Increased lymphocyte deoxyribonucleic acid damage in patients with cardiac syndrome X

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 617, Issue 1-2, 2007, Pages 8-15

  Gur, Mustafa ^a   Yildiz, Ali ^a   Demirbag, Recep ^a   Yilmaz, Remzi ^a   Koçyigit, Abdurrahim ^a   Celik, Hakim ^a   Aksoy, Nurten ^a  

^a HARRAN UNIVERSITY   (Turkey)

Author keywords

Cardiac syndrome X; Comet assay; DNA damage; Inflammation; Oxidative stress; Total antioxidant status

Indexed keywords

ANTIOXIDANT; C REACTIVE PROTEIN; CELL DNA; PROTEIN HSCRP; UNCLASSIFIED DRUG;

ANGIOCARDIOGRAPHY; ANTIOXIDANT ACTIVITY; ARTICLE; CARDIAC SYNDROME X; CLINICAL ARTICLE; COMET ASSAY; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; DNA DAMAGE; DRUG BLOOD LEVEL; HEART DISEASE; HUMAN; HUMAN CELL; INFLAMMATION; MULTIPLE LINEAR REGRESSION ANALYSIS; OXIDATIVE STRESS; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; ST SEGMENT DEPRESSION; TREADMILL EXERCISE;

ANTIOXIDANTS; BLOOD GLUCOSE; C-REACTIVE PROTEIN; CASE-CONTROL STUDIES; COMET ASSAY; CORONARY ANGIOGRAPHY; DNA DAMAGE; EXERCISE TEST; FASTING; FEMALE; HUMANS; HYDROGEN PEROXIDE; LYMPHOCYTES; MALE; MICROVASCULAR ANGINA; MIDDLE AGED; OXIDATION-REDUCTION; OXIDATIVE STRESS;

EID: 33847693573     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2006.08.012     Document Type: Article

References (31)

