Endometriosis may be generated by mimicking the ontogenetic development of the female genital tract

Fertility and Sterility

Volumn 87, Issue 3, 2007, Pages 651-656

  Gaetje, Regine ^a   Holtrich, Uwe ^a   Engels, Knut ^a   Kissler, Stefan ^a   Rody, Achim ^a   Karn, Thomas ^a   Kaufmann, Manfred ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

endometrium; endosalpingiosis; PAX8 paired box gene 8; peritoneum; WNT wingless type MMTV integration site family

Indexed keywords

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOMETRIOSIS; EXPERIMENTAL STUDY; FEMALE; FEMALE GENITAL SYSTEM; GENE; GENE EXPRESSION; HOUSEKEEPING GENE; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; METAPLASIA; NUCLEOTIDE SEQUENCE; ONTOGENY; PAX8 GENE; PERITONEUM; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TREATMENT INDICATION; WNT4 GENE; WNT5A GENE; WNT7A GENE;

ENDOMETRIOSIS; FEMALE; GENITALIA, FEMALE; HUMANS; IN SITU HYBRIDIZATION; PAIRED BOX TRANSCRIPTION FACTORS; PERITONEUM; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; WNT PROTEINS;

EID: 33847696187     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2006.07.1533     Document Type: Article

References (18)

1. Goldman M.B., and Cramer D.W. The epidemiology of endometriosis. In: Brosens I., and Donnet J. (Eds). Current concepts in endometriosis (1990), Alan R. Liss, New York 15-31
2. Battista G., Vercellini P., Fedele L., Colombo A., and Candiiani M. Mild endometriosis and infertility: a clinical review of epidemiologic data, diagnostic pitfalls, and classification limits. Obstet Gynecol Surv 46 (1991) 374-379
3. Hemmings R., Rivard M., Olive D.L., Poliquin-Fleury J., Gagne D., Hugo P., et al. Evaluation of risk factors associated with endometriosis. Fertil Steril 81 (2004) 1513-1521
4. Gaetje R., Kotzian S., Herrmann G., Baumann R., and Starzinski-Powitz A. Invasiveness of endometriotic cells in vitro. Lancet 346 (1995) 1463-1464
5. Sampson J.A. Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into peritoneal cavity. Obstet Gynecol 14 (1927) 422-469
6. Lauchlan S.C. The secondary muellerian system. Obstet Gynecol Surv 27 (1972) 133-146
7. Vainio S., Heikkilä M., Kispert A., Chin N., and McMahon A.P. Female development in mammals is regulated by wnt-4 signalling. Nature 397 (1999) 405-409
8. Parr B.A., and McMahon A.P. Sexually dimorphic development of the mammalian reproductive tract requires WNT-7A. Nature 395 (1998) 707-710
9. Mericsky M., Kitajewski J., and Sassoon D. WNT-5A is required for proper epithelial-mesenchymal interactions in the uterus. Development 131 (2004) 2061-2072
10. Carta L., and Sassoon D. WNT-7A is a suppressor of cell death in the female reproductive tract and is required for postnatal and estrogen-mediated growth. Biol Reprod 71 (2004) 444-454
11. Miller C., and Sassoon D.A. WNT-7A maintains appropriate uterine patterning during the development of the mouse female reproductive tract. Development 125 (1998) 3201-3211
12. Holtrich U., Wolf G., Brauninger A., Karn T., Bohme B., Rubsamen-Waigmann H., et al. Induction and down-regulation of PLK, a human serine/threonine kinase expressed in proliferating cells and tumors. Proc Natl Acad Sci USA 91 (1994) 1736-1740
13. Ahr A., Holtrich U., Solbach C., Scharl A., Strebhardt K., Karn T., et al. Molecular classification of breast cancer patients by gene expression profiling. J Pathol 195 (2001) 312-320
14. Basyuk E., Bertrand E., and Journot L. Alkaline fixation drastically improves the signal of in situ hybridization. Nucleic Acids Res 28 (2000) E46
15. Balasch J., Creus M., Fabregues F., Carmona F., Ordi J., Martinez-Roman S., et al. Visible and non-visible endometriosis at laparoscopy in fertile and infertile women and in patients with chronic pelvic pain: a prospective study. Hum Reprod 11 (1996) 387-391
16. Nisolle M., Paindaveine B., Bourdon A., Berliere M., Casanas-Roux F., and Donnez J. Histologic study of peritoneal endometriosis in infertile women. Fertil Steril 53 (1990) 984-988
17. Bouchard M., Souabni A., Mandler M., Neubuser A., and Busslinger M. Nephric lineage specification by Pax2 and Pax8. Genes Dev 16 (2002) 2958-2970
18. Balasch J., Creus M., Fabregues F., Carmona F., Ordi J., Martinez-Roman S., et al. Visible and non-visible endometriosis at laparoscopy in fertile and infertile women and in patients with chronic pelvic pain: a prospective study. Hum Reprod 11 (1996) 387-391