Design, synthesis and biological evaluation of new oxazines with potential antiparasitic activity

Tetrahedron Letters

Volumn 48, Issue 14, 2007, Pages 2505-2507

  Gamenara, Daniela ^a   Heinzen, Horacio ^a   Moyna, Patrick ^a  

^a UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

Author keywords

[No Author keywords available]

Indexed keywords

ALKADIENE; ARTEMISININ; BENZNIDAZOLE; CARVONE; CHLOROQUINE; NITROSO DERIVATIVE; OXAZINE DERIVATIVE; PENTAMIDINE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; TERPENE DERIVATIVE;

ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; DIELS ALDER REACTION; DRUG ACTIVITY; DRUG DESIGN; DRUG SYNTHESIS; IN VITRO STUDY; NONHUMAN; PLASMODIUM FALCIPARUM; TRYPANOSOMA CRUZI; TRYPANOSOMA RHODESIENSE;

ALNUS; PLASMODIUM FALCIPARUM; TRYPANOSOMA BRUCEI RHODESIENSE; TRYPANOSOMA CRUZI;

EID: 33847684380     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2007.02.032     Document Type: Article

References (18)

1. Tracy J.W., and Webster L.T. Fármacos usados en la quimioterapia de infecciones causadas por protozoarios. Las Bases Farmacológicas de la Terapéutica Vol. II (1996), Goodman & Gilman Ed.; Ed. Interamericana, México DF 1025-1047
2. Enserink M. Science 287 (2000) 1956-1958
3. Woerdenbag H.J., Pras N., Van Uden W., Wallaart T.E., Beekmann A.C., and Lugt C.B. Pharm. World Sci. 16 (1994) 169-180
4. Phillipson J.D., and O'Neill M.J. Biological Active Natural Products (1987), Oxford Science, Oxford, England
5. Meshnick S.R., Taylor T.E., and Kamchonwongpaisan S. Microbiol. Rev. 60 (1996) 301-315
6. Laurent S.A.-L., Robert A., and Meunier B. Angew. Chem., Int. Ed. 44 (2005) 2060-2063
7. Posner G.H., and Oh C.H. J. Am. Chem. Soc. 114 (1992) 8328-8329
8. Posner G.H., Oh C.H., Wang D., Gerena L., Milhous W.K., Meshnick S.R., and Asawamahasakda W. J. Med. Chem. 37 (1994)
9. Posner G.H., and O'Neill P.M. Acc. Chem. Res. 37 (2004) 397-404
10. Pauling L. The Nature of the Chemical Bond. 3rd ed. (1960), Cornell, Univ. Press., New York
11. Ren H., Grady S., Gamenara D., Heinzen H., Moyna P., Croft S.L., Kendrick H., Yardley V., and Moyna G. Bioorg. Med. Chem. Lett. 11 (2001) 1851-1854
12. Corey E.J., and Burke H.J. J. Am. Chem. Soc. 78 (1956) 174-180
13. Kazlauskas R.J., Weissfloch A.N.E., Rappaport A.T., and Cuccia L.A. J. Org. Chem. 56 (1991) 2656-2665
14. Hart H., Sambharamadom K.R., and Willer R. J. Org. Chem. 44 (1979) 1-7
15. Russi S., Pardo H., Heinzen H., Días E., Moyna P., Mariezcurrena R., Suescun L., and Mombrú A. Acta Crystallogr., Sect. C (2000) 672-673
16. Desjardins R.E., Canfield C.J., Haynes J.D., and Chulay J.D. Antimicrob. Agents Chemother. 16 (1979) 710-718
17. Budkner F.S., Verlinde C.L., La Flamme A.C., and Van Voortis W.C. Antimicrob. Agents Chemother. 40 (1996) 2592-2597
18. Raz B., Item M., Grether-Buhler Y., Kaminski R., and Brun R. Acta Trop. 68 (1997) 139-147