1. Cannon R.O., and Epstein S.E. Microvascular angina as a cause of chest pain with angiographically normal coronary arteries. Am. J. Cardiol. 61 (1988) 1338-1343
2. Crea F., and Lanza G.A. Angina pectoris and normal coronary arteries: cardiac syndrome X. Heart 90 (2004) 457-463
3. Dominguez-Rodriguez A., Garcia-Gonzalez M., and Abreu-Gonzalez P. Cardiac syndrome X: diagnosis, pathogenesis and management. Am. J. Cardiovasc. Drugs 4 (2004) 423-424
4. Vane J.R., Anggard E.E., and Botting R.M. Regulatory functions of the vascular endothelium. N. Engl. J. Med. 323 (1990) 27-36
5. Satake O., Kajinami K., Ishikawa Y., Ueda T., Tsugawa H., Kanemitsu S., et al. Myocardial glucose metabolism assessed by positron emission tomography and the histopathologic findings of microvessels in syndrome X. Circ. J. 68 (2004) 220-226
6. Cannon III R.O., Leon M.B., Watson R.M., Rosing D.R., and Epstein S.E. Chest pain and 'normal' coronary arteries-role of small coronary arteries. Am. J. Cardiol. 55 (1985) 50B-60B
7. Panting J.R., Gatehouse P.D., Yang G.Z., Grothues F., Firmin D.N., Collins P., and Pennell D.J. Abnormal subendocardial perfusion in cardiac syndrome X detected by cardiovascular magnetic resonance imaging. N. Engl. J. Med. 346 (2002) 1948-1953
8. Lanza G.A., Sestito A., Cammarota G., Grillo R.C., Vecile E., Cianci R., Speziale D., Dobrina A., Maseri A., and Crea F. Assessment of systemic inflammation and infective pathogen burden in patients with cardiac syndrome X. Am. J. Cardiol. 94 (2004) 40-44
9. On Y.K., Park R., Hyon M.S., Kim S.K., and Kwon Y.J. Are low total serum antioxidant status and elevated levels of C-reactive protein and monocyte chemotactic protein-1 associated with cardiac syndrome X?. Circ. J. 69 (2005) 1212-1217
10. Lekakis J.P., Papamichael C.M., Vemmos C.N., Voutsas A.A., Stamatelopoulos S.F., and Moulopoulos S.D. Peripheral vascular endothelial dysfunction in patients with angina pectoris and normal coronary arteriograms. J. Am. Coll. Cardiol. 31 (1998) 541-546
11. Asbury E.A., Creed F., and Collins P. Distinct psychosocial differences between women with coronary heart disease and cardiac syndrome X. Eur. Heart J. 25 (2004) 1695-1701
12. Rice Evans C., and Miller N.J. Total antioxidant status in plasma and body fluids. Methods Enzymol. 234 (1994) 279-293
13. Halliwell B., and Aruoma O. DNA damage by oxygen-derived species: its mechanism and measurement in mammalian systems. FEBS Lett. 281 (1991) 9-19
14. Ames B.N. Endogenous DNA damage as related to cancer and ageing. Free Radic. Res. Commun. 7 (1989) 121-128
15. Dong M., Wang C., Deen W.M., and Dedon P.C. Absence of 2′-deoxyoxanosine and presence of abasic sites in DNA exposed to nitric oxide at controlled physiological concentrations. Chem. Res. Toxicol. 16 (2003) 1044-1055
16. Botto N., Rizza A., Colombo M.G., Mazzone A.M., Manfredi S., Masetti S., Clerico A., Biagini A., and Andreassi M.G. Evidence for DNA damage in patients with coronary artery disease. Mutat. Res. 493 (2001) 23-30
17. Botto N., Masetti S., Petrozzi L., Vassalle C., Manfredi S., Biagini A., and Andreassi M.G. Elevated levels of oxidative DNA damage in patients with coronary artery disease. Coron. Artery Dis. 13 (2002) 269-274
18. Andreassi M.G., Botto N., Rizza A., Colombo M.G., Palmieri C., Berti S., Manfredi S., Masetti S., Clerico A., and Biagini A. Deoxyribonucleic acid damage in human lymphocytes after percutaneous transluminal coronary angioplasty. J. Am. Coll. Cardiol. 40 (2002) 862-868
19. Andreassi M.G., Botto N., Cocci F., Battaglia D., Antonioli E., Masetti S., Manfredi S., Colombo M.G., Biagini A., and Clerico A. Methylenetetrahydrofolate reductase gene C677T polymorphism, homocysteine, Vitamin B12, and DNA damage in coronary artery disease. Hum. Genet. 112 (2003) 171-177
20. Ross R. Atherosclerosis an inflammatory disease. N. Engl. J. Med. 340 (1999) 115-126
21. Demirbag R., Yilmaz R., and Kocyigit A. Relationship between DNA damage, total antioxidant capacity and coronary artery disease. Mutat. Res. 570 (2005) 197-203
22. Andreassi M.G. Coronary atherosclerosis and somatic mutations: an overview of the contributive factors for oxidative DNA damage. Mutat. Res. 543 (2003) 67-86
23. Singh P.N., McCoy M.T., Tice R.R., and Schneider E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 175 (1988) 184-191
24. Collins A.R. The comet assay for DNA damage and repair: principles, applications and limitations. Mol. Biotechnol. 26 (2004) 249-261
25. Collins A., Dusinska M., Franklin M., Somorovska M., Petrovska H., Duthie S., Fillion L., Panayiotidis M., Raslova K., and Vaughan N. Comet assay in human biomonitoring studies: reliability, validation, and applications. Environ. Mol. Mutagen. 30 (1997) 139-146
26. Erel O. A novel automated method to measure total antioxidant response against potent free radical reactions. Clin. Biochem. 37 (2004) 112-119
27. Demirbag R., Yilmaz R., Gur M., Kocyigit A., Celik H., Guzel S., and Selek S. Lymphocyte DNA damage in patients with acute coronary syndrome and its relationship with severity of acute coronary syndrome. Mutat. Res. 578 (2005) 298-307
28. Martinet W., Knaapen M.W., De Meyer G.R., Herman A.G., and Kockx M.M. Elevated levels of oxidative DNA damage and DNA repair enzymes in human atherosclerotic plaques. Circulation 106 (2002) 927-932
29. Lee J., Lee M., Kim J.K., Song K., Choi Y.S., and Cheong S.S. Carvedilol reduces plasma 8-hydroxy-2-deoxyguanosine in mild to moderate hypertension a pilot study. Hypertension 45 (2005) 986-990
30. Schottenfeld D., and Beebe-Dimmer J. Chronic inflammation: a common and important factor in the pathogenesis of neoplasia. CA Cancer J. Clin. 56 2 (2006) 69-83
31. Wiseman H., and Halliwell B. Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer. Biochem. J. 313 (1996) 17-29