of impaired neutrophil chemotaxis with postoperative surgical sepsis. Br J Surg 1986; 73: 238-40
2. Utoh J, Yamamoto T, Utsunomiya T, et al. Effect of surgery on neutrophil functions, superoxide and leukotriene production. Br J Surg 1988; 75: 682-5
3. Ogata M, Okamoto K, Kohriyama K, et al. A role of interleukin 10 on hyporesponsiveness of endotoxin during surgery. Crit Care Med 2000; 28: 3166-70
4. Kawasaki T, Ogata M, Kawasaki C, et al. Surgical stress induces endotoxin hyporesponsiveness and an early decrease of monocyte mCD14 and HLA-DR expression during surgery. Anesth Analg 2001; 92: 1322-6
5. Wakefield CH, Carey PD, Foulds S, et al. Changes in major histocompatibility complex class II expression in monocytes and T cells of patients developing infection after surgery. Br J Surg 1993; 80: 205-9
6. Tonnensen E, Wahlgreen C. Influence of extradural and general anaesthesia on natural killer cell activity and lymphocyte subpopulations in patients undergoing hysterectomy. Br J Anaesth 1988; 60: 500-7
7. Tonnesen E, Huttel MS, Christensen NJ, Schmitz O. Natural killer cell activity in patients undergoing upper abdominal surgery: Relationship to the endocrine stress response. Acta Anaesthesiol Scand 1984; 28 654-60
8. Norman JG, Fink GW. The effect of epidural anesthesia on the neuroendocrine response to major surgical stress: A randomized prospective trial. Am Surg 1997; 63: 75-80
9. McCarthy L, Wetzel M, Sliker JK, Eisenstein TK, Rogers TJ. Opioids, opioid receptors, and the immune response. Drug Alcohol Depend 2001; 62: 111-123
10. Ogata M, Matsumoto T, Koga K, et al. An antagonist of platelet-activating factor suppresses endotoxin-induced tumor necrosis factor and mortality in mice pretreated with carrageenan. Infect Immun 1993; 61: 699-704
11. Ziegler-Heitbrock HW, Ulevitch RJ. CD14: Cell surface receptor differentiation marker. Immunol Today 1993; 14: 121-5
12. Redmond HP, Watson RW, Houghton T. et al. Immune function in patients undergoing open vs laparoscopic cholecystectomy. Arch Surg 1994; 129: 1240-6
13. De Rossi L, Gott K, Horn N, et al. Xenon preserves neutrophil and monocyte function in human whole blood. Can J Anaesth 2002; 49 942-5
14. Ertel W, Kremer JP, Kenny J, et al. Downregulation of proinflammatory cytokine release in whole blood from septic patients. Blood 1995; 85: 1341-7
15. Astiz M, Saha D, Lustbader D, et al. Monocyte response to bacterial toxins, expression of cell surface receptors, and release of anti-inflammatory cytokines during sepsis. J Lab Clin Med 1996; 128: 594-600
16. Majetschak M, Flach R, Kreuzfelder E, et al. The extent of traumatic damage determines a graded depression of the endotoxin responsiveness of peripheral blood mononuclear cells from patients with blunt injuries. Crit Care Med 1999; 27: 313-8
17. Ziegenfuss T, Wanner GA, Grass C, et al. Mixed agonistic-antagonistic cytokine response in whole blood from patients undergoing abdominal aortic aneurysm repair. Intensive Care Med 1999; 25: 279-87
18. Schiff DE, Kline L, Soldau K, et al. Phagocytosis of gram-negative bacteria by a unique CD14-dependent mechanism. J Leukocyte Biol 1997; 62: 786-94
19. Hole A, Unsgaard G. The effect of epidural and general anaesthesia on lymphocyte functions during and after major orthopaedic surgery. Acta Anaesthesiol Scand 1983; 27: 135-41
20. Hole A, Unsgaard G, Breivik H. Monocyte functions are depressed during and after surgery under general anaesthesia but not under epidural anaesthesia. Acta Anaesthesiol Scand 1982; 26: 301-7
21. Loick HM, Schmidt C, Van Aken H, et al. High thoracic epidural anesthesia, but not clonidine, attenuates the perioperative stress response via sympatholysis and reduces the release of troponin T in patients undergoing coronary artery bypass grafting. Anesth Analg 1999; 88: 701-9
22. Segawa H, Mori K, Kasai K, et al. The role of the phrenic nerves in stress response in upper abdominal surgery. Anesth Analg 1996; 82: 1215-24
23. van der Poll T, Barber AE, Coyle SM, Lowry SF. Hypercortisolemia increases plasma interleukin-10 concentrations during human endotoxemia: a clinical research center study. J Clin Endocrinol Metab 1996; 81: 3604-6
24. Steer JH, Vuong Q, Joyce DA. Suppression of human monocyte tumor necrosis factor-alpha release by glucocorticoid therapy: Relationship to systemic monocytopenia and cortisol suppression. Br J Clin Pharmacol 1997; 43: 383-9
25. Ogata M, Yanagida K, Takenaka I, et al. The effect of anesthesia and partial hepatectomy on plasma rennin and aldosterone: Comparison between nitrous oxide-enflurane anesthesia and epidural nitrous oxide anesthesia. Masui 1988; 37: 163-8
26. Ogata M, Takara H, Shimozawa K, et al. The mechanism of aldosterone secretion during partial gastrectomy. Masui 1986; 35: 924-8
27. Dahanukar SA, Thatte UM, Deshmukh UD, et al. The influence of surgical stress on the psychoneuro-endocrine-immune axis. J Postgrad Med 1996; 42: 12-4
28. Klava A, Windsor ACJ, Farmery SM, et al. Interleukin-10: A role in the development of postoperative immunosuppression. Arch Surg 1997; 132: 425-9